Optical device for in-line and real-time monitoring of microorganisms

Kacira, Murat; Jia, Fei; Ogden, Kimberly L.; Ogden, Gregory E.

Optical device for in-line and real-time monitoring of microorganisms

Patent · Tue Mar 01 04:00:00 EST 2022

OSTI ID:1892660

Kacira, Murat; Jia, Fei; Ogden, Kimberly L.; Ogden, Gregory E.

A multi-wavelength laser diode based optical sensor system capable of monitoring the dynamics and physiological changes of a microorganism culture in real-time. The microorganism culture from a microorganism production chamber is pumped to a flow chamber. Laser diodes emit light at certain wavelengths through the flow chamber, which is sensed by photodiodes. A laser control circuitry is operatively connected to the laser diodes and a signal conditioning circuitry is operatively connected to the photodiodes. A microprocessor reads and records voltage signals corresponding to the wavelengths. A data acquisition system converts said voltage signals into measurements of biological parameters, which are displayed on a graphical user interface and allow a user to monitor the measurements in real time.

View Patent

Research Organization:: Univ. of Arizona, Tucson, AZ (United States)

Sponsoring Organization:: USDOE

DOE Contract Number:: EE0006269

Assignee:: Arizona Board of Regents on Behalf of the University of Arizona (Tucson, AZ)

Patent Number(s):: 11,261,474

Application Number:: 15/739,467

OSTI ID:: 1892660

Country of Publication:: United States

Language:: English

References (21)

Simultaneous estimation of chlorophylla and lipid contents in microalgae by three-color analysis Su, Chia-Hung; Fu, Chun-Chong; Chang, Yet-Chung Biotechnology and Bioengineering, Vol. 99, Issue 4 https://doi.org/10.1002/bit.21623	journal	January 2008
A photobioreactor system for precision cultivation of photoautotrophic microorganisms and for high-content analysis of suspension dynamics Nedbal, Ladislav; Trtílek, Martin; Červený, Jan Biotechnology and Bioengineering, Vol. 100, Issue 5 https://doi.org/10.1002/bit.21833	journal	January 2008
Heterotrophic production of long chain omega-3 fatty acids utilizing algae and algae-like microorganisms Barclay, W. R.; Meager, K. M.; Abril, J. R. Journal of Applied Phycology, Vol. 6, Issue 2 https://doi.org/10.1007/BF02186066	journal	April 1994
Stress-Induced Changes in Optical Properties, Pigment and Fatty Acid Content of Nannochloropsis sp.: Implications for Non-destructive Assay of Total Fatty Acids Solovchenko, Alexei; Khozin-Goldberg, Inna; Recht, Lee Marine Biotechnology, Vol. 13, Issue 3 https://doi.org/10.1007/s10126-010-9323-x	journal	September 2010
A photobioreactor system for computer controlled cultivation of microalgae Marxen, Kai; Vanselow, Klaus Heinrich; Lippemeier, Sebastian Journal of Applied Phycology, Vol. 17, Issue 6 https://doi.org/10.1007/s10811-005-9004-8	journal	December 2005
Optimization of a flat plate glass reactor for mass production of Nannochloropsis sp. outdoors Richmond, Amos; Cheng-Wu, Zhang Journal of Biotechnology, Vol. 85, Issue 3 https://doi.org/10.1016/S0168-1656(00)00353-9	journal	February 2001
Night biomass loss and changes in biochemical composition of cells during light/dark cyclic culture of Chlorella pyrenoidosa Ogbonna, James C.; Tanaka, Hideo Journal of Fermentation and Bioengineering, Vol. 82, Issue 6 https://doi.org/10.1016/S0922-338X(97)81252-4	journal	January 1996
A simple, reproducible and sensitive spectrophotometric method to estimate microalgal lipids Chen, Yimin; Vaidyanathan, Seetharaman Analytica Chimica Acta, Vol. 724 https://doi.org/10.1016/j.aca.2012.02.049	journal	April 2012
An experimental helical-tubular photobioreactor for continuous production of Nannochloropsis sp. Briassoulis, D.; Panagakis, P.; Chionidis, M. Bioresource Technology, Vol. 101, Issue 17 https://doi.org/10.1016/j.biortech.2010.03.103	journal	September 2010
Biodiesel from microalgae Chisti, Yusuf Biotechnology Advances, Vol. 25, Issue 3, p. 294-306 https://doi.org/10.1016/j.biotechadv.2007.02.001	journal	May 2007
Real-time monitoring and automatic density control of large-scale microalgal cultures using near infrared (NIR) optical density sensors Sandnes, J. M.; Ringstad, T.; Wenner, D. Journal of Biotechnology, Vol. 122, Issue 2 https://doi.org/10.1016/j.jbiotec.2005.08.034	journal	March 2006
Comparative analysis of the outdoor culture of Haematococcus pluvialis in tubular and bubble column photobioreactors López, M. C. García-Malea; Sánchez, E. Del Río; López, J. L. Casas Journal of Biotechnology, Vol. 123, Issue 3 https://doi.org/10.1016/j.jbiotec.2005.11.010	journal	May 2006
Microalgae for biodiesel production and other applications: A review Mata, Teresa M.; Martins, António A.; Caetano, Nidia. S. Renewable and Sustainable Energy Reviews, Vol. 14, Issue 1, p. 217-232 https://doi.org/10.1016/j.rser.2009.07.020	journal	January 2010
Bioprocess engineering of microalgae to produce a variety of consumer products Harun, Razif; Singh, Manjinder; Forde, Gareth M. Renewable and Sustainable Energy Reviews, Vol. 14, Issue 3, p. 1037-1047 https://doi.org/10.1016/j.rser.2009.11.004	journal	April 2010
Heterotrophic cultures of microalgae: Metabolism and potential products Perez-Garcia, Octavio; Escalante, Froylan M. E.; de-Bashan, Luz E. Water Research, Vol. 45, Issue 1 https://doi.org/10.1016/j.watres.2010.08.037	journal	January 2011
On-Line Determination of Biomass in a Microalga Bioreactor Using a Novel Computerized Flow Injection Analysis System Meireles, L. A.; Azevedo, J. L.; Cunha, J. P. Biotechnology Progress, Vol. 18, Issue 6 https://doi.org/10.1021/bp020283u	journal	December 2002
Determination of biomass dry weight of marine microalgae Zhu, C. J.; Lee, Y. K. Journal of Applied Phycology, Vol. 9, Issue 2, p. 189-194 https://doi.org/10.1023/A:1007914806640	journal	April 1997
An optical method for the rapid measurement of micromolar concentrations of nitrate in marine phytoplankton cultures Collos, Y.; Mornet, F.; Sciandra, A. Journal of Applied Phycology, Vol. 11, Issue 2, p. 179-184 https://doi.org/10.1023/A:1008046023487	journal	April 1999
Extraction of pigments and fatty acids from the green alga Scenedesmus obliquus (Chlorophyceae) Wiltshire, Karen H.; Boersma, Maarten; Möller, Anita Aquatic Ecology, Vol. 34, Issue 2, p. 119-126 https://doi.org/10.1023/A:1009911418606	journal	June 2000
Genetic Engineering of Algae for Enhanced Biofuel Production Radakovits, R.; Jinkerson, R. E.; Darzins, A. Eukaryotic Cell, Vol. 9, Issue 4, p. 486-501 https://doi.org/10.1128/EC.00364-09	journal	February 2010
Process Design and Economics for the Conversion of Algal Biomass to Hydrocarbons: Whole Algae Hydrothermal Liquefaction and Upgrading Jones, Susanne B.; Zhu, Yunhua; Anderson, Daniel B. https://doi.org/10.2172/1126336 PNNL--23227	report	March 2014

Similar Records

Multi-Wavelength Based Optical Density Sensor for Autonomous Monitoring of Microalgae

Journal Article · Tue Sep 01 20:00:00 EDT 2015 · Sensors · OSTI ID:1592715

Power control system for a semiconductor laser

Patent · Tue Aug 04 00:00:00 EDT 1987 · OSTI ID:6032249

Temperature stabilization of injection lasers

Patent · Tue Jul 28 00:00:00 EDT 1987 · OSTI ID:6084125

Related Subjects

47 OTHER INSTRUMENTATION

Optical device for in-line and real-time monitoring of microorganisms

Citation Formats

References (21)

Similar Records

Related Subjects