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Silicon electronics on silk as a path to bioresorbable, implantable devices

Journal Article · · Applied Physics Letters
DOI:https://doi.org/10.1063/1.3238552· OSTI ID:1876186
 [1];  [2];  [3];  [3];  [3];  [3];  [4];  [2]
  1. Univ. of Illinois at Urbana-Champaign, IL (United States); University of Illinois
  2. Univ. of Illinois at Urbana-Champaign, IL (United States)
  3. Tufts Univ., Medford, MA (United States)
  4. Defense Advanced Research Projects Agency, Arlington, VA (United States)

Many existing and envisioned classes of implantable biomedical devices require high performance electronics/sensors. An approach that avoids some of the longer term challenges in biocompatibility involves a construction in which some parts or all of the system resorbs in the body over time. Furthermore, this paper describes strategies for integrating single crystalline silicon electronics, where the silicon is in the form of nanomembranes, onto water soluble and biocompatible silk substrates. Electrical, bending, water dissolution, and animal toxicity studies suggest that this approach might provide many opportunities for future biomedical devices and clinical applications.

Research Organization:
Univ. of Illinois at Urbana-Champaign, IL (United States)
Sponsoring Organization:
USDOE Office of Science (SC), Basic Energy Sciences (BES). Materials Sciences & Engineering Division; U.S. Army Research Laboratory; U.S. Army Research Office
Grant/Contract Number:
FG02-07ER46471; FG02-07ER46453
OSTI ID:
1876186
Journal Information:
Applied Physics Letters, Journal Name: Applied Physics Letters Journal Issue: 13 Vol. 95; ISSN 0003-6951
Publisher:
American Institute of Physics (AIP)Copyright Statement
Country of Publication:
United States
Language:
English

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Dissolution Behaviors and Applications of Silicon Oxides and Nitrides in Transient Electronics journal April 2014
Programing Performance of Wool Keratin and Silk Fibroin Composite Materials by Mesoscopic Molecular Network Reconstruction journal August 2016
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Bioresorbable Electronic Implants: History, Materials, Fabrication, Devices, and Clinical Applications journal April 2019
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Metamaterial Silk Composites at Terahertz Frequencies journal July 2010
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Flexible Organic Thin-Film Transistors with Silk Fibroin as the Gate Dielectric journal March 2011
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Group IV Nanoparticles: Synthesis, Properties, and Biological Applications journal August 2010
Stretchable Field-Effect-Transistor Array of Suspended SnO2 Nanowires journal April 2011
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Controllably degradable transient electronic antennas based on water-soluble PVA/TiO2 films journal October 2017
Flammable carbon nanotube transistors on a nitrocellulose paper substrate for transient electronics journal September 2016
Silk: A Promising Biomaterial Opening New Vistas Towards Affordable Healthcare Solutions journal August 2019
Tissue–electronics interfaces: from implantable devices to engineered tissues journal November 2017
Graphene-based wireless bacteria detection on tooth enamel journal January 2012
Dissolvable films of silk fibroin for ultrathin conformal bio-integrated electronics journal April 2010
Thermally Triggered Mechanically Destructive Electronics Based On Electrospun Poly(ε-caprolactone) Nanofibrous Polymer Films journal April 2017
A Silk Fibroin Bio-Transient Solution Processable Memristor journal November 2017
Transient Light Emitting Devices Based on Soluble Polymer Composites journal April 2018
Liquid crystal models of biological materials and processes journal January 2010
Self-deployable current sources fabricated from edible materials journal January 2013
One-step synthesis of biocompatible magnetite/silk fibroin core–shell nanoparticles journal January 2014
Effect of different fabrication methods on the chemo-physical properties of silk fibroin films and on their interaction with neural cells journal January 2016
Biodegradable electronics: cornerstone for sustainable electronics and transient applications journal January 2016
New insights and perspectives into biological materials for flexible electronics journal January 2017
Advances and challenges of green materials for electronics and energy storage applications: from design to end-of-life recovery journal January 2018
Dissolvable tattoo sensors: from science fiction to a viable technology journal November 2016
Transparent and flexible resistive switching memory devices with a very high ON/OFF ratio using gold nanoparticles embedded in a silk protein matrix journal August 2013
Moisture-triggered physically transient electronics journal September 2017
New Opportunities for an Ancient Material journal July 2010
Conducting Polymer-Based Composite Materials for Therapeutic Implantations: From Advanced Drug Delivery System to Minimally Invasive Electronics journal February 2020
Biodegradable and biocompatible polymers for electronic applications: A review journal November 2018
Spider silk inspired materials and sustainability: perspective journal July 2015
Nanowire transistor arrays for mapping neural circuits in acute brain slices. text January 2010
Regenerating leather waste for flexible pressure sensing applications journal August 2019
Synthesis and characterization of biocompatible nanodiamond-silk hybrid material journal January 2014
Inorganic dissolvable electronics: materials and devices for biomedicine and environment journal August 2016
Materials for stretchable electronics journal March 2012
A bilayered PVA/PLGA-bioresorbable shuttle to improve the implantation of flexible neural probes. text January 2018
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