Implantable biomedical devices on bioresorbable substrates
Provided herein are implantable biomedical devices, methods of administering implantable biomedical devices, methods of making implantable biomedical devices, and methods of using implantable biomedical devices to actuate a target tissue or sense a parameter associated with the target tissue in a biological environment. Each implantable biomedical device comprises a bioresorbable substrate, an electronic device having a plurality of inorganic semiconductor components supported by the bioresorbable substrate, and a barrier layer encapsulating at least a portion of the inorganic semiconductor components. Upon contact with a biological environment the bioresorbable substrate is at least partially resorbed, thereby establishing conformal contact between the implantable biomedical device and the target tissue in the biological environment.
- Research Organization:
- University of Illinois, Urbana, IL, USA
- Sponsoring Organization:
- USDOE
- DOE Contract Number:
- FG02-07ER46471; FG02-91ER45439
- Assignee:
- The Board of Trustees of the University of Illinois (Urbana, IL); Northwestern University (Evanston, IL); Trustees of Tufts College (Medford, MA); The Trustees of the University of Pennsylvania (Philadelphia, PA)
- Patent Number(s):
- 8,666,471
- Application Number:
- 12/892,001
- OSTI ID:
- 1126884
- Country of Publication:
- United States
- Language:
- English
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