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Title: Implantable biomedical devices on bioresorbable substrates

Abstract

Provided herein are implantable biomedical devices, methods of administering implantable biomedical devices, methods of making implantable biomedical devices, and methods of using implantable biomedical devices to actuate a target tissue or sense a parameter associated with the target tissue in a biological environment. Each implantable biomedical device comprises a bioresorbable substrate, an electronic device having a plurality of inorganic semiconductor components supported by the bioresorbable substrate, and a barrier layer encapsulating at least a portion of the inorganic semiconductor components. Upon contact with a biological environment the bioresorbable substrate is at least partially resorbed, thereby establishing conformal contact between the implantable biomedical device and the target tissue in the biological environment.

Inventors:
; ; ; ; ; ; ;
Publication Date:
Research Org.:
University of Illinois, Urbana, IL, USA
Sponsoring Org.:
USDOE
OSTI Identifier:
1126884
Patent Number(s):
8,666,471
Application Number:
12/892,001
Assignee:
The Board of Trustees of the University of Illinois (Urbana, IL); Northwestern University (Evanston, IL); Trustees of Tufts College (Medford, MA); The Trustees of the University of Pennsylvania (Philadelphia, PA)
DOE Contract Number:  
FG02-07ER46471; FG02-91ER45439
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
60 APPLIED LIFE SCIENCES

Citation Formats

Rogers, John A, Kim, Dae-Hyeong, Omenetto, Fiorenzo, Kaplan, David L, Litt, Brian, Viventi, Jonathan, Huang, Yonggang, and Amsden, Jason. Implantable biomedical devices on bioresorbable substrates. United States: N. p., 2014. Web.
Rogers, John A, Kim, Dae-Hyeong, Omenetto, Fiorenzo, Kaplan, David L, Litt, Brian, Viventi, Jonathan, Huang, Yonggang, & Amsden, Jason. Implantable biomedical devices on bioresorbable substrates. United States.
Rogers, John A, Kim, Dae-Hyeong, Omenetto, Fiorenzo, Kaplan, David L, Litt, Brian, Viventi, Jonathan, Huang, Yonggang, and Amsden, Jason. Tue . "Implantable biomedical devices on bioresorbable substrates". United States. https://www.osti.gov/servlets/purl/1126884.
@article{osti_1126884,
title = {Implantable biomedical devices on bioresorbable substrates},
author = {Rogers, John A and Kim, Dae-Hyeong and Omenetto, Fiorenzo and Kaplan, David L and Litt, Brian and Viventi, Jonathan and Huang, Yonggang and Amsden, Jason},
abstractNote = {Provided herein are implantable biomedical devices, methods of administering implantable biomedical devices, methods of making implantable biomedical devices, and methods of using implantable biomedical devices to actuate a target tissue or sense a parameter associated with the target tissue in a biological environment. Each implantable biomedical device comprises a bioresorbable substrate, an electronic device having a plurality of inorganic semiconductor components supported by the bioresorbable substrate, and a barrier layer encapsulating at least a portion of the inorganic semiconductor components. Upon contact with a biological environment the bioresorbable substrate is at least partially resorbed, thereby establishing conformal contact between the implantable biomedical device and the target tissue in the biological environment.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2014},
month = {3}
}

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Flexible displays
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