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Omics-Lethal Human Viruses, Ebola Experiment EHUH002

Dataset ·
 [1];  [2];  [3]
  1. Pacific Northwest National Laboratory (PNNL), Richland, WA (United States); Pacific Northwest National Laboratory, Biological Sciences Division
  2. Univ. of Wisconsin, Madison, WI (United States). School of Veterinary Medicine. Pathology Department
  3. Pacific Northwest National Laboratory (PNNL), Richland, WA (United States)
+ Show Author Affiliations

The purpose of this experiment was to evaluate the human host response to Zaire Ebola wild-type virus and mutant virus infection. Samples were obtained from human hepatoma carcinoma cells (HUH-7) infected with Zaire Ebola ΔVP30-WT background for proteome, metabolome, and lipidome expression analysis. Secondary host-associated viral dataset downloads contain one or more statistically processed (normalization data transformation) quantitative dataset collections resulting in qualitative expression analyses of primary host-pathogen experimental study designs. Leveraging unique high-resolution Omics capabilities for proteomics, metabolomics, and lipidomics dataset downloads each have a direct relationship to a primary sample submission corresponding to a specific Ebola virus infection.

Research Organization:
Pacific Northwest National Laboratory (PNNL), Richland, WA (United States)
Sponsoring Organization:
USDOE Office of Science (SC); National Institute of Allergy and Infectious Diseases (NIAID)
Contributing Organization:
Modeling Host Responses to Understand Severe Human Virus Infections Program Project
DOE Contract Number:
AC05-76RL01830
OSTI ID:
1661906
Report Number(s):
EHUH002; MassIVE: MSV000081041 (proteome); MassIVE: MSV000081042 (metabolome); MassIVE: MSV000081892 (lipidome)
Availability:
rc-support@pnnl.gov
Country of Publication:
United States
Language:
English

Cited By (1)

PNNL DataHub Project Omics-LHV Profiling of Host Response to Ebola Infection Post-Processed Data Package DOIs dataset January 2021

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Related Subjects

59 BASIC BIOLOGICAL SCIENCES
Data Download [schema:DataDownload]
Ebola virus [NCBITAXON:186536]
Human virus [NCIT:C14317]
Immune Response [GO:0006955]
Mass spectrometry data [edam.data:2536]
MassIVE dataset identifier [MS:1002487]
Multi-omics [edam.topic:4021]
Omics [edam.topic:3391]
Time Sampled Measurement Datasets [IAO:0000584]
Virology [edam.topic:0781]
data transformation [SIO:000594]
differential expression analysis [SWO:7000018]