Strong Electroosmotic Coupling Dominates Ion Conductance of 1.5 nm Diameter Carbon Nanotube Porins

Yao, Yun-Chiao; Taqieddin, Amir; Alibakhshi, Mohammad A.; Wanunu, Meni; Aluru, Narayana R.; Noy, Aleksandr

doi:10.1021/acsnano.9b05118

Strong Electroosmotic Coupling Dominates Ion Conductance of 1.5 nm Diameter Carbon Nanotube Porins

Journal Article · Mon Nov 04 00:00:00 EST 2019 · ACS Nano

DOI:https://doi.org/10.1021/acsnano.9b05118· OSTI ID:1657684

Yao, Yun-Chiao ^[1]; Taqieddin, Amir ^[2]; Alibakhshi, Mohammad A. ^[3]; ^[3]; Aluru, Narayana R. ^[2]; ^[1]

Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Univ. of California, Merced, CA (United States)
Univ. of Illinois at Urbana-Champaign, IL (United States)
Northeastern Univ., Boston, MA (United States)

Extreme confinement in nanometer sized channels can alter fluid and ion transport in significant ways, leading to significant water flow enhancement and unusual ion correlation effects. These effects are especially pronounced in carbon nanotube porins (CNTPs) that combine strong confinement in the inner lumen of carbon nanotubes with the high slip flow enhancement due to smooth hydrophobic pore walls. For this paper, we have studied ion transport and ion selectivity in 1.5 nm diameter CNTPs embedded in lipid membranes using single nanopore measurement setup. Our data show that CNTPs are weakly cation-selective at pH 7.5 and become non-selective at pH 3.0. Ion conductance of CNTPs exhibits an unusual 2/3 power law scaling with the ion concentration at both neutral and acidic pH values. Coupled Navier-Stokes and Poisson-Nernst-Planck (NS-PNP) simulations and atomistic Molecular Dynamics (MD) simulations reveal that this scaling originates from strong coupling between water and ion transport in these channels. These effects could result in development of a next generation of biomimetic membranes and carbon nanotube-based electroosmotic pumps.

View Accepted Manuscript (DOE)

Research Organization:: Energy Frontier Research Centers (EFRC) (United States). The Center for Enhanced Nanofluidic Transport (CENT); Lawrence Livermore National Laboratory (LLNL), Livermore, CA (United States)

Sponsoring Organization:: National Science Foundation (NSF); USDOE National Nuclear Security Administration (NNSA); USDOE Office of Science (SC), Basic Energy Sciences (BES). Materials Sciences & Engineering Division

Grant/Contract Number:: AC02-05CH11231; AC52-07NA27344; SC0019112

OSTI ID:: 1657684

Report Number(s):: LLNL-JRNL--780109; 974823

Journal Information:: ACS Nano, Journal Name: ACS Nano Journal Issue: 11 Vol. 13; ISSN 1936-0851

Publisher:: American Chemical Society (ACS)Copyright Statement

Country of Publication:: United States

Language:: English

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Strong Electroosmotic Coupling Dominates Ion Conductance of 1.5 nm Diameter Carbon Nanotube Porins

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