Thirdhand smoke: Genotoxicity and carcinogenic potential

Hang, Bo; Wang, Pin; Zhao, Yue; Chang, Hang; Mao, Jian-Hua; Snijders, Antoine M.

doi:10.1016/j.cdtm.2019.08.002

Thirdhand smoke: Genotoxicity and carcinogenic potential

Journal Article · Thu Sep 26 00:00:00 EDT 2019 · Chronic Diseases and Translational Medicine

DOI:https://doi.org/10.1016/j.cdtm.2019.08.002· OSTI ID:1637309

Hang, Bo ^[1]; Wang, Pin ^[2]; Zhao, Yue ^[3]; Chang, Hang ^[1]; Mao, Jian-Hua ^[1]; Snijders, Antoine M. ^[1]

Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States). Biological Systems and Engineering Division
Nanjing Univ. Medical School, Jiangsu (China)
Peking Univ. Third Hospital, Beijing (China)

Thirdhand smoke (THS), the residual tobacco smoke remaining in the environment after tobacco has been smoked, represents a hidden and underestimated public health hazard. Evidence supports its widespread presence in indoor environments. Exposure to secondhand smoke (SHS), a precursor of THS, has been well documented as a risk factor for human cancers, especially lung cancer. However, the concept of THS as a distinct entity that poses health risks for small children has developed only recently and the associations of THS with cancer risk and other chronic diseases are poorly understood due to limited numbers of studies to date. In this perspective, we mainly summarize all published studies on the genotoxicity and carcinogenic potential of THS exposure. These studies begin to fill the knowledge gap in our understanding of cancer risk of THS. Accumulating data from existing and future studies will help reduce the tobacco-related cancer incidence through changes in lifestyle and tobacco control policies.

View Accepted Manuscript (DOE)

Research Organization:: Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States)

Sponsoring Organization:: USDOE Office of Science (SC); University of California Tobacco-Related Disease Research Program

Grant/Contract Number:: AC02-05CH11231

OSTI ID:: 1637309

Journal Information:: Chronic Diseases and Translational Medicine, Journal Name: Chronic Diseases and Translational Medicine Journal Issue: 1 Vol. 6; ISSN 2095-882X

Publisher:: KeAiCopyright Statement

Country of Publication:: United States

Language:: English

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60 APPLIED LIFE SCIENCES
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