Skip to main content
OSTI.GOVU.S. Department of Energy Office of Scientific and Technical Information
U.S. Department of Energy
Office of Scientific and Technical Information
 

Draft Genome Sequence of a Mucoid Isolate of Pseudomonas aeruginosa Strain C7447m from a Patient with Cystic Fibrosis

Journal Article · · Genome Announcements
 [1];  [2];  [3];  [4]
  1. Marshall Univ., Huntington, WV (United States). Joan C. Edwards School of Medicine. Dept. of Biochemistry and Microbiology; DOE/OSTI
  2. Marshall Univ., Huntington, WV (United States). Joan C. Edwards School of Medicine. Dept. of Biochemistry and Microbiology
  3. Los Alamos National Lab. (LANL), Los Alamos, NM (United States). Genome Science Group
  4. Marshall Univ., Huntington, WV (United States). Joan C. Edwards School of Medicine. Dept. of Biochemistry and Microbiology; Marshall Univ., Huntington, WV (United States). Joan C. Edwards School of Medicine. Dept. of Pediatrics; Progenesis Technologies, LLC, Huntington, WV (United States)
+ Show Author Affiliations
Alginate overproduction by Pseudomonas aeruginosa, or mucoidy, plays an important role in the pathogenesis of chronic lung infections in cystic fibrosis (CF) patients. Here we report the draft genome sequence of a clinical isolate of mucoid P. aeruginosa strain C7447m from a CF patient with chronic lung infection.
Research Organization:
Los Alamos National Laboratory (LANL), Los Alamos, NM (United States)
Sponsoring Organization:
USDOE Office of Science (SC), Biological and Environmental Research (BER). Biological Systems Science Division
OSTI ID:
1629341
Journal Information:
Genome Announcements, Journal Name: Genome Announcements Journal Issue: 5 Vol. 1; ISSN 2169-8287
Publisher:
American Society for MicrobiologyCopyright Statement
Country of Publication:
United States
Language:
English

References (6)

Bacterial biosynthesis of alginates journal March 2010
Truncation of type IV pilin induces mucoidy in P seudomonas aeruginosa strain PAO579 journal March 2013
ClpXP proteases positively regulate alginate overexpression and mucoid conversion in Pseudomonas aeruginosa journal July 2008
The Pseudomonas aeruginosa Sensor Kinase KinB Negatively Controls Alginate Production through AlgW-Dependent MucA Proteolysis journal January 2009
Microbial pathogenesis in cystic fibrosis: mucoid Pseudomonas aeruginosa and Burkholderia cepacia journal September 1996
The Exopolysaccharide Alginate Protects Pseudomonas aeruginosa Biofilm Bacteria from IFN-γ-Mediated Macrophage Killing journal November 2005

Cited By (1)

Ribosomally encoded antibacterial proteins and peptides from Pseudomonas journal July 2014

Similar Records

Draft Genome Sequence of a Stable Mucoid Strain of Pseudomonas aeruginosa PAO581 with a mucA25 Mutation
Journal Article · Thu Aug 29 00:00:00 EDT 2013 · Genome Announcements · OSTI ID:1629281
Insights into the respiratory tract microbiota of patients with cystic fibrosis during early Pseudomonas aeruginosa colonization
Journal Article · Sun Aug 09 00:00:00 EDT 2015 · SpringerPlus, 4:Article No. 405 · OSTI ID:1214886
Applying a polysaccharide lyase from Stenotrophomonas maltophilia to disrupt alginate exopolysaccharide produced by Pseudomonas aeruginosa clinical isolates
Journal Article · Thu Dec 12 23:00:00 EST 2024 · Applied and Environmental Microbiology · OSTI ID:2530387

Related Subjects

59 BASIC BIOLOGICAL SCIENCES