Phylogenomic analysis of polyketide synthase-encoding genes in Trichoderma

Baker, Scott E.; Perrone, Giancarlo; Richardson, Nathan M.; Gallo, Antonia; Kubicek, Christian P.

doi:10.1099/mic.0.053462-0

Title: Phylogenomic analysis of polyketide synthase-encoding genes in Trichoderma

Journal Article · Sun Jan 01 00:00:00 EST 2012 · Microbiology

DOI:https://doi.org/10.1099/mic.0.053462-0· OSTI ID:1601800

^[1]; Perrone, Giancarlo ^[2]; Richardson, Nathan M. ^[3]; Gallo, Antonia ^[2]; Kubicek, Christian P. ^[4]

BATTELLE (PACIFIC NW LAB)
CNR-ISPA
WASHINGTON STATE UNIV TC
Technische Universitat Wien

Members of the economically important ascomycete genus Trichoderma are ubiquitously distributed around the world. The mycoparasitic lifestyle and plant defense inducing interactions of Trichoderma spp. make them ideal biocontrol agents. Of the Trichoderma enzymes that produce secondary metabolites, some of which likely play important roles in biocontrol processes, polyketide synthases have garnered less attention that non-ribosomal peptide synthetases such as those that produce peptaibols. We have taken a phylogenomic approach to study the polyketide synthase repertoire encoded in the genomes of Trichoderma reesei, Trichoderma atroviride and Trichoderma virens. Our analysis lays a foundation for future research related to polyketide synthases within the Trichoderma genus and other filamentous fungi.

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Research Organization:: Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

Sponsoring Organization:: USDOE

DOE Contract Number:: AC05-76RL01830

OSTI ID:: 1601800

Report Number(s):: PNNL-SA-84089

Journal Information:: Microbiology, Vol. 158, Issue 1

Country of Publication:: United States

Language:: English

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Title: Phylogenomic analysis of polyketide synthase-encoding genes in Trichoderma

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