Novel traits of Trichoderma predicted through the analysis of its secretome

Druzhinina, Irina S.; Shelest, Ekaterina; Kubicek, Christian P.

doi:10.1111/j.1574-6968.2012.02665.x

Novel traits of Trichoderma predicted through the analysis of its secretome

Journal Article · Fri Nov 30 23:00:00 EST 2012 · FEMS Microbiology Letters

DOI:https://doi.org/10.1111/j.1574-6968.2012.02665.x· OSTI ID:1625904

Druzhinina, Irina S. ^[1]; Shelest, Ekaterina ^[2]; Kubicek, Christian P. ^[3]

Vienna Univ. of Technology (Austria). Inst. of Chemical Engineering. Research Division Biotechnolog and Microbiology; Vienna Univ. of Technology (Austria). Austrian Center of Industrial Biology (ACIB), GmBH; DOE/OSTI
Hans Knoell Inst., Jena (Germany). Leibniz Inst.for Natural Product Research and Infection Biology. Systems Biology/Bioinformatics Research Group
Vienna Univ. of Technology (Austria). Inst. of Chemical Engineering. Research Division Biotechnolog and Microbiology; Vienna Univ. of Technology (Austria). Austrian Center of Industrial Biology (ACIB), GmBH

Mycotrophic species of Trichoderma are among the most common fungi isolated from free soil, dead wood and as parasites on sporocarps of other fungi (mycoparasites). In addition, they undergo various other biotrophic associations ranging from rhizosphere colonization and endophytism up to facultative pathogenesis on such animals as roundworms and humans. Together with occurrence on a variety of less common substrata (marine invertebrates, artificial materials, indoor habitats), these lifestyles illustrate a wealthy opportunistic potential of the fungus. One tropical species, Trichoderma reesei, has become a prominent producer of cellulases and hemicellulases, whereas several other species are applied in agriculture for the biological control of phytopathogenic fungi. The sequencing of the complete genomes of the three species (T. reesei, T. virens, and T. atroviride) has led to a deepened understanding of Trichoderma lifestyle and its molecular physiology. In this review, we present the in silico predicted secretome of Trichoderma, and – in addition to the unique features of carbohydrate active enzymes – demonstrate the importance of such protein families as proteases, oxidative enzymes, and small cysteine-rich proteins, all of that received little attention in Trichoderma genetics so far. We also discuss the link between Trichoderma secretome and biology of the fungus.

View Accepted Manuscript (DOE)

Research Organization:: Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States)

Sponsoring Organization:: USDOE Office of Science (SC), Biological and Environmental Research (BER). Biological Systems Science Division

Grant/Contract Number:: AC02-05CH11231

OSTI ID:: 1625904

Journal Information:: FEMS Microbiology Letters, Journal Name: FEMS Microbiology Letters Journal Issue: 1 Vol. 337; ISSN 0378-1097

Publisher:: Federation of European Microbiological SocietiesCopyright Statement

Country of Publication:: United States

Language:: English

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Novel traits of Trichoderma predicted through the analysis of its secretome

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