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Modular, micro-scale, optical array and biodetection system

Patent ·
OSTI ID:1531573

A modular, micro-scale, optical array and biodetection device for quantifying fluorescence intensities of a plurality of substantially separated, and dimensionally uniform elements of a bioarray that are located at known positions on a plain support includes a light guide that directs bioarray illumination light from a respective light source to opposing sides of the plain support. An optical module collecting light individually from the bioarray elements includes an optical member, a filter, and a sensor, such as a CCD chip. The optical member collects and transfers emitted light from the bioarray elements via the filter to the sensor. The filter transfers light from the elements having a predefined wavelength spectrum and blocks light outside the predefined wavelength spectrum. The sensor receives transferred light from the elements and produces a signal corresponding to respective elements of the bioarray.

Research Organization:
UChicago Argonne, LLC, Chicago, IL (United States)
Sponsoring Organization:
USDOE
DOE Contract Number:
W-31109-ENG-38
Assignee:
UChicago Argonne, LLC (Chicago, IL)
Patent Number(s):
7,463,353
Application Number:
11/444,241
OSTI ID:
1531573
Country of Publication:
United States
Language:
English

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