Tuberculosis-like lesions arising from the use of Freund's complete adjuvant in an owl monkey (Aotus sp)
Journal Article
·
· Journal of Medical Primatology
An apparently normal, non-tuberculin-reacting, splenectomized owl monkey presented tuberculosis-like lesions of the lung at necropsy. Histological and bacteriological examination failed to demonstrate the presence of acid-fast organisms. Retrospective inquiry showed the animal had been inoculated using complete Freund's Adjuvant during a malaria vaccine trial. Lesions observed were compatible with lipid embolism of the adjuvant in the lungs.
- Research Organization:
- Pacific Northwest National Lab., Richland, WA (US)
- Sponsoring Organization:
- US Department of Energy (US)
- DOE Contract Number:
- AC05-76RL01830
- OSTI ID:
- 15011227
- Report Number(s):
- PNWD-SA-5293; TRN: US200505%%36
- Journal Information:
- Journal of Medical Primatology, Vol. 33, Issue 2; Other Information: PBD: 1 Apr 2004
- Country of Publication:
- United States
- Language:
- English
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