Dyscoria associated with herpesvirus infection in owl monkeys (Aotus nancymae)
Journal Article
·
· Journal of the American Association for Laboratory Animal Science, 47(4):68-71
OSTI ID:964620
Abstract Dyscoria was observed in a female owl monkey and her two offspring. A third offspring was found dead with necrohemorrhagic encephalitis. Two males paired with the female died, one of which showed oral ulcers at necropsy. Histologic examination of the oral ulcers revealed syncytia and eosinophilic intranuclear inclusion bodies in epithelial cells. Ocular examination revealed posterior synechia associated with the dyscoria in all three animals. Serum samples from the female and her offspring were positive for Herpesvirus simplex antibodies by enzyme-linked immunosorbent assay. The clinical history, gross and microscopic lesions, and serology results suggests a herpesviral etiology, possibly, H. simplex or H. saimiri-1. This report underscores the risks associated with introducing animals into breeding or research colonies that were previously kept as pets or those from unknown origin that could carry asymptomatic pathogenic Herpesvirus infections. In addition, herpesviral infection should be considered among the differential diagnoses if dyscoria is observed in nonhuman primates.
- Research Organization:
- Pacific Northwest National Laboratory (PNNL), Richland, WA (US)
- Sponsoring Organization:
- USDOE
- DOE Contract Number:
- AC05-76RL01830
- OSTI ID:
- 964620
- Report Number(s):
- PNNL-SA-60216
- Journal Information:
- Journal of the American Association for Laboratory Animal Science, 47(4):68-71, Journal Name: Journal of the American Association for Laboratory Animal Science, 47(4):68-71 Journal Issue: 4 Vol. 47
- Country of Publication:
- United States
- Language:
- English
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