The Texas A&M Radioisotope Production and Radiochemistry Program

Technical Report · Fri Oct 28 04:00:00 EDT 2016

DOI:https://doi.org/10.2172/1333562· OSTI ID:1333562

Akabani, Gamal ^[1]

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1. Texas A & M Univ., College Station, TX (United States). Dept. of Nuclear Engineering. Dept. of Veterinary Integrative Biosciences; Texas A&M University

The main motivation of the project at Texas A&M University was to carry out the production of critically needed radioisotopes used in medicine for diagnostics and therapy, and to establish an academic program in radionuclide production and separation methods. After a lengthy battle with the Texas A&M University Radiation Safety Office, the Texas Department of State Health Services granted us a license for the production of radionuclides in July 2015, allowing us to work in earnest in our project objectives. Experiments began immediately after licensing, and we started the assembly and testing of our target systems. There were four analytical/theoretical projects and two experimental target systems. These were for At-211 production and for Zn-62/Cu-62 production. The theoretical projects were related to the production of Mo-99/Tc-99m using a) a subcritical aqueous target system and b) production of Tc-99m from accelerator-generated Mo-99 utilizing a photon-neutron interaction with enriched Mo-100 targets. The two experimental projects were the development of targetry systems and production of At-211 and Zn-62/Cu-62 generator. The targetry system for At-211 has been tested and production of At-211 is chronic depending of availability of beam time at the cyclotron. The installation and testing of the targetry system for the production of Zn-62/Cu-62 has not been finalized. A description of the systems is described. The academic program in radionuclide production and separation methods was initiated in the fall of 2011 and, due to the lack of a radiochemistry laboratory, it was suspended. We expect to re-start the academic program at the Texas A&M Institute for Preclinical Studies under the Molecular Imaging Program.

• Research Organization: Texas A & M Univ., College Station, TX (United States)
• Sponsoring Organization: USDOE Office of Science (SC)
• DOE Contract Number: SC0007371
• OSTI ID: 1333562
• Report Number(s): DE--SC0007371
• Country of Publication: United States
• Language: English

Related Subjects

38 RADIATION CHEMISTRY, RADIOCHEMISTRY, AND NUCLEAR CHEMISTRY
43 PARTICLE ACCELERATORS
ASTATINE 211
At-211
BIOMEDICAL RADIOGRAPHY
COPPER 62
ISOTOPE PRODUCTION
MOLYBDENUM 100 TARGET
MOLYBDENUM 99
Mo-99/Tc-99m
PHOTONEUTRONS
PHOTONUCLEAR REACTIONS
RADIOCHEMISTRY
RADIOPHARMACEUTICALS
TARGETS
TECHNETIUM 99
TESTING
TEXAS
ZINC 62
Zn-62/Cu-62