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Title: Isolation of 163Ho from dysprosium target material by HPLC for neutrino mass measurements

Abstract

The rare earth isotope 163Ho is of interest for neutrino mass measurements. This report describes the isolation of 163Ho from a proton-irradiated dysprosium target and its purification. A Dy metal target was irradiated with 16 MeV protons for 10 h. After target dissolution, 163Ho was separated from the bulk Dy via cation-exchange high performance liquid chromatography using 70 mmol dm –3 α-hydroxyisobutyric acid as the mobile phase. Subsequent purification of the collected Ho fraction was performed to remove the α-hydroxyisobutyrate chelating agent and to concentrate the Ho in a low ionic strength aqueous matrix. The final solution was characterized by MC-ICP-MS to determine the 163Ho/ 165Ho ratio, 163Ho and the residual Dy content. The HPLC purification process resulted in a decontamination factor 1.4E5 for Dy. As a result, the isolated Ho fraction contained 24.8 ±1.3 ng of 163Ho corresponding to holmium recovery of 72 ± 3%.

Authors:
 [1];  [1];  [1];  [1];  [2];  [2];  [1];  [1];  [1];  [1]
  1. Los Alamos National Lab. (LANL), Los Alamos, NM (United States)
  2. Univ. of Wisconsin, Madison, WI (United States)
Publication Date:
Research Org.:
Los Alamos National Lab. (LANL), Los Alamos, NM (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1239303
Report Number(s):
LA-UR-14-28326
Journal ID: ISSN 0033-8230
Grant/Contract Number:  
AC52-06NA25396
Resource Type:
Journal Article: Accepted Manuscript
Journal Name:
Radiochimica Acta
Additional Journal Information:
Journal Volume: 103; Journal Issue: 8; Journal ID: ISSN 0033-8230
Publisher:
de Gruyter
Country of Publication:
United States
Language:
English
Subject:
37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY; 38 RADIATION CHEMISTRY, RADIOCHEMISTRY, AND NUCLEAR CHEMISTRY; HPLC; 163Ho; lanthanide separation; neutrino mass; preparative HPLC

Citation Formats

Mocko, Veronika, Taylor, Wayne  A., Nortier, Francois M., Engle, Jonathan  W., Barnhart, Todd  E., Nickles, Robert  J., Pollington, Anthony  D., Kunde, Gerd  J., Rabin, Michael  W., and Birnbaum, Eva  R.. Isolation of 163Ho from dysprosium target material by HPLC for neutrino mass measurements. United States: N. p., 2015. Web. doi:10.1515/ract-2014-2362.
Mocko, Veronika, Taylor, Wayne  A., Nortier, Francois M., Engle, Jonathan  W., Barnhart, Todd  E., Nickles, Robert  J., Pollington, Anthony  D., Kunde, Gerd  J., Rabin, Michael  W., & Birnbaum, Eva  R.. Isolation of 163Ho from dysprosium target material by HPLC for neutrino mass measurements. United States. doi:10.1515/ract-2014-2362.
Mocko, Veronika, Taylor, Wayne  A., Nortier, Francois M., Engle, Jonathan  W., Barnhart, Todd  E., Nickles, Robert  J., Pollington, Anthony  D., Kunde, Gerd  J., Rabin, Michael  W., and Birnbaum, Eva  R.. Wed . "Isolation of 163Ho from dysprosium target material by HPLC for neutrino mass measurements". United States. doi:10.1515/ract-2014-2362. https://www.osti.gov/servlets/purl/1239303.
@article{osti_1239303,
title = {Isolation of 163Ho from dysprosium target material by HPLC for neutrino mass measurements},
author = {Mocko, Veronika and Taylor, Wayne  A. and Nortier, Francois M. and Engle, Jonathan  W. and Barnhart, Todd  E. and Nickles, Robert  J. and Pollington, Anthony  D. and Kunde, Gerd  J. and Rabin, Michael  W. and Birnbaum, Eva  R.},
abstractNote = {The rare earth isotope 163Ho is of interest for neutrino mass measurements. This report describes the isolation of 163Ho from a proton-irradiated dysprosium target and its purification. A Dy metal target was irradiated with 16 MeV protons for 10 h. After target dissolution, 163Ho was separated from the bulk Dy via cation-exchange high performance liquid chromatography using 70 mmol dm–3 α-hydroxyisobutyric acid as the mobile phase. Subsequent purification of the collected Ho fraction was performed to remove the α-hydroxyisobutyrate chelating agent and to concentrate the Ho in a low ionic strength aqueous matrix. The final solution was characterized by MC-ICP-MS to determine the 163Ho/165Ho ratio, 163Ho and the residual Dy content. The HPLC purification process resulted in a decontamination factor 1.4E5 for Dy. As a result, the isolated Ho fraction contained 24.8 ±1.3 ng of 163Ho corresponding to holmium recovery of 72 ± 3%.},
doi = {10.1515/ract-2014-2362},
journal = {Radiochimica Acta},
number = 8,
volume = 103,
place = {United States},
year = {Wed Apr 29 00:00:00 EDT 2015},
month = {Wed Apr 29 00:00:00 EDT 2015}
}

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