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Monolithic microfluidic concentrators and mixers

Patent ·
OSTI ID:1175338
Microfluidic devices comprising porous monolithic polymer for concentration, extraction or mixing of fluids. A method for in situ preparation of monolithic polymers by in situ initiated polymerization of polymer precursors within microchannels of a microfluidic device and their use for solid phase extraction (SPE), preconcentration, concentration and mixing.
Research Organization:
The Regents of the University of California, Oakland, CA (United States); Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States)
Sponsoring Organization:
USDOE
DOE Contract Number:
AC03-76SF00098
Assignee:
The Regents of the University of California (Oakland, CA)
Patent Number(s):
6,887,384
Application Number:
10/251,604
OSTI ID:
1175338
Country of Publication:
United States
Language:
English

References (21)

Electrochemically Actuated Mercury Pump for Fluid Flow and Delivery journal January 2001
Microfluidic Devices for Electrokinetically Driven Parallel and Serial Mixing journal October 1999
Fabrication of Phospholipid Bilayer-Coated Microchannels for On-Chip Immunoassays journal January 2001
Partial electroosmotic pumping in complex capillary systems journal February 2001
Chiral Monolithic Columns for Enantioselective Capillary Electrochromatography Prepared by Copolymerization of a Monomer with Quinidine Functionality. 1. Optimization of Polymerization Conditions, Porous Properties, and Chemistry of the Stationary Phase journal October 2000
On-Line Concentration of Neutral Analytes for Micellar Electrokinetic Chromatography. 5. Field-Enhanced Sample Injection with Reverse Migrating Micelles journal May 1998
Optimization of confocal epifluorescence microscopy for microchip-based miniaturized total analysis systems journal January 1998
Microstructure for efficient continuous flow mixing journal January 1999
Grafted Macroporous Polymer Monolithic Disks:  A New Format of Scavengers for Solution-Phase Combinatorial Chemistry journal March 2001
Microfabricated Porous Membrane Structure for Sample Concentration and Electrophoretic Analysis journal May 1999
Passive mixing in a three-dimensional serpentine microchannel journal June 2000
Trapping of Bead-Based Reagents within Microfluidic Systems:  On-Chip Solid-Phase Extraction and Electrochromatography journal February 2000
Dispersion Reduction in Pressure-Driven Flow Through Microetched Channels journal February 2001
Electroosmotically Induced Hydraulic Pumping on Microchips:  Differential Ion Transport journal May 2000
Monolithic Porous Polymer for On-Chip Solid-Phase Extraction and Preconcentration Prepared by Photoinitiated in Situ Polymerization within a Microfluidic Device journal November 2001
Porous Polymer Monoliths:  Preparation of Sorbent Materials with High-Surface Areas and Controlled Surface Chemistry for High-Throughput, Online, Solid-Phase Extraction of Polar Organic Compounds journal December 1998
Towards stationary phases for chromatography on a microchip: Molded porous polymer monoliths prepared in capillaries by photoinitiated in situ polymerization as separation media for electrochromatography journal January 2000
Synthesis and Evaluation of a Molecularly Imprinted Polymer for Selective On-Line Solid-Phase Extraction of 4-Nitrophenol from Environmental Water journal September 2000
Monitoring Process-Scale Reactions Using API Mass Spectrometry journal November 1999
Microfabricated Silicon Mixers for Submillisecond Quench-Flow Analysis journal January 1998
A Picoliter-Volume Mixer for Microfluidic Analytical Systems journal May 2001

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