Nanolipoprotein particles and related compositions, methods and systems

Hoeprich, Paul D; Fischer, Nicholas O; Mason, Peter W; Blanchette, Craig D

Nanolipoprotein particles and related compositions, methods and systems

Patent · 10 November 2014

OSTI ID:1163677

Hoeprich, Paul D; Fischer, Nicholas O; Mason, Peter W; Blanchette, Craig D

Functionalized nanolipoprotein particle presenting an anchor substrate compound for binding with a corresponding anchor compound presented on a target molecule, and related compositions methods and systems.

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Research Organization:: Lawrence Livermore National Laboratory (LLNL), Livermore, CA (United States)

Sponsoring Organization:: USDOE

DOE Contract Number:: AC52-07NA27344

Assignee:: Lawrence Livermore National Security, LLC (Livermore, CA)

Patent Number(s):: 8,883,729

Application Number:: 12/469,533

OSTI ID:: 1163677

Country of Publication:: United States

Language:: English

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G-Protein-Coupled Receptor Microarrays for Multiplexed Compound Screening Hong, Yulong; Webb, Brian L.; Pai, Sadashiva Journal of Biomolecular Screening, Vol. 11, Issue 4 https://doi.org/10.1177/1087057106287139	journal	June 2006
In-depth analysis of the membrane and cytosolic proteome of red blood cells Pasini, Erica M.; Kirkegaard, Morten; Mortensen, Peter Blood, Vol. 108, Issue 3 https://doi.org/10.1182/blood-2005-11-007799	journal	August 2006
Quantifying size distributions of nanolipoprotein particles with single-particle analysis and molecular dynamic simulations Blanchette, Craig D.; Law, Richard; Benner, W. Henry Journal of Lipid Research, Vol. 49, Issue 7 https://doi.org/10.1194/jlr.M700586-JLR200	journal	April 2008
High-Yield Hydrogen Production from Starch and Water by a Synthetic Enzymatic Pathway Zhang, Y.-H. Percival; Evans, Barbara R.; Mielenz, Jonathan R. PLoS ONE, Vol. 2, Issue 5, Article No. e456 https://doi.org/10.1371/journal.pone.0000456	journal	May 2007
Molecular Dynamics Simulations of Discoidal Bilayers Assembled from Truncated Human Lipoproteins Shih, Amy Y.; Denisov, Ilia G.; Phillips, James C. Biophysical Journal, Vol. 88, Issue 1 https://doi.org/10.1529/biophysj.104.046896	journal	January 2005
Atomic Force Microscope Spectroscopy Reveals a Hemifusion Intermediate during Soluble N-Ethylmaleimide-Sensitive Factor-Attachment Protein Receptors-Mediated Membrane Fusion Abdulreda, Midhat H.; Bhalla, Akhil; Chapman, Edwin R. Biophysical Journal, Vol. 94, Issue 2 https://doi.org/10.1529/biophysj.107.114298	journal	January 2008
Functional reconstitution of β ₂ -adrenergic receptors utilizing self-assembling Nanodisc technology Leitz, Andrew J.; Bayburt, Timothy H.; Barnakov, Alexander N. BioTechniques, Vol. 40, Issue 5 https://doi.org/10.2144/000112169	journal	May 2006
Corticotropin Releasing Factor (CRF) Receptor Signaling in the Central Nervous System: New Molecular Targets Hauger, Richard; Risbrough, Victoria; Brauns, Olaf CNS & Neurological Disorders - Drug Targets, Vol. 5, Issue 4 https://doi.org/10.2174/187152706777950684	journal	August 2006
Characterization and Purification of Polydisperse Reconstituted Lipoproteins and Nanolipoprotein Particles Blanchette, Craig; Segelke, Brent; Fischer, Nicholas International Journal of Molecular Sciences, Vol. 10, Issue 7 https://doi.org/10.3390/ijms10072958	journal	July 2009
A Potent Adjuvant Monophosphoryl Lipid A Triggers Various Immune Responses, but Not Secretion of IL-1β or Activation of Caspase-1 Okemoto, Kazuo; Kawasaki, Kiyoshi; Hanada, Kentaro The Journal of Immunology, Vol. 176, Issue 2 https://doi.org/10.4049/jimmunol.176.2.1203	journal	January 2006

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