Plume collimation for laser ablation electrospray ionization mass spectrometry

Vertes, Akos; Stolee, Jessica A.

Plume collimation for laser ablation electrospray ionization mass spectrometry

Patent · Tue Sep 09 04:00:00 EDT 2014

OSTI ID:1157080

Vertes, Akos; Stolee, Jessica A.

In various embodiments, a device may generally comprise a capillary having a first end and a second end; a laser to emit energy at a sample in the capillary to ablate the sample and generate an ablation plume in the capillary; an electrospray apparatus to generate an electrospray plume to intercept the ablation plume to produce ions; and a mass spectrometer having an ion transfer inlet to capture the ions. The ablation plume may comprise a collimated ablation plume. The device may comprise a flow cytometer. Methods of making and using the same are also described.

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Research Organization:: The George Washington University, Washington, DC (United States)

Sponsoring Organization:: USDOE

DOE Contract Number:: FG02-01ER15129

Assignee:: The George Washington University (Washington, DC)

Patent Number(s):: 8,829,426

Application Number:: 13/549,988

OSTI ID:: 1157080

Country of Publication:: United States

Language:: English

References (17)

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