High temperature flow-through device for rapid solubilization and analysis

West, Jason A. A.; Hukari, Kyle W.; Patel, Kamlesh D.; Peterson, Kenneth A.; Renzi, Ronald F.

High temperature flow-through device for rapid solubilization and analysis

Patent · Tue Apr 23 04:00:00 EDT 2013

OSTI ID:1083601

West, Jason A. A.; Hukari, Kyle W.; Patel, Kamlesh D.; Peterson, Kenneth A.; Renzi, Ronald F.

Devices and methods for thermally lysing of biological material, for example vegetative bacterial cells and bacterial spores, are provided. Hot solution methods for solubilizing bacterial spores are described. Systems for direct analysis are disclosed including thermal lysers coupled to sample preparation stations. Integrated systems capable of performing sample lysis, labeling and protein fingerprint analysis of biological material, for example, vegetative bacterial cells, bacterial spores and viruses are provided.

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Research Organization:: SNL-L (Sandia National Laboratories, Livermore, CA (United States))

Sponsoring Organization:: USDOE

DOE Contract Number:: AC04-94AL85000

Assignee:: Sandia National Laboratories (Livermore, CA)

Patent Number(s):: 8,426,135

Application Number:: 13/308,228

OSTI ID:: 1083601

Country of Publication:: United States

Language:: English

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