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Irradiation of strontium chloride targets at proton energies above 35 MeV to produce PET radioisotope Y-86

Journal Article · · Radiochimica Acta
Proton irradiation of natural and enriched SrCl{sub 2} targets was used to produce PET radioisotope {sup 86}. The proton energy was degraded from the incident 117.8 MeV to induce the {sup 88}Sr(p,3n) reaction. For the irradiation three pellets made of {sup nat}SrCl{sub 2} (6.61 and 74.49 g) and {sup 88}SrCl{sub 2} (5.02 g) were pressed and individually encapsulated in stainless steel target bodies. The two smaller targets were irradiated for 0.5-1 h at the energy - 46 {yields} 37 MeV to take advantage of the peak in the excitation function of the {sup 88}Sr(p,3n) reaction. The larger target was irradiated at 66.4 {yields} 44.6 MeV. The irradiated pellets were chemically processed to selectively separate {sup 86}Y radioisotope using Eichrom DGA (N,N,N{prime},N{prime}-tetra-n-octyldiglycolamide) resin. The production yields of {sup 86}Y were determined to be 10-13 mCi/{mu}A h. Coproduction of {sup 87m}Y in the final product was 34% for {sup nat}SrCl{sub 2} and 54% for {sup 88}SrCl{sub 2} target. The chemical separation yield of yttrium reached 88-92%. The developed chemical procedure allows for the same day processing and shipment of the isotope to users.
Research Organization:
BROOKHAVEN NATIONAL LABORATORY (BNL)
Sponsoring Organization:
USDOE SC OFFICE OF SCIENCE (SC)
DOE Contract Number:
AC02-98CH10886
OSTI ID:
1044728
Report Number(s):
BNL--97134-2012-JA; KB0202011
Journal Information:
Radiochimica Acta, Journal Name: Radiochimica Acta Journal Issue: 12 Vol. 99; ISSN 2193-3405
Country of Publication:
United States
Language:
English

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