Nucleic acids, compositions and uses thereof
- Gainesville, FL
- Baltimore, MD
The subject invention provides at least one nucleic acid sequence encoding an aldouronate-utilization regulon isolated from Paenibacillus sp. strain JDR-2, a bacterium which efficiently utilizes xylan and metabolizes aldouronates (methylglucuronoxylosaccharides). The subject invention also provides a means for providing a coordinately regulated process in which xylan depolymerization and product assimilation are coupled in Paenibacillus sp. strain JDR-2 to provide a favorable system for the conversion of lignocellulosic biomass to biobased products. Additionally, the nucleic acid sequences encoding the aldouronate-utilization regulon can be used to transform other bacteria to form organisms capable of producing a desired product (e.g., ethanol, 1-butanol, acetoin, 2,3-butanediol, 1,3-propanediol, succinate, lactate, acetate, malate or alanine) from lignocellulosic biomass.
- Research Organization:
- University of Florida Research Foundation, Inc. (Gainesville, FL)
- Sponsoring Organization:
- USDOE
- DOE Contract Number:
- FC36-00GO10594; FC36-99GO10476
- Assignee:
- University of Florida Research Foundation, Inc. (Gainesville, FL)
- Patent Number(s):
- 8,119,367
- Application Number:
- 12/256,155
- OSTI ID:
- 1036512
- Country of Publication:
- United States
- Language:
- English
Similar Records
Bacterial xylan utilization regulons: systems for coupling depolymerization of methylglucuronoxylans with assimilation and metabolism
Genomic and transcriptomic analysis of carbohydrate utilization by Paenibacillus sp. JDR-2: systems for bioprocessing plant polysaccharides