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Lateral flow devices

Patent ·
OSTI ID:1014656
 [1];  [1];  [2]
  1. Urbana, IL
  2. Champaign, IL
+ Show Author Affiliations
An analytical test for an analyte comprises (a) a base, having a reaction area and a visualization area, (b) a capture species, on the base in the visualization area, comprising nucleic acid, and (c) analysis chemistry reagents, on the base in the reaction area. The analysis chemistry reagents comprise (i) a substrate comprising nucleic acid and a first label, and (ii) a reactor comprising nucleic acid. The analysis chemistry reagents can react with a sample comprising the analyte and water, to produce a visualization species comprising nucleic acid and the first label, and the capture species can bind the visualization species.
Research Organization:
The Board of Trustees of the University of Illinois (Urbana, IL)
Sponsoring Organization:
USDOE
DOE Contract Number:
FG02-01ER63179
Assignee:
The Board of Trustees of the University of Illinois (Urbana, IL)
Patent Number(s):
7,799,554
Application Number:
U S Patent Application 11/686,601
OSTI ID:
1014656
Country of Publication:
United States
Language:
English

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  • Perez, J. Manuel; Simeone, F. Joseph; Saeki, Yoshinaga
  • Journal of the American Chemical Society, Vol. 125, Issue 34, p. 10192-10193 https://doi.org/10.1021/ja036409g
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In vitro selection of self-cleaving DNAs journal December 1996
A highly selective charge transfer fluoroionophore for Cu 2+ journal January 2006
Review of Advanced Liquid−Liquid Extraction Systems for the Separation of Metal Ions by a Combination of Conversion of the Metal Species with Chemical Reaction journal June 2001
Energy Transfer in Aqueous Solutions of Oppositely Charged CdSe/ZnS Core/Shell Quantum Dots and in Quantum Dot−Nanogold Assemblies journal March 2004
Improving Metal Ion Specificity During In Vitro Selection of Catalytic DNA journal June 2002
Molecular Recognition of PNA-Containing Hybrids:  Spontaneous Assembly of Helical Cyanine Dye Aggregates on PNA Templates journal March 1999
Bivalent Cholesterol-Based Coupling of Oligonucletides to Lipid Membrane Assemblies journal August 2004
The Chemical Form of Mercury in Fish journal August 2003
Gold Mining as a Source of Mercury Exposure in the Brazilian Amazon journal May 1998
Functional DNA nanotechnology: emerging applications of DNAzymes and aptamers journal December 2006
Determination of cadmium, mercury and lead in seawater by electrothermal vaporization isotope dilution inductively coupled plasma mass spectrometry journal September 1999
RNA aptamers to the adenosine moiety of S-adenosyl methionine: structural inferences from variations on a theme and the reproducibility of SELEX journal May 1997
MR imaging of splenic metastases: ferrite-enhanced detection in rats journal October 1987
Lead cleavage sites in the core structure of group I intron-RNA journal January 1993
Isolation and characterization of fluorophore-binding RNA aptamers journal November 1998
One-Step, Room Temperature, Colorimetric Detection of Mercury (Hg 2+ ) Using DNA/Nanoparticle Conjugates journal March 2008
Sequence-specific Peptide Aptamers, Interacting with the Intracellular Domain of the Epidermal Growth Factor Receptor, Interfere with Stat3 Activation and Inhibit the Growth of Tumor Cells journal July 2003
Label-Free Electrochemical Detection for Aptamer-Based Array Electrodes journal August 2005
Sequence-Encoded Self-Assembly of Multiple-Nanocomponent Arrays by 2D DNA Scaffolding journal December 2005
Nucleic Acid Nanostructures and Topology journal December 1998
Novel Monoclonal Antibodies with Specificity for Chelated Uranium(VI):  Isolation and Binding Properties journal September 2004
Desperately seeking sensors journal July 1995
In Vivo Monitoring of Mercury Ions Using a Rhodamine-Based Molecular Probe journal November 2006
Novel gold-dithiol nano-networks with non-metallic electronic properties journal September 1995
A general purpose RNA-cleaving DNA enzyme journal April 1997
Highly Selective and Sensitive Phosphane Sulfide Derivative for the Detection of Hg 2+ in an Organoaqueous Medium journal March 2007
Circuits and programmable self-assembling DNA structures journal September 2002
Colorimetric Biosensors Based on DNAzyme-Assembled Gold Nanoparticles journal July 2004
The Ternary Systems Ethylene Glycol–Potassium Carbonate–Water and Dioxane–Potassium Carbonate–Water. journal May 1940
A DNA enzyme that cleaves RNA journal December 1994
Determination of Picomolar Concentrations of Metal Ions Using Fluorescence Anisotropy:  Biosensing with a “Reagentless” Enzyme Transducer journal November 1998
Crystal Structure of the Leadzyme at 1.8 Å Resolution:  Metal Ion Binding and the Implications for Catalytic Mechanism and Allo Site Ion Regulation † journal August 2003
Ordering of Quantum Dots Using Genetically Engineered Viruses journal May 2002
Environmental Copper: its Dynamics and Human Exposure Issues journal October 2001
Cu 2+ -Induced Blue Shift of the Pyrene Excimer Emission:  A New Signal Transduction Mode of Pyrene Probes journal March 2001
H-DNA and Related Structures journal June 1994
Molecular Aptamer Beacons for Real-Time Protein Recognition journal March 2002
Randomization of genes by PCR mutagenesis. journal August 1992
A Lead-Dependent DNAzyme with a Two-Step Mechanism † journal June 2003
Design of a Molecular Beacon DNA Probe with Two Fluorophores journal January 2001
Thrombin-binding DNA aptamer forms a unimolecular quadruplex structure in solution. journal April 1993
Reagentless, Reusable, Ultrasensitive Electrochemical Molecular Beacon Aptasensor journal January 2006
Smart Nanomaterials Responsive to Multiple Chemical Stimuli with Controllable Cooperativity journal July 2006
A selective and sensitive chemosensor for Cu2+ based on 8-hydroxyquinoline journal April 2006
RNA pseudoknots that inhibit human immunodeficiency virus type 1 reverse transcriptase. journal August 1992
A new strategy for attachment of antibodies to sterically stabilized liposomes resulting in efficient targeting to cancer cells journal July 1995
Estimating the Contribution of Lead-Based Paint to Soil Lead, Dust Lead, and Childhood Blood Lead
  • Marcus, A. H.; Elias, R. W.
  • Lead in Paint, Soil and Dust: Health Risks, Exposure Studies, Control Measures, Measurement Methods, and Quality Assurance https://doi.org/10.1520/STP12963S
book
The crystal structure of an AII-RNAhammerhead ribozyme: A proposed mechanism for RNA catalytic cleavage journal June 1995
Simultaneous detection of diverse analytes with an aptazyme ligase array journal January 2003
Oligonucleotide-Based Fluorescence Probe for Sensitive and Selective Detection of Mercury(II) in Aqueous Solution journal May 2008
In vitro selection of an allosteric ribozyme that transduces analytes to amplicons journal January 1999
Single-Molecule Measurements of Gold-Quenched Quantum Dots journal October 2004
Redox Switchable Fluorescent Probe Selective for Either Hg(II) or Cd(II) and Zn(II) journal June 1999
Wavelength-shifting molecular beacons journal November 2000
A New Fluorescent Chemosensor for Copper Ions Based on Tripeptide Glycyl−Histidyl−Lysine (GHK) journal October 2001
Smart Nanomaterials Inspired by Biology: Dynamic Assembly of Error-Free Nanomaterials in Response to Multiple Chemical and Biological Stimuli journal May 2007
Homocysteine-Mediated Reactivity and Assembly of Gold Nanoparticles journal January 2007
Selective extraction of gold(III) in the presence of Pd(II) and Pt(IV) by salting-out of the mixture of 2-propanol and water journal November 2002
Recovery of penicillin G from fermentation broth with reactive extraction in a mixer-settler journal April 1987
In Vitro Selection of Functional Nucleic Acids journal June 1999
Two Decades of RNA Catalysis journal September 2002
Porphyrin Metalation Catalyzed by a Small RNA Molecule journal January 1996
Highly selective ratiometric fluorescent sensor for Cu(II) with two urea groups journal April 2006
Sequential Self-Assembly of a DNA Hexagon as a Template for the Organization of Gold Nanoparticles journal March 2006
In vitro selection of hematoporphyrin binding DNA aptamers journal December 2000
Fossil Fuels as a Source of Mercury Pollution journal June 1971
In vitro selection of DNA aptamers to anthrax spores with electrochemiluminescence detection journal May 1999
Structural diversity of self-cleaving ribozymes journal May 2000
Molecular Aptamer for Real-Time Oncoprotein Platelet-Derived Growth Factor Monitoring by Fluorescence Anisotropy journal December 2001
Determination of lead in microliter amounts of whole blood by stripping potentiometry journal April 1994
Manual Manufacturing of Oligonucleotide, DNA, and Protein Microchips journal August 1997
In vitro selection of molecular beacons journal October 2003
What Controls the Optical Properties of DNA-Linked Gold Nanoparticle Assemblies? journal May 2000
Controlling Gene Expression in Living Cells Through Small Molecule-RNA Interactions journal October 1998
Colorimetric detection of DNA sequences based on electrostatic interactions with unmodified gold nanoparticles journal September 2004
Three-dimensional structure of a hammerhead ribozyme journal November 1994
Inhibition of receptor binding by high-affinity RNA ligands to vascular endothelial growth factor journal August 1994
Combination with liposome-entrapped, ends-modified raf antisense oligonucleotide (LErafAON) improves the anti-tumor efficacies of cisplatin, epirubicin, mitoxantrone, docetaxel and gemcitabine journal January 2004
Fluorescence Polarization for Monitoring Ribozyme Reactions in Real Time journal August 2000
Magnetic Sensors for Protease Assays journal March 2003
Mercury II -Mediated Formation of Thymine−Hg II −Thymine Base Pairs in DNA Duplexes journal February 2006
DNA-Templated Self-Assembly of Protein Arrays and Highly Conductive Nanowires journal September 2003
Pharmacokinetics and Biodistribution of Novel Aptamer Compositions journal December 2004
Cleaving DNA with DNA journal March 1998
Systematic Evolution of a DNA Aptamer Binding to Rat Brain Tumor Microvessels: SELECTIVE TARGETING OF ENDOTHELIAL REGULATORY PROTEIN PIGPEN journal February 2001
Site-specific cleavage reaction catalyzed by leadzyme is enhanced by combined effect of lead and rare earth ions journal September 1996
Laser-mediated, site-specific inactivation of RNA transcripts journal May 1999
In Vitro Selection Analysis of Neomycin Binding RNAs with a Mutagenized Pool of Variants of the 16S rRNA Decoding Region † journal January 1996
Modulation of DNA Constraints That Control Macromolecular Folding journal March 2006
The study of the gas—solid interaction of acetic acid with a cuprous oxide surface using reflection—absorption spectroscopy journal December 1974
DNA-Templated Self-Assembly of Metallic Nanocomponent Arrays on a Surface journal October 2004
A DNA Aptamer That Binds Adenosine and ATP journal January 1995
Differential Conjugation of Tat Peptide to Superparamagnetic Nanoparticles and Its Effect on Cellular Uptake journal July 2002
Aptamers as therapeutic and diagnostic agents journal March 2000
Isolation of a fluorophore-specific DNA aptamer with weak redox activity journal November 1998
In vitro selection of RNA aptamers specific for cyanocobalamin journal February 1994
Defining a Smaller RNA Substrate for Elongation Factor Tu journal February 1995
Selection of peptides with semiconductor binding specificity for directed nanocrystal assembly journal June 2000
A “Turn-On” Fluorescent Sensor for the Selective Detection of Mercuric Ion in Aqueous Media journal November 2003
2′-Fluoropyrimidine RNA-based Aptamers to the 165-Amino Acid Form of Vascular Endothelial Growth Factor (VEGF 165 ) : INHIBITION OF RECEPTOR BINDING AND VEGF-INDUCED VASCULAR PERMEABILITY THROUGH INTERACTIONS REQUIRING THE EXON 7-ENCODED DOMAIN journal August 1998
Controlled Nucleation for the Regulation of the Particle Size in Monodisperse Gold Suspensions journal January 1973
Covalent DNA-Streptavidin Conjugates as Building Blocks for Novel Biometallic Nanostructures journal September 1998
Light-generated oligonucleotide arrays for rapid DNA sequence analysis. journal May 1994
N,N-Bis(α-iodoacetyl)-2,2′-dithiobis(ethylamine), a reversible crosslinking reagent for protein sulfhydryl groups journal October 1981
pH-Controlled Reversible Assembly of Peptide-Functionalized Gold Nanoparticles † journal January 2007
Oligonucleotide Inhibitors of P-Selectin-Dependent Neutrophil-Platelet Adhesion journal August 1998
RNA catalysis journal December 1998
Hemin-Stimulated Docking of Cytochrome c to a Hemin−DNA Aptamer Complex † journal April 2002
Targeted nanoparticle-aptamer bioconjugates for cancer chemotherapy in vivo journal April 2006
Identification of two novel arginine binding DNAs. journal December 1995
Rational design of allosteric ribozymes journal June 1997
A Simple and Sensitive “Dipstick” Test in Serum Based on Lateral Flow Separation of Aptamer-Linked Nanostructures journal December 2006
Sequence Symmetry as a Tool for Designing DNA Nanostructures journal October 2005
Magnetic Nanosensors for the Detection of Oligonucleotide Sequences journal September 2001
A Series of Polyamide Receptor Based PET Fluorescent Sensor Molecules:  Positively Cooperative Hg 2+ Ion Binding with High Sensitivity journal August 2006
Oligonucleotide aptamers that recognize small molecules journal June 1999
Liposome-Anchored Vascular Endothelial Growth Factor Aptamers § journal September 1998
Selection in vitro of single-stranded DNA molecules that fold into specific ligand-binding structures journal February 1992
Dissociation of Long-Chain Duplex RNA Can Occur Via Strand Displacement in Vitro: Biological Implications journal November 1996
Potentiometric determination of acid dissociation constants (pKa) for human and veterinary antibiotics journal July 2004
Pseudohexagonal 2D DNA Crystals from Double Crossover Cohesion journal August 2004
Exploiting Polypeptide Motifs for the Design of Selective Cu(II) Ion Chemosensors journal January 1998
Structural probing and damage selection of citrullineand arginine-specific RNA aptamers identify base positions required for binding journal January 1995
DNA Aptamer Folding on Gold Nanoparticles:  From Colloid Chemistry to Biosensors journal March 2008
Proofreading and Error Removal in a Nanomaterial Assembly journal November 2005
Programmed Assembly of DNA Functionalized Quantum Dots journal September 1999
Optical Sensors Based on Hybrid Aptamer/Conjugated Polymer Complexes journal February 2004
Role of Nd 3+ and Pb 2+ on the RNA Cleavage Reaction by a Small Ribozyme † journal March 1997
A DNA-based method for rationally assembling nanoparticles into macroscopic materials journal August 1996
An RNA motif that binds ATP journal August 1993
Macrophage Imaging in Central Nervous System and in Carotid Atherosclerotic Plaque Using Ultrasmall Superparamagnetic Iron Oxide in Magnetic Resonance Imaging journal January 2004
Tuning the Sensitivity of a Foldamer-Based Mercury Sensor by Its Folding Energy journal August 2006
Relaxometric and Magnetic Characterization of Ultrasmall Iron Oxide Nanoparticles with High Magnetization. Evaluation as Potential T 1 Magnetic Resonance Imaging Contrast Agents for Molecular Imaging journal April 2007
Integrated Nanoparticle-Biomolecule Hybrid Systems: Synthesis, Properties, and Applications journal November 2004
Simple and Rapid Colorimetric Biosensors Based on DNA Aptamer and Noncrosslinking Gold Nanoparticle Aggregation journal May 2007
Light-switching excimer probes for rapid protein monitoring in complex biological fluids journal November 2005
A Novel Acidophilic RNA Motif That Recognizes Coenzyme A † journal March 1998
Detection of Heavy Metals by Immunoassay:  Optimization and Validation of a Rapid, Portable Assay for Ionic Cadmium journal January 1998
Synthesis from DNA of a molecule with the connectivity of a cube journal April 1991
Hg 2+ -Selective OFF−ON and Cu 2+ -Selective ON−OFF Type Fluoroionophore Based upon Cyclam journal February 2006
Designed Signaling Aptamers that Transduce Molecular Recognition to Changes in Fluorescence Intensity journal March 2000
DNA aptamers that bind to chitin journal March 2000
Atomic force microscopy of oriented linear DNA molecules labeled with 5nm gold spheres journal January 1993
Selection of novel Mg(2+)-dependent self-cleaving ribozymes. journal September 1995
Improving Fluorescent DNAzyme Biosensors by Combining Inter- and Intramolecular Quenchers journal December 2003
Folding DNA to create nanoscale shapes and patterns journal March 2006
Hammerhead ribozyme kinetics journal August 1998
Extraction of Oxidized and Reduced Forms of Uranium from Contaminated Soils:  Effects of Carbonate Concentration and pH journal June 2005
2-Aza-1,3-butadiene Derivatives Featuring an Anthracene or Pyrene Unit:  Highly Selective Colorimetric and Fluorescent Signaling of Cu 2+ Cation journal July 2006
Smart “Turn-on” Magnetic Resonance Contrast Agents Based on Aptamer-Functionalized Superparamagnetic Iron Oxide Nanoparticles journal September 2007
Accumulation of Ultrasmall Superparamagnetic Particles of Iron Oxide in Human Atherosclerotic Plaques Can Be Detected by In Vivo Magnetic Resonance Imaging journal May 2003
The Structural Basis of Ribosome Activity in Peptide Bond Synthesis journal August 2000
High-Efficiency Intracellular Magnetic Labeling with Novel Superparamagnetic-Tat Peptide Conjugates journal March 1999
RNA aptamers as reversible antagonists of coagulation factor IXa journal September 2002
Electrothermal isotope dilution inductively coupled plasma mass spectrometry method for the determination of sub-ng ml –1 levels of lead in human plasma journal January 1994
Determination of the orientation of adsorbed molecules at solid-liquid interfaces by thin-layer electrochemistry: aromatic compounds at platinum electrodes journal May 1982
Capillary Optode: Determination of Mercury(II) in Aqueous Solution journal January 1999
A colorimetric sensor array for odour visualization journal August 2000
Synthesis, Structure, and Properties of Model Organic Surfaces journal October 1992
Rapid Aggregation of Gold Nanoparticles Induced by Non-Cross-Linking DNA Hybridization journal July 2003
Rational Design of “Turn-On” Allosteric DNAzyme Catalytic Beacons for Aqueous Mercury Ions with Ultrahigh Sensitivity and Selectivity journal October 2007
A Highly Selective Fluorescent Chemosensor for Lead Ions journal June 2002
Nucleic acid nanostructures: bottom-up control of geometry on the nanoscale journal December 2004
A tetracycline-binding RNA aptamer journal October 2001
Directed Evolution of Nucleic Acid Enzymes journal June 2004
A Long-Wavelength Fluorescent Chemodosimeter Selective for Cu(II) Ion in Water journal August 1997
Capping DNA with DNA † journal March 2000
Aptamer-Functionalized Au Nanoparticles for the Amplified Optical Detection of Thrombin journal September 2004
Direct detection of antibody-antigen binding using an on-chip artificial pore journal January 2003
In vitro selection of RNA lectins: using combinatorial chemistry to interpret ribozyme evolution journal May 1995
Evolution in vitro of an RNA enzyme with altered metal dependence journal January 1993
Highly Dispersible Molecular Sieve Carbon Nanoparticles journal November 2004
Functionalization and peptide-based delivery of magnetic nanoparticles as an intracellular MRI contrast agent journal June 2004
Bioconjugated Nanoparticles for DNA Protection from Cleavage journal June 2003
Exploiting the Self-Assembly Strategy for the Design of Selective CuII Ion Chemosensors journal October 1999
An Aptamer-Based Quartz Crystal Protein Biosensor journal September 2002
Interaction of retroviral nucleocapsid proteins with transfer RNAPhe: a lead ribozyme and 1H NMR study journal September 1996
Low viscosity organic modifiers in reversed-phase HPLC journal May 1985
Aptamer-Based Colorimetric Probe for Cocaine journal August 2002
Peptidyl chemosensors incorporating a fret mechanism for detection of Ni(II) journal August 1998
DNA enzymes journal January 1998
Ternary Systems: Water, Tertiary Butanol and Salts at 30° journal June 1930
A novel strategy for selection of allosteric ribozymes yields RiboReporterTM sensors for caffeine and aspartame journal March 2004
Photoactive chemosensors 4: a Cu2+ protein cavity mimicking fluorescent chemosensor for selective Cu2+ recognition journal June 2004
A [RuII(bipy)3]-[1,9-diamino-3,7-diazanonane-4,6-dione] two-component system, as an efficient ON–OFF luminescent chemosensor for Ni2+ and Cu2+ in water, based on an ET (energy transfer) mechanism journal January 1999
Selection and design of high-affinity rna ligands for hiv-1 rev journal December 1993
Graphite furnace atomic absorption spectroscopic measurement of blood lead in matrix-matched standards journal September 1994
An extended Johnson–Furter equation to salting-out phase separation of aqueous solution of water-miscible organic solvents journal December 2001
A General Strategy for Effector-mediated Control of RNA-cleaving Ribozymes and DNA Enzymes journal April 2002
RNA Molecules That Specifically and Stoichiometrically Bind Aminoglycoside Antibiotics with High Affinities † journal January 1996
A closed tube format for amplification and detection of DNA based on energy transfer journal June 1997
Introduction of reporter groups at specific sites in DNA containing phosphorothioate diesters journal December 1989
Salting-out solvent extraction for preconcentration of neutral polar organic solutes from water journal July 1990
A DNA aptamer which binds to and inhibits thrombin exhibits a new structural motif for DNA journal March 1993
Inhibitory DNA Ligands to Platelet-Derived Growth Factor B-Chain journal January 1996
Amplified electrochemical detection of DNA through the aggregation of Au nanoparticles on electrodes and the incorporation of methylene blue into the DNA-crosslinked structure journal January 2007
Multiplex detection of four pathogenic retroviruses using molecular beacons journal May 1999
Ratiometric and Selective Fluorescent Sensor for Cu II Based on Internal Charge Transfer (ICT) journal March 2005
Isolation of high-affinity GTP aptamers from partially structured RNA libraries journal August 2002
What Controls the Melting Properties of DNA-Linked Gold Nanoparticle Assemblies? journal February 2003
The influence of the blood levels of lead, aluminum and vanadium upon the arterial hypertension journal January 1995
Use of Magnetic Beads in Selection and Detection of Biotoxin Aptamers by Electrochemiluminescence and Enzymatic Methods journal January 2002
Adapting Selected Nucleic Acid Ligands (Aptamers) to Biosensors journal August 1998
Rapid identification and characterization of hammerhead-ribozyme inhibitors using fluorescence-based technology journal January 2001
Simple and sensitive aptamer-based colorimetric sensing of protein using unmodified gold nanoparticle probes journal January 2007
New fluorescent and colorimetric DNAzyme biosensors for metal ions journal July 2003
Engineering DNA aptamers and DNA enzymes with fluorescence-signaling properties journal January 2004
Potent 2'-Amino-2'-deoxypyrimidine RNA Inhibitors of Basic Fibroblast Growth Factor journal September 1995
In vitro selection of RNA molecules that bind specific ligands journal August 1990
Review: Environmental exposure to mercury and its toxicopathologic implications for public health journal January 2003
A general approach for the use of oligonucleotide effectors to regulate the catalysis of RNA-cleaving ribozymes and DNAzymes journal April 2002
Bifunctional recombinant proteins in cancer therapy: cell penetrating peptide aptamers as inhibitors of growth factor signaling journal December 2003
Mass-Produced Ionophore-Based Fluorescent Microspheres for Trace Level Determination of Lead Ions journal October 2002
Activity Coefficients of Nonelectrolyte Solutes in Aqueous Salt Solutions. journal August 1952
Isolation of new ribozymes from a large pool of random sequences [see comment] journal September 1993
Self-Assembling a Molecular Pegboard journal December 2005
The Structure of Alpha-Thrombin Inhibited by a 15-MER Single-Stranded DNA Aptamer report May 1993
Small-Molecule Screening Made Simple for a Difficult Target with a Signaling Nucleic Acid Aptamer that Reports on Deaminase Activity journal August 2006
Quantum dot bioconjugates for imaging, labelling and sensing journal June 2005
Aptamer-Directed Self-Assembly of Protein Arrays on a DNA Nanostructure journal July 2005
Activity of amphipathic poly(ethylene glycol) 5000 to prolong the circulation time of liposomes depends on the liposome size and is unfavorable for immunoliposome binding to target journal February 1991
DNAzymes: From Creation In Vitro to Application In Vivo journal August 2004
Calcium-dependent oligonucleotide antagonists specific for L-selectin. journal June 1996
Size Control, Metal Substitution, and Catalytic Application of Cryptomelane Nanomaterials Prepared Using Cross-linking Reagents journal January 2004
Atomic Absorption Spectrometric and Spectrophotometric Trace Analysis of Uranium in Environmental Samples with N-p-MEthoxyphenyl-2-Furylacrylohydroxamic acid and 4-(2-Pyridylazo) Resorcinol journal July 1989
Hexaphyrin(1.0.1.0.0.0). A new colorimetric actinide sensor journal November 2004
Accelerated Color Change of Gold Nanoparticles Assembled by DNAzymes for Simple and Fast Colorimetric Pb 2+ Detection journal October 2004
Tat peptide-derivatized magnetic nanoparticles allow in vivo tracking and recovery of progenitor cells journal April 2000
Selective optimization of the Rev-binding element of HIV-1 journal January 1993
DNA Probes Using Fluorescence Resonance Energy Transfer (FRET): Designs and Applications journal November 2001
Fluorescent detection of zinc in biological systems: recent development on the design of chemosensors and biosensors journal January 2004
High-Density, Covalent Attachment of DNA to Silicon Wafers for Analysis by MALDI-TOF Mass Spectrometry journal July 1997
A Colorimetric Lead Biosensor Using DNAzyme-Directed Assembly of Gold Nanoparticles journal June 2003
A scaled particle theory of aqueous and nonaqueous solutions journal December 1976
Cytosolic drug delivery using pH- and light-sensitive liposomes journal August 1999
Isolation of virus-neutralizing RNAs from a large pool of random sequences. journal December 1995
In vitro selection of aptamers that act with Zn2+ journal November 2000
Normal T-cell response and in vivo magnetic resonance imaging of T cells loaded with HIV transactivator-peptide-derived superparamagnetic nanoparticles journal October 2001
Molecular Recognition of Amino Acids by RNA-Aptamers: An L-Citrulline Binding RNA Motif and Its Evolution into an L-Arginine Binder journal March 1994
A Fluorescent Zinc Probe Based on Metal-Induced Peptide Folding journal January 1996
Effect of substrate RNA sequence on the cleavage reaction by a short ribozyme journal December 1998
Fluorescent and Photochemical Probes of Dynamic Biochemical Signals inside Living Cells book October 1993
RNA aptamers to the peptidyl transferase inhibitor chloramphenicol journal November 1997
Metal-Based Turn-On Fluorescent Probes for Sensing Nitric Oxide journal January 2007
Aptamer Beacons for the Direct Detection of Proteins journal July 2001
The risk of lead toxicity in homes with lead paint hazard journal February 1991
Design of an Emission Ratiometric Biosensor from MerR Family Proteins:  A Sensitive and Selective Sensor for Hg 2+ journal March 2007
Adenine-Aptamer Complexes: A BIPARTITE RNA SITE THAT BINDS THE ADENINE NUCLEIC BASE journal November 2001
Quantum-Dot/Aptamer-Based Ultrasensitive Multi-Analyte Electrochemical Biosensor journal February 2006
Aptamers: An Emerging Class of Molecules That Rival Antibodies in Diagnostics journal September 1999
An Autonomous DNA Nanomotor Powered by a DNA Enzyme journal July 2004
MATERIALS SCIENCE: Nucleic Acid Nanotechnology journal December 2004
Investigation of Fatty Acid Monolayers on Metals by Contact Potential Measurements 1 journal March 1965
Mirror-design of L-oligonucleotide ligands binding to L-arginine journal September 1996
Synthesis of New Phenanthroline-Based Heteroditopic Ligands – Highly Efficient and Selective Fluorescence Sensors for Copper(II) Ions journal November 2006
Selected classes of minimised hammerhead ribozyme have very high cleavage rates at low Mg2+ concentration journal January 1999
Linear assemblies of nanoparticles electrostatically organized on DNA scaffolds journal March 2003
Automated synthesis of double dye-labeled oligonucleotides using tetramethylrhodamine (TAMRA) solid supports journal August 1997
Penetration-controlled reactions in organized monolayer assemblies. 1. Aqueous permanganate interaction with monolayer and multilayer films of long-chain surfactants journal November 1987
Mercury toxicity in the pregnant woman, fetus, and newborn infant journal October 1976
A Novel Potassium Sensing in Aqueous Media with a Synthetic Oligonucleotide Derivative. Fluorescence Resonance Energy Transfer Associated with Guanine Quartet−Potassium Ion Complex Formation journal December 2002
In vitro evolution of nucleic acids journal June 1994
A new DNA nanostructure, the G-wire, imaged by scanning probe microscopy journal January 1995
Crystal Structure of Unmodified tRNAGln Complexed with Glutaminyl-tRNA Synthetase and ATP Suggests a Possible Role for Pseudo-Uridines in Stabilization of RNA Structure journal June 1994
Mercury: major issues in environmental health. journal April 1993
DNA Conformational Switches as Sensitive Electronic Sensors of Analytes journal May 2002
15 N− 15 N J -Coupling Across Hg II :  Direct Observation of Hg II -Mediated T−T Base Pairs in a DNA Duplex journal January 2007
DNAzyme amplification of molecular beacon signal journal September 2005
Functional Requirements for Specific Ligand Recognition by a Biotin-Binding RNA Pseudoknot † journal October 1998
DNA aptamers and DNA enzymes journal June 1997
Mechanism and Utility of an RNA-Cleaving DNA Enzyme † journal September 1998
Isolation of RNA Aptamers for Biological Cofactors by In Vitro Selection journal June 1994
Mutagenic PCR. journal June 1994
Interactions of uranium and thorium with arsenazo III in an aqueous medium journal April 1997
Highly Selective Chromogenic and Redox or Fluorescent Sensors of Hg 2+ in Aqueous Environment Based on 1,4-Disubstituted Azines journal November 2005
Colorimetric Detection of Mercuric Ion (Hg2+) in Aqueous Media using DNA-Functionalized Gold Nanoparticles journal May 2007
Aptamers as potential nucleic acid pharmaceuticals book January 1995
DNA-Templated Self-Assembly of Two-Dimensional and Periodical Gold Nanoparticle Arrays journal January 2006
Fluorescent Sensors Based on Aptamer Self-Assembly journal November 2000
Structural basis of DNA folding and recognition in an AMP-DNA aptamer complex: distinct architectures but common recognition motifs for DNA and RNA aptamers complexed to AMP journal November 1997
Antibody Targeting of Long-Circulating Lipidic Nanoparticles Does Not Increase Tumor Localization but Does Increase Internalization in Animal Models journal July 2006
New Transition-Metal-Dependent DNAzymes as Efficient Endonucleases and as Selective Metal Biosensors journal October 2002
Design and Evaluation of a Peptidyl Fluorescent Chemosensor for Divalent Zinc journal January 1996
Crystal structure of a four-stranded intercalated DNA: d(C4) journal November 1994
Quadruplex structure of Oxytricha telomeric DNA oligonucleotides journal March 1992
A Gold Nanoparticle-Based Aptamer Target Binding Readout for ATP Assay journal November 2007
Allosteric selection of ribozymes that respond to the second messengers cGMP and cAMP
  • Breaker, Ronald R.; Koizumi, Makoto; Soukup, Garrett A.
  • Nature Structural Biology, Vol. 6, Issue 11, p. 1062-1071 https://doi.org/10.1038/14947
journal November 1999
Turn-On and Ratiometric Mercury Sensing in Water with a Red-Emitting Probe journal May 2007
Pharmacokinetics and biodistribution of the camptothecin–polymer conjugate IT-101 in rats and tumor-bearing mice journal August 2005
Rapid Chiral Assembly of Rigid DNA Building Blocks for Molecular Nanofabrication journal December 2005
Quantum-Dot Aptamer Beacons for the Detection of Proteins journal October 2005
Label-Free Colorimetric Detection of Specific Sequences in Genomic DNA Amplified by the Polymerase Chain Reaction journal September 2004
Properties of an In vitro Selected Pb2+ Cleavage Motif journal October 1994
SURVEY AND SUMMARY: Recent advances in the elucidation of the mechanisms of action of ribozymes journal May 2001
A DNA enzyme with Mg2+-dependent RNA phosphoesterase activity journal October 1995
Imaging DNA molecules on mica surface by atomic force microscopy in air and in liquid journal January 2005
Aptamer-Based Folding Fluorescent Sensor for Cocaine journal May 2001
Quenching of CdSe quantum dot emission, a new approach for biosensing journal January 2005
Phosphorylating DNA with DNA journal March 1999
Characterization of a DNA-Cleaving deoxyribozyme journal October 2001
A fast, simple and reliable method for the microdetermination of phosphorus in biological materials journal February 1964
In vitro selection of aptamers: the dearth of pure reason journal June 1996
Targeting of ultrasmall superparamagnetic iron oxide (USPIO) particles to tumor cellsin Vivo by using transferrin receptor pathways journal August 1998
p-Dimethylaminobenzaldehyde thiosemicarbazone: A simple novel selective and sensitive fluorescent sensor for mercury(II) in aqueous solution journal March 2006
Spectral characterization of a newly synthesized fluorescent semicarbazone derivative and its usage as a selective fiber optic sensor for copper(II) journal February 2007
A Selective and Sensitive Fluoroionophore for Hg II , Ag I , and Cu II with Virtually Decoupled Fluorophore and Receptor Units journal February 2000
Chemical Properties of Water-Miscible Solvents Separated by Salting-out and Their Application to Solvent Extraction. journal January 1994
Spontaneously organized molecular assemblies. 3. Preparation and properties of solution adsorbed monolayers of organic disulfides on gold surfaces journal April 1987
Preparation of aptamer-linked gold nanoparticle purple aggregates for colorimetric sensing of analytes journal June 2006
Mfold web server for nucleic acid folding and hybridization prediction journal July 2003
A specific quadrilateral synthesized from DNA branched junctions journal August 1989
Structural Analysis of Metal Ion Ligation to Nucleotides and Nucleic Acids Using Pulsed EPR Spectroscopy journal February 2002
Signaling Aptamers for Monitoring Enzymatic Activity and for Inhibitor Screening journal August 2004
Spectroscopic Evidence for Inner-Sphere Coordination of Metal Ions to the Active Site of a Hammerhead Ribozyme journal May 1998
Real-Time Characterization of Ribozymes by Fluorecence Resonance Energy Transfer (FRET) journal May 1999
A catalytic DNA for porphyrin metallation journal September 1996
A Mammalian Expression Vector for Expression and Purification of Secreted Proteins for Structural Studies journal December 2000
In vitro selection and characterization of a highly efficient Zn(II)-dependent RNA-cleaving deoxyribozyme journal January 2000
The Ca2+ Ion as a Cofactor for a Novel RNA-Cleaving Deoxyribozyme journal December 1996
A Combinatorial Approach To Discover New Chelators for Optical Metal Ion Sensing journal November 2000
Six-Helix Bundles Designed from DNA journal April 2005

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