Insulator-based DEP with impedance measurements for analyte detection

Davalos, Rafael V; Simmons, Blake A; Crocker, Robert W; Cummings, Eric B

Insulator-based DEP with impedance measurements for analyte detection

Patent · Tue Mar 16 04:00:00 EDT 2010

OSTI ID:1014491

Davalos, Rafael V ^[1]; Simmons, Blake A ^[2]; Crocker, Robert W ^[3]; Cummings, Eric B ^[4]

Blacksburg, VA
San Francisco, CA
Fremont, CA
Livermore, CA

Disclosed herein are microfluidic devices for assaying at least one analyte specie in a sample comprising at least one analyte concentration area in a microchannel having insulating structures on or in at least one wall of the microchannel which provide a nonuniform electric field in the presence of an electric field provided by off-chip electrodes; and a pair of passivated sensing electrodes for impedance detection in a detection area. Also disclosed are assay methods and methods of making.

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Research Organization:: Sandia Corporation (Livermore, CA)

Sponsoring Organization:: USDOE

DOE Contract Number:: AC04-94AL85000

Assignee:: Sandia Corporation (Livermore, CA)

Patent Number(s):: 7,678,256

Application Number:: US Patent Application 11/556,685

OSTI ID:: 1014491

Country of Publication:: United States

Language:: English

References (16)

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