Preconcentration and separation of analytes in microchannels

Hatch, Anson; Singh, Anup K; Herr, Amy E; Throckmorton, Daniel J

Preconcentration and separation of analytes in microchannels

Patent · 09 November 2010

OSTI ID:1014940

Hatch, Anson ^[1]; Singh, Anup K ^[2]; Herr, Amy E ^[3]; Throckmorton, Daniel J ^[1]

Tracy, CA
Danville, CA
Fremont, CA

Disclosed herein are methods and devices for preconcentrating and separating analytes such as proteins and polynucleotides in microchannels. As disclosed, at least one size-exclusion polymeric element is adjacent to processing area or an assay area in a microchannel which may be porous polymeric element. The size-exclusion polymeric element may be used to manipulate, e.g. concentrate, analytes in a sample prior to assaying in the assay area.

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Research Organization:: Sandia Corporation (Livermore, CA)

Sponsoring Organization:: USDOE

DOE Contract Number:: AC04-94AL85000

Assignee:: Sandia Corporation (Livermore, CA)

Patent Number(s):: 7,828,948

Application Number:: US Patent Application 11/536,753

OSTI ID:: 1014940

Country of Publication:: United States

Language:: English

References (33)

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