V79 survival following simultaneous or sequential irradiation by 14. 8-MeV neutrons and /sup 60/Co photons
A unique tandem source irradiation facility, comprised of an intense d-T neutron source and a /sup 60/Co teletherapy unit, has been used to investigate biological response for different neutron/photon configurations. V79 Chinese hamster cells, attached as monolayers in log phase growth, were irradiated at 37/sup 0/C by either 14.8 MeV neutrons, /sup 60/Co or by a mixture of 40% neutrons - 60% photons in simultaneous or sequential application. Measurements of cell survival indicate an increased effectiveness in cell killing for simultaneously administered neutrons and photons than was measured or predicted for sequentially applied beam modalities. An understanding of the magnitude of these interactive effects is important both for calculating accurate effective doses for neutron radiotherapy of deep-seated tumors, for which the photon component is appreciable and for determination of environmental hazards to people occupationally exposed to low levels of photons and neutrons.
- Research Organization:
- Wisconsin Univ., Madison (USA)
- DOE Contract Number:
- AS02-76EV01105
- OSTI ID:
- 5475648
- Report Number(s):
- DOE/EV/01105-282; ON: DE82009365; TRN: 82-011836
- Country of Publication:
- United States
- Language:
- English
Similar Records
V79 survival following simultaneous or sequential irradiation by 15-MeV neutrons and /sup 60/Co photons
Comments on ''V79 survival following simultaneous or sequential irradiation by 15-MeV neutrons and /sup 60/Co photons'' by Higgins et al. (Radiat. Res. 95, 45-56(1983))
Related Subjects
62 RADIOLOGY AND NUCLEAR MEDICINE
11 NUCLEAR FUEL CYCLE AND FUEL MATERIALS
ANIMAL CELLS
BIOLOGICAL RADIATION EFFECTS
IRRADIATION PROCEDURES
RADIOSENSITIVITY EFFECTS
CELL CULTURES
COBALT 60
FAST NEUTRONS
GAMMA RADIATION
IRRADIATION
LOW DOSE IRRADIATION
MEV RANGE 10-100
RADIOTHERAPY
SURVIVAL TIME
BARYONS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOLOGICAL EFFECTS
COBALT ISOTOPES
ELECTROMAGNETIC RADIATION
ELEMENTARY PARTICLES
ENERGY RANGE
FERMIONS
HADRONS
INTERMEDIATE MASS NUCLEI
INTERNAL CONVERSION RADIOISOTOPES
IONIZING RADIATIONS
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
MEDICINE
MEV RANGE
MINUTES LIVING RADIOISOTOPES
NEUTRONS
NUCLEAR MEDICINE
NUCLEI
NUCLEONS
ODD-ODD NUCLEI
RADIATION EFFECTS
RADIATIONS
RADIOISOTOPES
RADIOLOGY
THERAPY
YEARS LIVING RADIOISOTOPES
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