Genome-Enabled Advancement of Biomass to Biofuel Technology
Unlike Saccharomyces and even E. coli, the fundamental microbiology and biochemistry of Clostridium phytofermentans was largely unknown. The genus Clostridia is quite diverse and general methods to manipulate and characterize them often need to be developed. As anaerobes, they often don't behave the way more classically studied microbes will in fermentation processes. The results from these studies have allowed: 1) A fundamental understanding of the fermentation cycle in C. phytofermentans 2) Requirements to maximize ethanol yield in a fermentation process 3) An understanding of the critical growth and nutritional parameters required to ferment biomass to ethanol 4) Identification of key targets or genes to modify in order increase or improve any of the key traits of C. phytofermentans 5) The development of a genetic system to transform and manipulate the microbe Without these achievements, an industrially significant process for biomass fermentation to ethanol would not be economically possible. The development of a fermentation process with economic return on investment can be successfully developed with the technical learning achieved
- Research Organization:
- Qteros, Inc.
- Sponsoring Organization:
- USDOE Office of Science and Technology (EM-50)
- DOE Contract Number:
- FG02-07ER84930
- OSTI ID:
- 992418
- Report Number(s):
- DOE/ER84930-1
- Country of Publication:
- United States
- Language:
- English
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