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Title: Radiation delivery system and method

Patent ·
OSTI ID:874968
 [1];  [2];  [3]
  1. Overland Park, KS
  2. Los Alamos, NM
  3. Jemez Springs, NM
+ Show Author Affiliations

A radiation delivery system and method are described. The system includes a treatment configuration such as a stent, balloon catheter, wire, ribbon, or the like, a portion of which is covered with a gold layer. Chemisorbed to the gold layer is a radiation-emitting self-assembled monolayer or a radiation-emitting polymer. The radiation delivery system is compatible with medical catheter-based technologies to provide a therapeutic dose of radiation to a lesion following an angioplasty procedure.

Research Organization:
Los Alamos National Laboratory (LANL), Los Alamos, NM (United States)
DOE Contract Number:
W-7405-ENG-36
Assignee:
The Regents of the University of California (Los Alamos, NM)
Patent Number(s):
US 6500108
OSTI ID:
874968
Country of Publication:
United States
Language:
English

References (6)

Electrodeposition of radioactive rhenium onto stents to prevent restenosis journal May 1998
Recognition of Cations by Self-Assembled Monolayers of Crown Ethers journal August 1999
A Novel Organometallic Aqua Complex of Technetium for the Labeling of Biomolecules:  Synthesis of [ 99m Tc(OH 2 ) 3 (CO) 3 ] + from [ 99m TcO 4 ] - in Aqueous Solution and Its Reaction with a Bifunctional Ligand journal August 1998
Molecular-Level Control over Surface Order in Self-Assembled Monolayer Films of Thiols on Gold journal April 1988
Adsorption of bifunctional organic disulfides on gold surfaces journal June 1983
Selective Binding of Divalent Cations at the Surface of Self-Assembled Monolayers of an Aromatic Bifunctional Molecule Studied on a Quartz Crystal Microbalance journal February 1997

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Related Subjects

radiation
delivery
method
described
treatment
configuration
stent
balloon
catheter
wire
ribbon
portion
covered
gold
layer
chemisorbed
radiation-emitting
self-assembled
monolayer
polymer
compatible
medical
catheter-based
technologies
provide
therapeutic
dose
lesion
following
angioplasty
procedure
/600/424/