Method for detecting a pericentric inversion in a chromosome
Patent
·
OSTI ID:873343
- San Ramon, CA
A method is provided for determining a clastogenic signature of a sample of chromosomes by quantifying a frequency of a first type of chromosome aberration present in the sample; quantifying a frequency of a second, different type of chromosome aberration present in the sample; and comparing the frequency of the first type of chromosome aberration to the frequency of the second type of chromosome aberration. A method is also provided for using that clastogenic signature to identify a clastogenic agent or dosage to which the cells were exposed.
- Research Organization:
- Lawrence Livermore National Laboratory (LLNL), Livermore, CA (United States)
- DOE Contract Number:
- W-7405-ENG-48
- Assignee:
- Regents of University of California (Oakland, CA)
- Patent Number(s):
- US 6140057
- OSTI ID:
- 873343
- Country of Publication:
- United States
- Language:
- English
Similar Records
Method for obtaining chromosome painting probes
Rapid method for measuring clastogenic fingerprints using fluorescence in situ hybridization
Rapid method for measuring clastogenic fingerprints using fluorescence in situ hybridization
Patent
·
Sat Jan 01 00:00:00 EST 2000
·
OSTI ID:873343
Rapid method for measuring clastogenic fingerprints using fluorescence in situ hybridization
Patent
·
Tue Mar 28 00:00:00 EST 2000
·
OSTI ID:873343
Rapid method for measuring clastogenic fingerprints using fluorescence in situ hybridization
Patent
·
Sat Jan 01 00:00:00 EST 2000
·
OSTI ID:873343