skip to main content
OSTI.GOV title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: TGF-.beta. antagonists as mitigators of radiation-induced tissue damage

Patent ·
OSTI ID:870891
 [1]
  1. Oakland, CA
+ Show Author Affiliations

A method for treating tissue damage caused by radiation is described by use of a TGF-.beta. antagonist, such as an anti-TGF-.beta. antibody or a TGF-.beta. latency associated protein. It is administered not more than a week after exposure, and is particularly useful in mitigating the side effects of breast cancer therapy.

Research Organization:
Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States)
DOE Contract Number:
AC03-76SF00098
Assignee:
Regents of University of California (Oakland, CA)
Patent Number(s):
US 5616561
OSTI ID:
870891
Country of Publication:
United States
Language:
English

Similar Records

TGF-{beta} antagonists as mitigators of radiation-induced tissue damage
Patent · Tue Apr 01 00:00:00 EST 1997 · OSTI ID:870891
Antitransforming growth factor-{beta} antibody 1D11 ameliorates normal tissue damage caused by high-dose radiation
Journal Article · Sat Jul 01 00:00:00 EDT 2006 · International Journal of Radiation Oncology, Biology and Physics · OSTI ID:870891
+2 more
Transplantation of periaortic adipose tissue inhibits atherosclerosis in apoE −/− mice by evoking TGF-β1-mediated anti-inflammatory response in transplanted graft
Journal Article · Fri Jun 15 00:00:00 EDT 2018 · Biochemical and Biophysical Research Communications · OSTI ID:870891
+3 more

Related Subjects

tgf-
beta
antagonists
mitigators
radiation-induced
tissue
damage
method
treating
caused
radiation
described
antagonist
anti-tgf-
antibody
latency
associated
protein
administered
week
exposure
particularly
useful
mitigating
effects
breast
cancer
therapy
tissue damage
breast cancer
particularly useful
cancer therapy
damage caused
/514/