Kit for the rapid preparation of .sup.99m Tc red blood cells

Patent · Thu Jan 01 00:00:00 EST 1976

OSTI ID:862680

Richards, Powell ^[1]; Smith, Terry D ^[2]

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1. Bayport, NY
2. St. Ann, MO

A method and sample kit for the preparation of .sup.99m Tc-labeled red blood cells in a closed, sterile system. A partially evacuated tube, containing a freeze-dried stannous citrate formulation with heparin as an anticoagulant, allows whole blood to be automatically drawn from the patient. The radioisotope is added at the end of the labeling sequence to minimize operator exposure. Consistent 97% yields in 20 minutes are obtained with small blood samples. Freeze-dried kits have remained stable after five months.

• Research Organization: Brookhaven National Laboratory (BNL), Upton, NY (United States)
• DOE Contract Number: AT(30-1)-16
• Assignee: United States of America as represented by United States Energy (Washington, DC)
• Patent Number(s): US 3988429
• OSTI ID: 862680
• Country of Publication: United States
• Language: English

Related Subjects

kit
rapid
preparation
99m
tc
blood
cells
method
sample
tc-labeled
closed
sterile
partially
evacuated
tube
containing
freeze-dried
stannous
citrate
formulation
heparin
anticoagulant
allows
automatically
drawn
patient
radioisotope
added
labeling
sequence
minimize
operator
exposure
consistent
97
yields
20
minutes
obtained
samples
kits
remained
stable
five
months
blood sample
blood samples
blood cells
blood cell
partially evacuated
evacuated tube
/424/422/999/