TransRapid TR-07 maglev-spectrum magnetic field effects on daily pineal indoleamine metabolic rhythms in rodents

Conference · Fri Jan 01 00:00:00 EST 1993

OSTI ID:6282207

Groh, K R

This study examined the effects on pineal function of magnetic field (MF) exposures (ac and dc components) similar to those produced by the TransRapid TR-07 and other electromagnetic maglev systems (EMS). Rats were entrained to a light-dark cycle and then exposed to a continuous, or to an inverted, intermittent (on = 45 s, off = 15 s, induced current = 267 G/s) simulated multifrequency ac and dc magnetic field (MF) at 1 or 7 times the TR-07 maglev vehicle MF intensity for 2 hr. Other groups of rats were exposed to only the ac or the dc-component of the maglev MF. For comparison, one group was exposed to an inverted, intermittent 60-Hz MF. Each group was compared to an unexposed group of rats for changes in pineal melatonin and serotonin-N-acetyltransferase (NAT). MF exposures at an intensity equivalent to that produced by the TR-07 vehicle had no effect on melatonin or NAT compared with sham-exposed animals under any of the conditions examined. However, 7X TR-07-level continuous 2-h MF exposures significantly depressed pineal NAT by 45%. Pineal melatonin was also depressed 33--43% by a continuous 7X TR-07 MF exposure and 28% by an intermittent 60-Hz 850-mG MF, but the results were not statically significant. This study demonstrates that intermittent, combined ac and dc MFs similar to those produced by the TR-07 EMS maglev vehicle alter the normal circadian rhythm of pineal indoleamine metabolism. The pineal regulatory enzyme NAT was more sensitive to MF exposure than melatonin and may be a more desirable measure of the biological effects of MF exposure.

• Research Organization: Argonne National Lab., IL (United States)
• Sponsoring Organization: USDOE; USDOE, Washington, DC (United States)
• DOE Contract Number: W-31109-ENG-38
• OSTI ID: 6282207
• Report Number(s): ANL/BIM/CP-79650; CONF-930550-1; ON: DE93015143
• Resource Relation: Conference: 12. international conference on magnetically levitated systems and linear drives, Argonne, IL (United States), 19-21 May 1993
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
32 ENERGY CONSERVATION, CONSUMPTION, AND UTILIZATION
ELECTRIC FIELDS
BIOLOGICAL EFFECTS
LEVITATED TRAINS
HEALTH HAZARDS
MAGNETIC FIELDS
INDOLES
MELATONIN
PINEAL GLAND
RATS
SEROTONIN
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ANIMALS
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AUTONOMIC NERVOUS SYSTEM AGENTS
AZAARENES
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BODY
DRUGS
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HAZARDS
HETEROCYCLIC COMPOUNDS
HYDROXY COMPOUNDS
MAMMALS
NEUROREGULATORS
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
ORGANS
PYRROLES
RADIOPROTECTIVE SUBSTANCES
RODENTS
SYMPATHOMIMETICS
TRAINS
TRYPTAMINES
VEHICLES
VERTEBRATES
560400* - Other Environmental Pollutant Effects
320200 - Energy Conservation
Consumption
& Utilization- Transportation