Robotics for recombinant DNA and human genetics research

Conference · Mon Jan 01 00:00:00 EST 1990

OSTI ID:5894655

Beugelsdijk, T J

In October of 1989, molecular biologists throughout the world formally embarked on ultimately determining the set of genetic instructions for a human being. Called by some the Manhattan Project'' a molecular biology, pursuit of this goal is projected to require approximately 3000 man years of effort over a 15-year period. The Humane Genome Initiative is a worldwide research effort that has the goal of analyzing the structure of human deoxyribonucleic acid (DNA) and determining the location of all human genes. The Department of Energy (DOE) has designated three of its national laboratories as centers for the Human Genome Project. These are Los Alamos National Laboratory (LANL), Lawrence Livermore National Laboratory (LLNL), and Lawrence Berkeley Laboratory (LBL). These laboratories are currently working on different, but complementary technology development areas in support of the Human Genome Project. The robotics group at LANL is currently working at developing the technologies that address the problems associated with physical mapping. This article describes some of these problems and discusses some of the robotics approaches and engineering tolls applicable to their solution. 7 refs., 8 figs., 1 tab.

• Research Organization: Los Alamos National Laboratory (LANL), Los Alamos, NM (United States)
• Sponsoring Organization: USDOE; USDOE, Washington, DC (USA)
• DOE Contract Number: W-7405-ENG-36
• OSTI ID: 5894655
• Report Number(s): LA-UR-90-2884; CONF-910637-1; ON: DE90016440
• Resource Relation: Conference: 5. international conference on advanced robotics, Pisa (Italy), 20-22 Jun 1991
• Country of Publication: United States
• Language: English

Related Subjects

59 BASIC BIOLOGICAL SCIENCES
CHROMOSOMES
GENETIC MAPPING
GENETICS
RESEARCH PROGRAMS
MAN
MOLECULAR BIOLOGY
ROBOTS
AUTOMATION
DIAGNOSTIC USES
DNA HYBRIDIZATION
DNA SEQUENCING
HEREDITARY DISEASES
RECOMBINANT DNA
THERAPEUTIC USES
THERAPY
ANIMALS
BIOLOGY
DISEASES
DNA
HYBRIDIZATION
MAMMALS
MAPPING
NUCLEIC ACIDS
ORGANIC COMPOUNDS
PRIMATES
STRUCTURAL CHEMICAL ANALYSIS
USES
VERTEBRATES
550400* - Genetics
550200 - Biochemistry