Simulation studies of vapor bubble generation by short-pulse lasers
- and others
Formation of vapor bubbles is characteristic of many applications of short-pulse lasers in medicine. An understanding of the dynamics of vapor bubble generation is useful for developing and optimizing laser-based medical therapies. To this end, experiments in vapor bubble generation with laser light deposited in an aqueous dye solution near a fiber-optic tip have been performed. Numerical hydrodynamic simulations have been developed to understand and extrapolate results from these experiments. Comparison of two-dimensional simulations with the experiment shows excellent agreement in tracking the bubble evolution. Another regime of vapor bubble generation is short-pulse laser interactions with melanosomes. Strong shock generation and vapor bubble generation are common physical features of this interaction. A novel effect of discrete absorption by melanin granules within a melanosome is studied as a possible role in previously reported high Mach number shocks.
- Research Organization:
- Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)
- Sponsoring Organization:
- USDOE, Washington, DC (United States)
- DOE Contract Number:
- W-7405-ENG-48
- OSTI ID:
- 328500
- Report Number(s):
- UCRL-JC-126822; CONF-9709148-; ON: DE98051349
- Resource Relation:
- Conference: BiOS Europe `97, San Femo (Italy), 4-8 Sep 1997; Other Information: PBD: 26 Oct 1997
- Country of Publication:
- United States
- Language:
- English
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