Ferromagnetic particles as ultra-sensitive non-linear response labels for magnetic particles imaging (MPI) and sensing applications

Novosad, Valentine; Rozhkova, Elena A.; Nikitin, Maxim; Nikitin, Petr

Title: Ferromagnetic particles as ultra-sensitive non-linear response labels for magnetic particles imaging (MPI) and sensing applications

Patent · Tue Sep 12 00:00:00 EDT 2023

OSTI ID:2222327

Novosad, Valentine; Rozhkova, Elena A.; Nikitin, Maxim; Nikitin, Petr

A significant enhancement of detection capabilities of the room temperature MPQ is seen using optical lithography-defined, ferromagnetic iron-nickel alloy microdisks. Irreversible transitions between strongly non-collinear (vortex) and a collinear single domain states, driven by an ac magnetic field, translate into a nonlinear magnetic response that enables ultrasensitive detection of material at relatively small magnetic fields.

View Patent

Cite

Export

Save

Research Organization:: Argonne National Laboratory (ANL), Argonne, IL (United States)

Sponsoring Organization:: USDOE

DOE Contract Number:: AC02-06CH11357

Assignee:: UChicago Argonne, LLC (Chicago, IL)

Patent Number(s):: 11,754,648

Application Number:: 17/156,796

OSTI ID:: 2222327

Resource Relation:: Patent File Date: 01/25/2021

Country of Publication:: United States

Language:: English

References (55)

Stimuli-Responsive Magnetic Nanomicelles as Multifunctional Heat and Cargo Delivery Vehicles Kim, Dong-Hyun; Vitol, Elina A.; Liu, Jing Langmuir, Vol. 29, Issue 24 https://doi.org/10.1021/la3044158	journal	December 2012
Nanoscale Size Effect of Magnetic Nanocrystals and Their Utilization for Cancer Diagnosis via Magnetic Resonance Imaging Jun, Young-wook; Huh, Yong-Min; Choi, Jin-sil Journal of the American Chemical Society, Vol. 127, Issue 16 https://doi.org/10.1021/ja0422155	journal	April 2005
Micro-engineered local field control for high-sensitivity multispectral MRI Zabow, Gary; Dodd, Stephen; Moreland, John Nature, Vol. 453, Issue 7198 https://doi.org/10.1038/nature07048	journal	June 2008
Nanomagnetic actuation of receptor-mediated signal transduction Mannix, Robert J.; Kumar, Sanjay; Cassiola, Flávia Nature Nanotechnology, Vol. 3, Issue 1, p. 36-40 https://doi.org/10.1038/nnano.2007.418	journal	December 2007
Induction of Calcium Influx in Cortical Neural Networks by Nanomagnetic Forces Tay, Andy; Kunze, Anja; Murray, Coleman ACS Nano, Vol. 10, Issue 2 https://doi.org/10.1021/acsnano.5b07118	journal	January 2016
New type of biosensor based on magnetic nanoparticle detection Nikitin, Petr I.; Vetoshko, Petr M.; Ksenevich, Tatiana I. Journal of Magnetism and Magnetic Materials, Vol. 311, Issue 1 https://doi.org/10.1016/j.jmmm.2006.10.1180	journal	April 2007
Development of a remanence measurement-based SQUID system with in-depth resolution for nanoparticle imaging Ge, Song; Shi, Xiangyang; Baker, James R. Physics in Medicine and Biology, Vol. 54, Issue 10 https://doi.org/10.1088/0031-9155/54/10/N01	journal	April 2009
X-Space MPI: Magnetic Nanoparticles for Safe Medical Imaging Goodwill, Patrick William; Saritas, Emine Ulku; Croft, Laura Rose Advanced Materials, Vol. 24, Issue 28 https://doi.org/10.1002/adma.201200221	journal	March 2012
Temperature dependent magnetic properties of the GaAs substrate of spin-LEDs Ney, A.; Harris, J. S.; Parkin, S. S. P. Journal of Physics: Condensed Matter, Vol. 18, Issue 17 https://doi.org/10.1088/0953-8984/18/17/025	journal	April 2006
Remote control of cellular behaviour with magnetic nanoparticles Dobson, Jon Nature Nanotechnology, Vol. 3, Issue 3 https://doi.org/10.1038/nnano.2008.39	journal	March 2008
Nanomedicine-Challenge and Perspectives Riehemann, Kristina; Schneider, Stefan W.; Luger, Thomas A. Angewandte Chemie International Edition, Vol. 48, Issue 5 https://doi.org/10.1002/anie.200802585	journal	January 2009
Dynamic control of spin states in interacting magnetic elements Jain, Shikha; Novosad, Valentyn https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/8854871 US Patent Document 8,854,871	patent	October 2014
Protein-Functionalized Synthetic Antiferromagnetic Nanoparticles for Biomolecule Detection and Magnetic Manipulation Fu, Aihua; Hu, Wei; Xu, Liang Angewandte Chemie International Edition, Vol. 48, Issue 9 https://doi.org/10.1002/anie.200803994	journal	January 2009
Nucleation and annihilation of magnetic vortices in sub-micron permalloy dots Novosad, V.; Guslienko, K. Yu.; Shima, H. IEEE Transactions on Magnetics, Vol. 37, Issue 4 https://doi.org/10.1109/20.951062	journal	July 2001
Mechanoresponsive system based on sub-micron chitosan-functionalized ferromagnetic disks Kim, Dong-Hyun; Karavayev, Pavel; Rozhkova, Elena A. Journal of Materials Chemistry, Vol. 21, Issue 23 https://doi.org/10.1039/c1jm10272a	journal	January 2011
High-Moment Antiferromagnetic Nanoparticles with Tunable Magnetic Properties Hu, Wei; Wilson, Robert J.; Koh, AiLeen Advanced Materials, Vol. 20, Issue 8 https://doi.org/10.1002/adma.200703077	journal	April 2008
Biofunctionalized magnetic-vortex microdiscs for targeted cancer-cell destruction Kim, Dong-Hyun; Rozhkova, Elena A.; Ulasov, Ilya V. Nature Materials, Vol. 9, Issue 2 https://doi.org/10.1038/nmat2591	journal	November 2009
Ferromagnetic microdisks as carriers for biomedical applications Rozhkova, E. A.; Novosad, V.; Kim, D. -H. Journal of Applied Physics, Vol. 105, Issue 7 https://doi.org/10.1063/1.3061685	journal	April 2009
Rapid dry-reagent immunomagnetic biosensing platform based on volumetric detection of nanoparticles on 3D structures Orlov, Alexey V.; Bragina, Vera A.; Nikitin, Maxim P. Biosensors and Bioelectronics, Vol. 79 https://doi.org/10.1016/j.bios.2015.12.049	journal	May 2016
Three-dimensional real-time in vivo magnetic particle imaging Weizenecker, J.; Gleich, B.; Rahmer, J. Physics in Medicine and Biology, Vol. 54, Issue 5 https://doi.org/10.1088/0031-9155/54/5/L01	journal	February 2009
The fabrication of uniform cylindrical nanoshells and their use as spectrally tunable MRI contrast agents Zabow, G.; Dodd, S. J.; Moreland, J. Nanotechnology, Vol. 20, Issue 38 https://doi.org/10.1088/0957-4484/20/38/385301	journal	August 2009
Direct Observation of Internal Spin Structure of Magnetic Vortex Cores Wachowiak, A. Science, Vol. 298, Issue 5593 https://doi.org/10.1126/science.1075302	journal	October 2002
Shape-changing magnetic assemblies as high-sensitivity NMR-readable nanoprobes Zabow, G.; Dodd, S. J.; Koretsky, A. P. Nature, Vol. 520, Issue 7545 https://doi.org/10.1038/nature14294	journal	March 2015
Near-edge X-ray absorption fine-structure microscopy of organic and magnetic materials Ade, Harald; Stoll, Herman Nature Materials, Vol. 8, Issue 4 https://doi.org/10.1038/nmat2399	journal	April 2009
Tomographic imaging using the nonlinear response of magnetic particles Gleich, Bernhard; Weizenecker, Jürgen Nature, Vol. 435, Issue 7046 https://doi.org/10.1038/nature03808	journal	June 2005
Experimental results on fast 2D-encoded magnetic particle imaging Gleich, B.; Weizenecker, J.; Borgert, J. Physics in Medicine and Biology, Vol. 53, Issue 6 https://doi.org/10.1088/0031-9155/53/6/N01	journal	February 2008
Nanomagnetic detector array for biomolecular recognition Litvinov, Dmitri; Wilson, Richard https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/20100188075 US Patent Application 11/996945; 20100188075	patent-application	July 2010
Magnetic Immunoassays Nikitin, P. I.; Vetoshko, P. M.; Ksenevich, T. I. Sensor Letters, Vol. 5, Issue 1 https://doi.org/10.1166/sl.2007.007	journal	March 2007
Microfabricated magnetic structures for future medicine: from sensors to cell actuators Vitol, Elina A.; Novosad, Valentyn; Rozhkova, Elena A. Nanomedicine, Vol. 7, Issue 10 https://doi.org/10.2217/nnm.12.133	journal	October 2012
Design of Superparamagnetic Nanoparticles for Magnetic Particle Imaging (MPI) Du, Yimeng; Lai, Pui; Leung, Cheung International Journal of Molecular Sciences, Vol. 14, Issue 9 https://doi.org/10.3390/ijms140918682	journal	September 2013
Biocomputing based on particle disassembly Nikitin, Maxim P.; Shipunova, Victoria O.; Deyev, Sergey M. Nature Nanotechnology, Vol. 9, Issue 9 https://doi.org/10.1038/nnano.2014.156	journal	August 2014
Apparatus and method for influencing and/or detecting magnetic particles Gleich, Gernhard; Rahmer, Juergen Erwin https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/20130241548 US Patent Application 13/988862; 20130241548	patent-application	September 2013
A magnetic switch for the control of cell death signalling in in vitro and in vivo systems Cho, Mi Hyeon; Lee, Eun Jung; Son, Mina Nature Materials, Vol. 11, Issue 12 https://doi.org/10.1038/nmat3430	journal	October 2012
Microdevices containing photorecognizable coding patterns and methods of using and producing the same Wu, Lei; Wang, Xiaobo; Tao, Guoliang https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/20100260984 US Patent Application 12/760379; 20100260984	patent-application	October 2010
Nanoscale Materials for Tackling Brain Cancer: Recent Progress and Outlook Rozhkova, Elena A. Advanced Materials, Vol. 23, Issue 24 https://doi.org/10.1002/adma.201004714	journal	April 2011
Magnetic Vortex Core Observation in Circular Dots of Permalloy Shinjo, T. Science, Vol. 289, Issue 5481 https://doi.org/10.1126/science.289.5481.930	journal	August 2000
Micromagnetometry detection system and method for detecting magnetic signatures of magnetic materials Terki, Ferial; Bousseksou, Azzedine; Tran, Quang Hung https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/20150168507 US Patent Application 14/414430; 20150168507	patent-application	June 2015
Cardiac MPI of mice over the complete heart cycle Bontus, Claas; Rahmer, Jurgen; Gleich, Bernhard 2009 IEEE Nuclear Science Symposium Conference Record (NSS/MIC) https://doi.org/10.1109/NSSMIC.2009.5401930	conference	October 2009
Soliton-pair dynamics in patterned ferromagnetic ellipses Buchanan, Kristen S.; Roy, Pierre E.; Grimsditch, Marcos Nature Physics, Vol. 1, Issue 3 https://doi.org/10.1038/nphys173	journal	December 2005
Multifunctional Ferromagnetic Disks for Modulating Cell Function Vitol, Elina A.; Novosad, Valentyn; Rozhkova, Elena A. IEEE Transactions on Magnetics, Vol. 48, Issue 11 https://doi.org/10.1109/TMAG.2012.2198209	journal	November 2012
Advances in Giant Magnetoresistance Biosensors With Magnetic Nanoparticle Tags: Review and Outlook Wang, S. X. IEEE Transactions on Magnetics, Vol. 44, Issue 7 https://doi.org/10.1109/TMAG.2008.920962	journal	July 2008
Efficient Cisplatin Pro-Drug Delivery Visualized with Sub-100 nm Resolution: Interfacing Engineered Thermosensitive Magnetomicelles with a Living System Vitol, Elina A.; Rozhkova, Elena A.; Rose, Volker Advanced Materials Interfaces, Vol. 1, Issue 7 https://doi.org/10.1002/admi.201400182	journal	June 2014
Detection of fine magnetic particles coated on a thread using an HTS–SQUID Kawagishi, K.; Itozaki, H.; Kondo, T. Physica C: Superconductivity, Vol. 412-414 https://doi.org/10.1016/j.physc.2003.12.088	journal	October 2004
Highly sensitive room-temperature method of non-invasive in vivo detection of magnetic nanoparticles Nikitin, Maxim P.; Vetoshko, Petr M.; Brusentsov, Nikolai A. Journal of Magnetism and Magnetic Materials, Vol. 321, Issue 10 https://doi.org/10.1016/j.jmmm.2009.02.108	journal	May 2009
Quantitative real-time in vivo detection of magnetic nanoparticles by their nonlinear magnetization Nikitin, M. P.; Torno, M.; Chen, H. Journal of Applied Physics, Vol. 103, Issue 7 https://doi.org/10.1063/1.2830947	journal	April 2008
Applications of magnetic nanoparticles in biomedicine Pankhurst, Q. A.; Connolly, J.; Jones, S. K. Journal of Physics D: Applied Physics, Vol. 36, Issue 13 https://doi.org/10.1088/0022-3727/36/13/201	journal	June 2003
Progress in applications of magnetic nanoparticles in biomedicine Pankhurst, Q. A.; Thanh, N. T. K.; Jones, S. K. Journal of Physics D: Applied Physics, Vol. 42, Issue 22 https://doi.org/10.1088/0022-3727/42/22/224001	journal	November 2009
Magnetization reversal due to vortex nucleation, displacement, and annihilation in submicron ferromagnetic dot arrays Guslienko, K. Yu.; Novosad, V.; Otani, Y. Physical Review B, Vol. 65, Issue 2 https://doi.org/10.1103/PhysRevB.65.024414	journal	December 2001
Magnetic Immunoassay for Detection of Staphylococcal Toxins in Complex Media Orlov, Alexey V.; Khodakova, Julia A.; Nikitin, Maxim P. Analytical Chemistry, Vol. 85, Issue 2 https://doi.org/10.1021/ac303075b	journal	December 2012
Nucleic acid sample preparation Krishnan, Rajaram; Charlot, David J.; Tu, Eugene https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/20140356877 US Patent Application 14/311037; 20140356877	patent-application	December 2014
MPQ-cytometry: a magnetism-based method for quantification of nanoparticle–cell interactions Shipunova, V. O.; Nikitin, M. P.; Nikitin, P. I. Nanoscale, Vol. 8, Issue 25 https://doi.org/10.1039/C6NR03507H	journal	January 2016
Chemical Design of Nanoparticle Probes for High‐Performance Magnetic Resonance Imaging Jun, Young‐wook; Lee, Jae‐Hyun; Cheon, Jinwoo Angewandte Chemie International Edition, Vol. 47, Issue 28 https://doi.org/10.1002/anie.200701674	journal	June 2008
Method to determine the spatial distribution of magnetic particles and magnetic particle administering compositions Gleich, Bernhard; Weizenecker, Jurgen https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/20060248944 US Patent Application 10/552819; 20060248944	patent-application	November 2006
Biomedical Nanomagnetics: A Spin Through Possibilities in Imaging, Diagnostics, and Therapy Krishnan, Kannan M. IEEE Transactions on Magnetics, Vol. 46, Issue 7 https://doi.org/10.1109/TMAG.2010.2046907	journal	July 2010
Resonant magnetic disks for bioanalyte detection Park, Chang-Min https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/20090004758 US Patent Application 11/771833; 20090004758	patent-application	January 2009

Similar Records

Ferromagnetic particles as ultra-sensitive non-linear response labels for magnetic particles imaging (MPI) and sensing applications

Patent · Tue Jan 26 00:00:00 EST 2021 · OSTI ID:2222327

Novosad, Valentine; Rozhkova, Elena A.; Nikitin, Maxim; +1 more

Nonlinear oscillations of magnetization for ferromagnetic particles in the vortex state and their ordered arrays

Journal Article · Wed Jul 15 00:00:00 EDT 2009 · Journal of Experimental and Theoretical Physics · OSTI ID:2222327

Galkin, A Yu

Ferromagnetic microdisks as carriers for biomedical applications.

Journal Article · Thu Jan 01 00:00:00 EST 2009 · J. Appl. Phys. · OSTI ID:2222327

Rozhkova, E; Novosad, V; Kim, D -H; +4 more

Title: Ferromagnetic particles as ultra-sensitive non-linear response labels for magnetic particles imaging (MPI) and sensing applications

Citation Formats

References (55)

Similar Records

Related Subjects