Microfluidic systems, pumps, valves, fluidic chips thereof, and applications of same
Microfluidic systems, pumps, valves and applications of the same are provided. The microfluidic system may be a pump or a valve having a fluidic chip and an actuator controlling the opening and closing of the fluidic channel in the fluidic chip. The actuator may be disposed to tilt from the fluidic chip, forming a tilted-rotor peristaltic pump. Alternatively, the actuator may be a rolling ball actuator, and different fluidic chips may be used in different applications. For example, the fluidic chip may be a spiral pump chip having spiral channels, a rotary peristaltic pump chip having multiple output channels, or a multi-port valve chip having one port interconnected with multiple different ports. An analytical valve chip may switchably interconnect bioreactor and rinse/calibration input channels to sensor and waste output channels. The actuator of a random-access valve can move from one valve position to another without opening or closing intermediate ones.
- Research Organization:
- Los Alamos National Laboratory (LANL), Los Alamos, NM (United States); Vanderbilt Univ., Nashville, TN (United States)
- Sponsoring Organization:
- USDOE; National Institutes of Health (NIH); US Environmental Protection Agency (EPA); Defense Threat Reduction Agency (DTRA)
- DOE Contract Number:
- 468746; 20003; 5UG3TR002097-02; 83573601; CBMXCEL-XL1-2-001; HHSN44C; U01CA202229
- Assignee:
- Vanderbilt University (Nashville, TN)
- Patent Number(s):
- 11,745,180
- Application Number:
- 18/084,634
- OSTI ID:
- 2222266
- Resource Relation:
- Patent File Date: 12/20/2022
- Country of Publication:
- United States
- Language:
- English
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