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Title: Methods of producing cobalt nanoparticles and hollow gold nanospheres and kits for practicing same

Patent ·
OSTI ID:1986704

Provided are methods of producing cobalt nanoparticles (Co NPs). The methods include combining a cobalt salt, a capping agent, and a reducing agent, under Co NP synthesis conditions including a temperature selected to produce cobalt nanoparticles of a pre-selected diameter, where the temperature and pre-selected diameter are inversely related. In certain aspects, the methods further include producing hollow gold nano spheres (HGNs) using the cobalt nanoparticles as scaffolds. Also provided are cobalt nanoparticles and hollow gold nano spheres (HGNs) produced according to the present methods. Kits that find use in practicing the methods of the present disclosure are also provided.

Research Organization:
Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States)
Sponsoring Organization:
USDOE; National Aeronautics and Space Administration (NASA)
DOE Contract Number:
AC02-05CH11231; NNX15AQ01A
Assignee:
The Regents of the University of Califonia (Oakland, CA)
Patent Number(s):
11,471,940
Application Number:
16/465,708
OSTI ID:
1986704
Resource Relation:
Patent File Date: 12/01/2017
Country of Publication:
United States
Language:
English

References (13)

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Hollow Gold Nanospheres (Haunss) and Haunss-Loaded Microspheres Useful in Drug Delivery patent-application December 2011
Role of Temperature in the Growth of Silver Nanoparticles Through a Synergetic Reduction Approach journal September 2010
Synthesis, Characterization, and Tunable Optical Properties of Hollow Gold Nanospheres journal October 2006
Targeted Hollow Gold Nanostructures and Methods of Use patent-application October 2009
Particles and Methods for Long Wavelengths SERS patent-application March 2012
Targeted Hollow Gold Nanostructures and Methods of Use patent-application January 2014
Gold Hollow Nanospheres:  Tunable Surface Plasmon Resonance Controlled by Interior-Cavity Sizes journal April 2005
Metallic Nanoparticle Synthesis with Carbohydrate Capping Agent patent-application January 2014
Scaled-up production of plasmonic nanoparticles using microfluidics: from metal precursors to functionalized and sterilized nanoparticles journal January 2014
Novel Gold Nanostructures and Methods of Use patent-application February 2012
Targeted Photothermal Ablation of Murine Melanomas with Melanocyte-Stimulating Hormone Analog-Conjugated Hollow Gold Nanospheres journal February 2009

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