Topological supramolecular network enabled high-conductivity, stretchable organic bioelectronics

Jiang, Yuanwen; Zhang, Zhitao; Wang, Yi-Xuan; Li, Deling; Coen, Charles-Théophile; Hwaun, Ernie; Chen, Gan; Wu, Hung-Chin; Zhong, Donglai; Niu, Simiao; Wang, Weichen; Saberi, Aref; Lai, Jian-Cheng; Wu, Yilei; Wang, Yang; Trotsyuk, Artem A.; Loh, Kang Yong; Shih, Chien-Chung; Xu, Wenhui; Liang, Kui; Zhang, Kailiang; Bai, Yihong; Gurusankar, Gurupranav; Hu, Wenping; Jia, Wang; Cheng, Zhen; Dauskardt, Reinhold H.; Gurtner, Geoffrey C.; Tok, Jeffrey B.-H.; Deisseroth, Karl; Soltesz, Ivan; Bao, Zhenan

doi:10.1126/science.abj7564

Title: Topological supramolecular network enabled high-conductivity, stretchable organic bioelectronics

Journal Article · Fri Mar 25 00:00:00 EDT 2022 · Science

DOI:https://doi.org/10.1126/science.abj7564· OSTI ID:1866600

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Stanford Univ., CA (United States)
Stanford Univ., CA (United States); Tianjin Univ. (China)
Stanford Univ., CA (United States); Capital Medical Univ., Beijing (China)
Stanford Univ., CA (United States); Nanjing Univ. (China)
BOE Technology Group Co., Ltd., Beijing (China)
Tianjin Univ. (China)
Capital Medical University, Beijing (China)

Intrinsically stretchable bioelectronic devices based on soft and conducting organic materials have been regarded as the ideal interface for seamless and biocompatible integration with the human body. A remaining challenge is to combine high mechanical robustness with good electrical conduction, especially when patterned at small feature sizes. We develop a molecular engineering strategy based on a topological supramolecular network, which allows for the decoupling of competing effects from multiple molecular building blocks to meet complex requirements. We obtained simultaneously high conductivity and crack-onset strain in a physiological environment, with direct photopatternability down to the cellular scale. We further collected stable electromyography signals on soft and malleable octopus and performed localized neuromodulation down to single-nucleus precision for controlling organ-specific activities through the delicate brainstem.

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Research Organization:: SLAC National Accelerator Lab., Menlo Park, CA (United States)

Sponsoring Organization:: USDOE Office of Science (SC), Basic Energy Sciences (BES); BOE Technology Group Co., Ltd.; Stanford Wu Tsai Neurosciences Institute; National Natural Science Foundation of China (NSFC); China Scholarship Council

Grant/Contract Number:: AC02-76SF00515; 81971668; 201806255002

OSTI ID:: 1866600

Journal Information:: Science, Vol. 375, Issue 6587; ISSN 0036-8075

Publisher:: AAASCopyright Statement

Country of Publication:: United States

Language:: English

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