Kinetics and dose-response of residual 53BP1/γ-H2AX foci: Co-localization, relationship with DSB repair and clonogenic survival
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January 2007 |
Phase I Study of an Oral Histone Deacetylase Inhibitor, Suberoylanilide Hydroxamic Acid, in Patients With Advanced Cancer
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June 2005 |
Phase I and Pharmacokinetic Study of Vorinostat, A Histone Deacetylase Inhibitor, in Combination with Carboplatin and Paclitaxel for Advanced Solid Malignancies
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May 2007 |
Inhibition of homologous recombination with vorinostat synergistically enhances ganciclovir cytotoxicity
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December 2013 |
Structural Basis for the Methylation State-Specific Recognition of Histone H4-K20 by 53BP1 and Crb2 in DNA Repair
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December 2006 |
53BP1 is a reader of the DNA-damage-induced H2A Lys 15 ubiquitin mark
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June 2013 |
Differential Radiosensitivity Phenotypes of DNA-PKcs Mutations Affecting NHEJ and HRR Systems following Irradiation with Gamma-Rays or Very Low Fluences of Alpha Particles
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April 2014 |
Karyotypes of Human Lymphocytes Exposed to High-Energy Iron Ions
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November 2002 |
Clustered DNA damages induced in isolated DNA and in human cells by low doses of ionizing radiation
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January 2000 |
Relative Biological Effectiveness Variation Along Monoenergetic and Modulated Bragg Peaks of a 62-MeV Therapeutic Proton Beam: A Preclinical Assessment
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September 2014 |
Split-dose exposures versus dual ion exposure in human cell neoplastic transformation
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January 2007 |
Phase 1 study of the histone deacetylase inhibitor vorinostat (suberoylanilide hydroxamic acid [SAHA]) in patients with advanced leukemias and myelodysplastic syndromes
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February 2008 |
Histone deacetylase (HDAC) inhibitor activation of p21WAF1 involves changes in promoter-associated proteins, including HDAC1
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journal
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January 2004 |
The CGL1 (HeLa × Normal Skin Fibroblast) Human Hybrid Cell Line: A History of Ionizing Radiation Induced Effects on Neoplastic Transformation and Novel Future Directions in SNOLAB
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journal
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October 2017 |
Role of Homologous Recombination in the Alpha-Particle-Induced Bystander Effect for Sister Chromatid Exchanges and Chromosomal Aberrations
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August 2005 |
Issues for Simulation of Galactic Cosmic Ray Exposures for Radiobiological Research at Ground-Based Accelerators
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June 2015 |
High LET-Like Radiation Tracks at the Distal Side of Accelerated Proton Bragg Peak
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June 2021 |
Carbon Ion Therapy: A Modern Review of an Emerging Technology
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February 2020 |
Hallmarks of Cancer: The Next Generation
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March 2011 |
FDA Approval Summary: Vorinostat for Treatment of Advanced Primary Cutaneous T-Cell Lymphoma
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October 2007 |
Mapping the Relative Biological Effectiveness of Proton, Helium and Carbon Ions with High-Throughput Techniques
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journal
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December 2020 |
Differential Repair Protein Recruitment at Sites of Clustered and Isolated DNA Double-Strand Breaks Produced by High-Energy Heavy Ions
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journal
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January 2020 |
Efficient Rejoining of DNA Double-Strand Breaks despite Increased Cell-Killing Effectiveness following Spread-Out Bragg Peak Carbon-Ion Irradiation
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journal
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February 2016 |
DNA Double-stranded Breaks Induce Histone H2AX Phosphorylation on Serine 139
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journal
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March 1998 |
Valproic Acid Sensitizes Hepatocellular Carcinoma Cells to Proton Therapy by Suppressing NRF2 Activation
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journal
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November 2017 |
Induction of Anchorage-Independent Growth in Primary Human Cells Exposed to Protons or HZE Ions Separately or in Dual Exposures
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journal
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October 2005 |
Homologous Recombination Contributes to the Repair of DNA Double-Strand Breaks Induced by High-Energy Iron Ions
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journal
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January 2010 |
Complex exchanges are responsible for the increased effectiveness of C-ions compared to X-rays at the first post-irradiation mitosis
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journal
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August 2010 |
Repair Kinetics of DNA Double Strand Breaks Induced by Simulated Space Radiation
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journal
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December 2020 |
Histone Deacetylase Inhibitor Induced Radiation Sensitization Effects on Human Cancer Cells after Photon and Hadron Radiation Exposure
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journal
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February 2018 |
Recognition, signaling, and repair of DNA double-strand breaks produced by ionizing radiation in mammalian cells: The molecular choreography
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journal
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October 2012 |
Strategies to Enhance Radiosensitivity to Heavy Ion Radiation Therapy
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journal
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August 2018 |
Carbon Ion Radiotherapy: A Review of Clinical Experiences and Preclinical Research, with an Emphasis on DNA Damage/Repair
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journal
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June 2017 |
Human cell transformation in the study of sunlight-induced cancers in the skin of man
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journal
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June 1988 |
Second cancer risk after primary cancer treatment with three‐dimensional conformal, intensity‐modulated, or proton beam radiation therapy
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journal
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May 2020 |
A defect in DNA double strand break processing in cells from unaffected parents of retinoblastoma patients and other apparently normal humans
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journal
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June 2007 |
Proton-HZE-Particle Sequential Dual-Beam Exposures Increase Anchorage-Independent Growth Frequencies in Primary Human Fibroblasts
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journal
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September 2006 |
Development of vorinostat: Current applications and future perspectives for cancer therapy
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journal
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August 2009 |
Vorinostat, a histone deacetylase inhibitor, enhances the response of human tumor cells to ionizing radiation through prolongation of γ-H2AX foci
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journal
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August 2006 |
Enhancement of Radiation Sensitivity of Human Squamous Carcinoma Cells by Histone Deacetylase Inhibitors
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journal
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June 2004 |
Modulation of radiation response by histone deacetylase inhibition
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journal
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May 2005 |
Histone deacetylase inhibitor induces DNA damage, which normal but not transformed cells can repair
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journal
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August 2010 |
Spatiotemporal characterization of ionizing radiation induced DNA damage foci and their relation to chromatin organization
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journal
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April 2010 |
Response of Primary Human Fibroblasts Exposed to Solar Particle Event Protons
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journal
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August 2011 |
Biological Effectiveness of Accelerated Protons for Chromosome Exchanges
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journal
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October 2015 |
Novel function of HATs and HDACs in homologous recombination through acetylation of human RAD52 at double-strand break sites
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journal
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March 2018 |
Histone deacetylase inhibitors as radiosensitisers: effects on DNA damage signalling and repair
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journal
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January 2013 |
Endogenous DNA damage clusters in human skin, 3-D model, and cultured skin cells
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journal
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September 2005 |
Comparative Risk Predictions of Second Cancers After Carbon-Ion Therapy Versus Proton Therapy
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journal
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May 2016 |
Radiation Sensitivity of Primary Fibroblasts from Hereditary Retinoblastoma Family Members and Some Apparently Normal Controls: Colony Formation Ability during Continuous Low-Dose-Rate Gamma Irradiation
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journal
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May 2008 |
ATM and DNA-PK Function Redundantly to Phosphorylate H2AX after Exposure to Ionizing Radiation
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journal
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April 2004 |
Methylated lysine 79 of histone H3 targets 53BP1 to DNA double-strand breaks
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journal
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November 2004 |
P53 Binding Protein 1 (53bp1) Is an Early Participant in the Cellular Response to DNA Double-Strand Breaks
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journal
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December 2000 |
Physical basis of radiation protection in space travel
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journal
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November 2011 |
Biological Characterization of Low-Energy Ions with High-Energy Deposition on Human Cells
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journal
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August 2014 |
Combination Therapy With Histone Deacetylase Inhibitors (HDACi) for the Treatment of Cancer: Achieving the Full Therapeutic Potential of HDACi
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journal
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March 2018 |
Enhancement of Radiation Response in Osteosarcoma and Rhabomyosarcoma Cell Lines by Histone Deacetylase Inhibition
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journal
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September 2010 |
Radiosensitization of glioblastoma cells using a histone deacetylase inhibitor (SAHA) comparing carbon ions with X-rays
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journal
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June 2014 |
Modulation of cellular radiation responses by histone deacetylase inhibitors
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journal
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February 2006 |
Impact of Charged Particle Exposure on Homologous DNA Double-Strand Break Repair in Human Blood-Derived Cells
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journal
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November 2015 |
RNF168 ubiquitylates 53BP1 and controls its response to DNA double-strand breaks
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journal
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December 2013 |
Advantages and Limitations in the Use of Combination Therapies with Charged Particle Radiation Therapy
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journal
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August 2018 |
Tumor Microenvironment as a Regulator of Radiation Therapy: New Insights into Stromal-Mediated Radioresistance
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journal
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October 2020 |
Inter-individual variation in DNA double-strand break repair in human fibroblasts before and after exposure to low doses of ionizing radiation
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journal
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January 2010 |
In vitro characterization of cells derived from chordoma cell line U-CH1 following treatment with X-rays, heavy ions and chemotherapeutic drugs
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journal
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September 2011 |
Induction and Repair of DNA DSB as Revealed by H2AX Phosphorylation Foci in Human Fibroblasts Exposed to Low- and High-LET Radiation: Relationship with Early and Delayed Reproductive Cell Death
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journal
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April 2015 |
Relative biological effectiveness (RBE), quality factor ( Q ), and radiation weighting factor ( w R ): ICRP Publication 92: Approved by the Commission in January 2003
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journal
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October 2003 |
Combination of suberoylanilide hydroxamic acid with heavy ion therapy shows promising effects in infantile sarcoma cell lines
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journal
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September 2011 |
Solar particle event storm shelter requirements for missions beyond low Earth orbit
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journal
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May 2018 |