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Title: Modifying flowering time in maize

Patent ·
OSTI ID:1771705

The present invention provides compositions and methods for modulating the reproductive transition in plants, such as grasses (e.g., maize). In particular, the invention provides methods for enhancing agronomic properties in plants by modulating expression of GRMZM2G171650 (zmm22) or homologs thereof. Modulation of expression of one or more additional genes which affect reproductive transition such as zagl1, in conjunction with such modulation of expression is also contemplated. Nucleic acid constructs for down-regulation of GRMZM2G171650 are also contemplated, as are transgenic plants, and products produced therefrom, that demonstrate altered development such as extended flowering time and display associated phenotypes such as enhanced yield of vegetative biomass, improved digestibility, and increased disease resistance. Plants described herein may be used, for example, as improved forage or feed crops or in biofuel production.

Research Organization:
Univ. of Wisconsin, Madison, WI (United States)
Sponsoring Organization:
USDOE
DOE Contract Number:
FC02-07ER64494
Assignee:
Wisconsin Alumni Research Foundation (Madison, WI)
Patent Number(s):
10,858,664
Application Number:
14/296,352
OSTI ID:
1771705
Resource Relation:
Patent File Date: 06/04/2014
Country of Publication:
United States
Language:
English

References (17)

Maize Microrna Sequences and Targets Thereof for Agronomic Traits patent-application January 2016
Role of MADS box proteins and their cofactors in combinatorial control of gene expression and cell development journal October 2003
The Genetic Architecture of Flowering Time and Photoperiod Sensitivity in Maize as Revealed by QTL Review and Meta Analysis journal June 2012
TaVRT-2 , a Member of the St MADS-11 Clade of Flowering Repressors, Is Regulated by Vernalization and Photoperiod in Wheat journal July 2005
PnMADS1 , encoding an StMADS11-clade protein, acts as a repressor of flowering in Pharbitis nil journal August 2008
The study of two barley Type I-like MADS-boxgenes as potential targets of epigenetic regulation during seed development journal September 2012
Conserved noncoding genomic sequences associated with a flowering-time quantitative trait locus in maize journal June 2007
Genetic Architecture of Flowering Time in Maize As Inferred From Quantitative Trait Loci Meta-analysis and Synteny Conservation With the Rice Genome journal December 2004
PICARA, an Analytical Pipeline Providing Probabilistic Inference about A Priori Candidates Genes Underlying Genome-Wide Association QTL in Plants journal November 2012
The control of developmental phase transitions in plants journal September 2011
ODDSOC2 Is a MADS Box Floral Repressor That Is Down-Regulated by Vernalization in Temperate Cereals     journal April 2010
OsMADS22, an STMADS11-like MADS-box gene of rice, is expressed in non-vegetative tissues and its ectopic expression induces spikelet meristem indeterminacy journal January 2005
Flowering time control and applications in plant breeding journal October 2009
Nucleic acid molecules and other molecules associated with transcription in plants and uses thereof for plant improvement patent-application August 2007
MADS-box genes of maize: frequent targets of selection during domestication journal December 2010
The major clades of MADS-box genes and their role in the development and evolution of flowering plants journal December 2003
The Genetic Architecture of Maize Flowering Time journal August 2009

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