Producing adipic acid and related compounds using hybrid polyketide synthases

Hagen, Andrew R.; Poust, Sean; Katz, Leonard; Keasling, Jay D.

Title: Producing adipic acid and related compounds using hybrid polyketide synthases

Patent · Tue Sep 01 00:00:00 EDT 2020

OSTI ID:1735202

Hagen, Andrew R.; Poust, Sean; Katz, Leonard; Keasling, Jay D.

The present invention provides for a polyketide synthase (PKS) capable of synthesizing a carboxylic acid, said PKS comprising a synthetic or hybrid module. The present invention also provides for a host cell comprising the PKS and when cultured produces the carboxylic acid. In some embodiments, the carboxylic acid is adipic acid.

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Research Organization:: Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States)

Sponsoring Organization:: USDOE

DOE Contract Number:: AC02-05CH11231

Assignee:: The Regents of the University of California (Oakland, CA)

Patent Number(s):: 10,760,069

Application Number:: 15/867,575

OSTI ID:: 1735202

Resource Relation:: Patent File Date: 01/10/2018

Country of Publication:: United States

Language:: English

References (33)

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