Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways
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August 2012 |
An Abundance of Rare Functional Variants in 202 Drug Target Genes Sequenced in 14,002 People
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May 2012 |
Recent Explosive Human Population Growth Has Resulted in an Excess of Rare Genetic Variants
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May 2012 |
Evolution and Functional Impact of Rare Coding Variation from Deep Sequencing of Human Exomes
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May 2012 |
Analysis of 6,515 exomes reveals the recent origin of most human protein-coding variants
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November 2012 |
Whole-genome sequence???based analysis of high-density lipoprotein cholesterol
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January 2013 |
Association of Low-Frequency and Rare Coding-Sequence Variants with Blood Lipids and Coronary Heart Disease in 56,000 Whites and Blacks
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February 2014 |
Exome array analysis identifies new loci and low-frequency variants influencing insulin processing and secretion
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December 2012 |
Loss-of-function mutations in SLC30A8 protect against type 2 diabetes
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March 2014 |
Searching for missing heritability: Designing rare variant association studies
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January 2014 |
Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium: Design of Prospective Meta-Analyses of Genome-Wide Association Studies From 5 Cohorts
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February 2009 |
Best Practices and Joint Calling of the HumanExome BeadChip: The CHARGE Consortium
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July 2013 |
An integrated encyclopedia of DNA elements in the human genome
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September 2012 |
ENCODE Data in the UCSC Genome Browser: year 5 update
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November 2012 |
The incretin system: glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors in type 2 diabetes
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November 2006 |
Insulin Secretion in Response to Glycemic Stimulus: Relation of Delayed Initial Release to Carbohydrate intolerance in Mild Diabetes Mellitus*
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March 1967 |
Glucagon-like peptide 1 and appetite
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February 2013 |
Safety, tolerability and sustained weight loss over 2 years with the once-daily human GLP-1 analog, liraglutide
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August 2011 |
Predicted structure of agonist-bound glucagon-like peptide 1 receptor, a class B G protein-coupled receptor
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November 2012 |
Polymorphism and recombination events at the ABO locus: a major challenge for genomic ABO blood grouping strategies
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August 2001 |
Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease
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March 2011 |
Biological, clinical and population relevance of 95 loci for blood lipids
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August 2010 |
Mouse Glucose Transporter 9 Splice Variants Are Expressed in Adult Liver and Kidney and Are Up-Regulated in Diabetes
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March 2006 |
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk
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January 2010 |
Re-sequencing Expands Our Understanding of the Phenotypic Impact of Variants at GWAS Loci
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January 2014 |
Multiple functional polymorphisms in the G6PC2 gene contribute to the association with higher fasting plasma glucose levels
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March 2013 |
dbNSFP v2.0: A Database of Human Non-synonymous SNVs and Their Functional Predictions and Annotations
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July 2013 |
A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance
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May 2012 |
Human growth factor receptor bound 14 binds the activated insulin receptor and alters the insulin-stimulated tyrosine phosphorylation levels of multiple proteins
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January 2001 |
Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes
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August 2012 |
A Common Functional Regulatory Variant at a Type 2 Diabetes Locus Upregulates ARAP1 Expression in the Pancreatic Beta Cell
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February 2014 |
Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis
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June 2010 |
Common Missense Variant in the Glucokinase Regulatory Protein Gene Is Associated With Increased Plasma Triglyceride and C-Reactive Protein but Lower Fasting Glucose Concentrations
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August 2008 |
Cellular characterisation of the GCKR P446L variant associated with type 2 diabetes risk
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October 2011 |
The P446L variant in GCKR associated with fasting plasma glucose and triglyceride levels exerts its effect through increased glucokinase activity in liver
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July 2009 |
Pharmacological Characterization of Human Incretin Receptor Missense Variants
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October 2009 |
Polymorphism and Ligand Dependent Changes in Human Glucagon-Like Peptide-1 Receptor (GLP-1R) Function: Allosteric Rescue of Loss of Function Mutation
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May 2011 |
Glucose intolerance but normal satiety in mice with a null mutation in the glucagon–like peptide 1 receptor gene
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Genetics and phenomics of inherited and sporadic non-autoimmune hyperthyroidism
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G protein-coupled receptors: mutations and endocrine diseases
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zCall: a rare variant caller for array-based genotyping
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July 2012 |
Fast and accurate short read alignment with Burrows-Wheeler transform
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May 2009 |
The Sequence Alignment/Map format and SAMtools
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June 2009 |
NARWHAL, a primary analysis pipeline for NGS data
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November 2011 |
SOAP: short oligonucleotide alignment program
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January 2008 |
A framework for variation discovery and genotyping using next-generation DNA sequencing data
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April 2011 |
An integrative variant analysis suite for whole exome next-generation sequencing data
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January 2012 |
The variant call format and VCFtools
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June 2011 |
SNP detection for massively parallel whole-genome resequencing
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May 2009 |
Whole-Exome Sequencing Identifies Rare and Low-Frequency Coding Variants Associated with LDL Cholesterol
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February 2014 |
Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge
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Analysis of serial measurements in medical research.
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Association between birth weight and visceral fat in adults
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June 2010 |
Incidence of Type 2 diabetes in England and its association with baseline impaired fasting glucose: The Ely study 1990-2000
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The EGIR-RISC STUDY (The European group for the study of insulin resistance: relationship between insulin sensitivity and cardiovascular disease risk): I. Methodology and Objectives
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March 2004 |
Systematic evaluation of coding variation identifies a candidate causal variant in TM6SF2 influencing total cholesterol and myocardial infarction risk
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March 2014 |
Testing Association of Statistically Inferred Haplotypes with Discrete and Continuous Traits in Samples of Unrelated Individuals
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January 2002 |
The Synthesis of Regression Slopes in Meta-Analysis
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August 2007 |
Common Inherited Variation in Mitochondrial Genes Is Not Enriched for Associations with Type 2 Diabetes or Related Glycemic Traits
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August 2010 |
CHARMM: The biomolecular simulation program
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July 2009 |
Scalable molecular dynamics with NAMD
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Ancestry deconvolution and partial polygenic score can improve susceptibility predictions in recently admixed individuals
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April 2020 |
Exome array analysis identifies new loci and low-frequency variants influencing insulin processing and secretion
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text
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January 2013 |
An Abundance of Rare Functional Variants in 202 Drug Target Genes Sequenced in 14,002 People
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text
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January 2012 |
A Common Functional Regulatory Variant at a Type 2 Diabetes Locus Upregulates ARAP1 Expression in the Pancreatic Beta Cell
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text
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January 2014 |
Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways
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text
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January 2012 |
Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes
- Libraries, The University of North Carolina at Chapel Hill University
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The University of North Carolina at Chapel Hill University Libraries
https://doi.org/10.17615/sa0w-h884
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text
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January 2012 |
An integrated encyclopedia of DNA elements in the human genome
- Libraries, The University of North Carolina at Chapel Hill University
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The University of North Carolina at Chapel Hill University Libraries
https://doi.org/10.17615/wcvb-k036
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text
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January 2012 |
CHARMM: the biomolecular simulation program
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January 2009 |
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk
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text
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January 2010 |
Erratum: New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk
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May 2010 |
Large-Scale Association Analysis Identifies 13 New Susceptibility Loci for Coronary Artery Disease
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June 2011 |
The Synthesis of Regression Slopes in Meta-Analysis
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Somatic and germline mutations of the TSH receptor gene in thyroid diseases
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Functional characteristics of three new germline mutations of the thyrotropin receptor gene causing autosomal dominant toxic thyroid hyperplasia.
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Whole Genome Sequence-Based Analysis of a Model Complex Trait, High Density Lipoprotein Cholesterol
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Incretin Therapy – Present and Future
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