Analysis of Residual Explosives by Swab Touch Spray Ionization Mass Spectrometry

Bain, Ryan M.; Fedick, Patrick W.; Dilger, Jonathan M.; Cooks, R. Graham

doi:10.1002/prep.201800122

Title: Analysis of Residual Explosives by Swab Touch Spray Ionization Mass Spectrometry

Journal Article · Wed Sep 26 00:00:00 EDT 2018 · Propellants, Explosives, Pyrotechnics

DOI:https://doi.org/10.1002/prep.201800122· OSTI ID:1609707

Bain, Ryan M. ^[1]; Fedick, Patrick W. ^[1]; Dilger, Jonathan M. ^[2]; Cooks, R. Graham ^[1]

Purdue Univ., West Lafayette, IN (United States)
Naval Surface Warfare Center Crane Division, Crane, IN (United States)

Abstract Swab touch spray ionization mass spectrometry, an ambient ionization technique, has been applied to the analysis of six explosives from various surfaces including glass, metal, Teflon, plastic, human hands and three types of gloves (nitrile, vinyl and latex). A swab, attached to a metallic handle, was used to sample explosive residues and acted as the ion source. The explosives, 1,3,5‐trinitro‐1,3,5‐triazinane (RDX), 1,3,5,7‐tetranitro‐1,3,5,7‐tetrazocane (HMX), and 2,2‐bis[(nitrooxy)methyl]propane‐1,3‐diyl dinitrate (PETN) had an absolute limit of detection of 10 ng from all the surfaces except for PETN from the nitrile gloves (limit of detection 100 ng). Sodium perchlorate, 2‐methyl‐1,3,5‐trinitrobenzene (TNT) and tetra‐butylammonium perchlorate had limits of detection of 100 pg, 10 pg, and 1 pg, respectively from all surfaces. This study demonstrates the feasibility of swab touch spray ionization mass spectrometry for detection of a wide array of explosives from a variety of forensically applicable surfaces with disposable, commercial, tamperproof and individually‐wrapped conductive swabs without complicated/lengthy sample preparations or extractions.

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Research Organization:: Purdue Univ., West Lafayette, IN (United States)

Sponsoring Organization:: USDOE Office of Science (SC), Basic Energy Sciences (BES)

Grant/Contract Number:: FG02-06ER15807

OSTI ID:: 1609707

Alternate ID(s):: OSTI ID: 1473990

Journal Information:: Propellants, Explosives, Pyrotechnics, Vol. 43, Issue 11; ISSN 0721-3115

Publisher:: WileyCopyright Statement

Country of Publication:: United States

Language:: English

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Cited by: 18 works

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References (44)

Low-Temperature Plasma Probe for Ambient Desorption Ionization Harper, Jason D.; Charipar, Nicholas A.; Mulligan, Christopher C. Analytical Chemistry, Vol. 80, Issue 23 https://doi.org/10.1021/ac801641a	journal	December 2008
Paper Spray for Direct Analysis of Complex Mixtures Using Mass Spectrometry Wang, He; Liu, Jiangjiang; Cooks, R. Graham Angewandte Chemie International Edition, Vol. 49, Issue 5 https://doi.org/10.1002/anie.200906314	journal	January 2010
Fabric analysis by ambient mass spectrometry for explosives and drugs Talaty, Nari; Mulligan, Christopher C.; Justes, Dina R. The Analyst, Vol. 133, Issue 11 https://doi.org/10.1039/b807934j	journal	January 2008
Trace detection of inorganic oxidants using desorption electrospray ionization (DESI) mass spectrometry Sokol, Ewa; Jackson, Ayanna; Cooks, R. Open Chemistry, Vol. 9, Issue 5 https://doi.org/10.2478/s11532-011-0065-z	journal	October 2011
Direct detection of explosives on solid surfaces by low temperature plasma desorption mass spectrometry Zhang, Yan; Ma, Xiaoxiao; Zhang, Sichun The Analyst, Vol. 134, Issue 1 https://doi.org/10.1039/B816230A	journal	January 2009
Direct ion generation from swabs Jarmusch, Alan K.; Pirro, Valentina; Logsdon, David L. Talanta, Vol. 184 https://doi.org/10.1016/j.talanta.2018.02.105	journal	July 2018
Latent Fingerprint Chemical Imaging by Mass Spectrometry Ifa, D. R.; Manicke, N. E.; Dill, A. L. Science, Vol. 321, Issue 5890 https://doi.org/10.1126/science.1157199	journal	August 2008
A review of X-ray explosives detection techniques for checked baggage Wells, K.; Bradley, D. A. Applied Radiation and Isotopes, Vol. 70, Issue 8 https://doi.org/10.1016/j.apradiso.2012.01.011	journal	August 2012
Screening for trace explosives by AccuTOF™-DART®: An in-depth validation study Sisco, Edward; Dake, Jeffrey; Bridge, Candice Forensic Science International, Vol. 232, Issue 1-3 https://doi.org/10.1016/j.forsciint.2013.07.006	journal	October 2013
Swab touch spray mass spectrometry for rapid analysis of organic gunshot residue from human hand and various surfaces using commercial and fieldable mass spectrometry systems Fedick, Patrick W.; Bain, Ryan M. Forensic Chemistry, Vol. 5 https://doi.org/10.1016/j.forc.2017.06.005	journal	September 2017
Portable Raman explosives detection Moore, David S.; Scharff, R. Jason Analytical and Bioanalytical Chemistry, Vol. 393, Issue 6-7 https://doi.org/10.1007/s00216-008-2499-5	journal	November 2008
A critical review of ion mobility spectrometry for the detection of explosives and explosive related compounds Ewing, R. Talanta, Vol. 54, Issue 3 https://doi.org/10.1016/S0039-9140(00)00565-8	journal	May 2001
Desorption Electrospray Ionization of Explosives on Surfaces: Sensitivity and Selectivity Enhancement by Reactive Desorption Electrospray Ionization Cotte-Rodríguez, Ismael; Takáts, Zoltán; Talaty, Nari Analytical Chemistry, Vol. 77, Issue 21 https://doi.org/10.1021/ac050995+	journal	September 2005
Autonomous in Situ Analysis and Real-Time Chemical Detection Using a Backpack Miniature Mass Spectrometer: Concept, Instrumentation Development, and Performance Hendricks, Paul I.; Dalgleish, Jon K.; Shelley, Jacob T. Analytical Chemistry, Vol. 86, Issue 6 https://doi.org/10.1021/ac403765x	journal	February 2014
Application of Single Drop Microextraction for Analysis of Chemical Warfare Agents and Related Compounds in Water by Gas Chromatography/Mass Spectrometry Palit, Meehir; Pardasani, Deepak; Gupta, A. K. Analytical Chemistry, Vol. 77, Issue 2 https://doi.org/10.1021/ac0486948	journal	January 2005
Forensic Chemistry and Ambient Mass Spectrometry: A Perfect Couple Destined for a Happy Marriage? Correa, Deleon N.; Santos, Jandyson M.; Eberlin, Livia S. Analytical Chemistry, Vol. 88, Issue 5 https://doi.org/10.1021/acs.analchem.5b02397	journal	February 2016
A Low-Cost, Simplified Platform of Interchangeable, Ambient Ionization Sources for Rapid, Forensic Evidence Screening on Portable Mass Spectrometric Instrumentation Fedick, Patrick; Fatigante, William; Lawton, Zachary Instruments, Vol. 2, Issue 2 https://doi.org/10.3390/instruments2020005	journal	March 2018
Precursor and Neutral Loss Scans in an RF Scanning Linear Quadrupole Ion Trap Snyder, Dalton T.; Szalwinski, Lucas J.; Schrader, Robert L. Journal of The American Society for Mass Spectrometry, Vol. 29, Issue 7 https://doi.org/10.1007/s13361-018-1920-3	journal	March 2018
Direct, trace level detection of explosives on ambient surfaces by desorption electrospray ionization mass spectrometry Takáts, Zoltán; Cotte-Rodriguez, Ismael; Talaty, Nari Chem. Commun., Issue 15 https://doi.org/10.1039/B418697D	journal	January 2005
Spray mechanism in paper spray ionization Espy, Ryan D.; Muliadi, Ariel R.; Ouyang, Zheng International Journal of Mass Spectrometry, Vol. 325-327 https://doi.org/10.1016/j.ijms.2012.06.017	journal	July 2012
Detection of Explosives and Related Compounds by Low-Temperature Plasma Ambient Ionization Mass Spectrometry Garcia-Reyes, Juan F.; Harper, Jason D.; Salazar, Gary A. Analytical Chemistry, Vol. 83, Issue 3 https://doi.org/10.1021/ac1029117	journal	February 2011
Development and validation of highly selective screening and confirmatory methods for the qualitative forensic analysis of organic explosive compounds with high performance liquid chromatography coupled with (photodiode array and) LTQ ion trap/Orbitrap mass spectrometric detections (HPLC-(PDA)-LTQOrbitrap) Xu, Xiaoma; Koeberg, Mattijs; Kuijpers, Chris-Jan Science & Justice, Vol. 54, Issue 1 https://doi.org/10.1016/j.scijus.2013.08.003	journal	January 2014
Ion chromatography-mass spectrometry: A review of recent technologies and applications in forensic and environmental explosives analysis Barron, Leon; Gilchrist, Elizabeth Analytica Chimica Acta, Vol. 806 https://doi.org/10.1016/j.aca.2013.10.047	journal	January 2014
Direct drug analysis from oral fluid using medical swab touch spray mass spectrometry Pirro, Valentina; Jarmusch, Alan K.; Vincenti, Marco Analytica Chimica Acta, Vol. 861 https://doi.org/10.1016/j.aca.2015.01.008	journal	February 2015
Detection of nitro-organic and peroxide explosives in latent fingermarks by DART- and SALDI-TOF-mass spectrometry Rowell, Frederick; Seviour, John; Lim, Angelina Yimei Forensic Science International, Vol. 221, Issue 1-3 https://doi.org/10.1016/j.forsciint.2012.04.007	journal	September 2012
Non-proximate detection of explosives and chemical warfare agent simulants by desorption electrospray ionization mass spectrometry Cotte-Rodríguez, Ismael; Cooks, R. Graham Chem. Commun., Issue 28, p. 2968-2970 https://doi.org/10.1039/B606020J	journal	June 2006
Development of a plug-type IMS-MS instrument and its applications in resolving problems existing in in-situ detection of illicit drugs and explosives by IMS Du, Zhenxia; Sun, Tangqiang; Zhao, Jianan Talanta, Vol. 184 https://doi.org/10.1016/j.talanta.2018.02.086	journal	July 2018
Detection of Explosives as Negative Ions Directly from Surfaces Using a Miniature Mass Spectrometer Sanders, Nathaniel L.; Kothari, Sameer; Huang, Guangming Analytical Chemistry, Vol. 82, Issue 12 https://doi.org/10.1021/ac1008157	journal	June 2010
Non-contact halogen lamp heating assisted LTP ionization miniature rectilinear ion trap: a platform for rapid, on-site explosives analysis Chen, Wendong; Hou, Keyong; Xiong, Xingchuang The Analyst, Vol. 138, Issue 17 https://doi.org/10.1039/c3an00555k	journal	January 2013
Application of paper spray ionization for explosives analysis Tsai, Chia-Wei; Tipple, Christopher A.; Yost, Richard A. Rapid Communications in Mass Spectrometry, Vol. 31, Issue 19 https://doi.org/10.1002/rcm.7932	journal	September 2017
Novel Selectivity-Based Forensic Toxicological Validation of a Paper Spray Mass Spectrometry Method for the Quantitative Determination of Eight Amphetamines in Whole Blood Teunissen, Sebastiaan F.; Fedick, Patrick W.; Berendsen, Bjorn J. A. Journal of The American Society for Mass Spectrometry, Vol. 28, Issue 12 https://doi.org/10.1007/s13361-017-1790-0	journal	September 2017
Corrigendum to “Monitoring of mutagenic process with piezoelectric quartz crystal impedance analysis” [Talanta 53 (2000) 525–533] Zhang, J. Talanta, Vol. 54, Issue 5 https://doi.org/10.1016/S0039-9140(01)00345-9	journal	June 2001
Analysis of explosives using corona discharge ionization combined with ion mobility spectrometry–mass spectrometry Lee, Jihyeon; Park, Sehwan; Cho, Soo Gyeong Talanta, Vol. 120 https://doi.org/10.1016/j.talanta.2013.11.059	journal	March 2014
Analysis of Gunshot Residue and Associated Materials-A Review: ANALYSIS OF GUNSHOT RESIDUE AND ASSOCIATED MATERIALS Dalby, Oliver; Butler, David; Birkett, Jason W. Journal of Forensic Sciences, Vol. 55, Issue 4 https://doi.org/10.1111/j.1556-4029.2010.01370.x	journal	April 2010
Detection of explosives on skin using ambient ionization mass spectrometry Justes, Dina R.; Talaty, Nari; Cotte-Rodriguez, Ismael Chemical Communications, Issue 21 https://doi.org/10.1039/b703655h	journal	January 2007
Analytical Validation of a Portable Mass Spectrometer Featuring Interchangeable, Ambient Ionization Sources for High Throughput Forensic Evidence Screening Lawton, Zachary E.; Traub, Angelica; Fatigante, William L. Journal of The American Society for Mass Spectrometry, Vol. 28, Issue 6 https://doi.org/10.1007/s13361-016-1562-2	journal	December 2016
Instrumentation for trace detection of high explosives Moore, D. S. Review of Scientific Instruments, Vol. 75, Issue 8 https://doi.org/10.1063/1.1771493	journal	August 2004
Versatile New Ion Source for the Analysis of Materials in Open Air under Ambient Conditions Cody, Robert B.; Laramée, James A.; Durst, H. Dupont Analytical Chemistry, Vol. 77, Issue 8, p. 2297-2302 https://doi.org/10.1021/ac050162j	journal	April 2005
Gas chromatography positive chemical ionization and tandem mass spectrometry for the analysis of organic high explosives Perr, J.; Furton, K.; Almirall, J. Talanta, Vol. 67, Issue 2 https://doi.org/10.1016/j.talanta.2005.01.035	journal	August 2005
Explosives Detection Using Direct Analysis in Real Time (DART) Mass Spectrometry Nilles, J. Michael; Connell, Theresa R.; Stokes, Sarah T. Propellants, Explosives, Pyrotechnics, Vol. 35, Issue 5 https://doi.org/10.1002/prep.200900084	journal	June 2010
Mass Spectrometry Sampling Under Ambient Conditions with Desorption Electrospray Ionization Takats, Z. Science, Vol. 306, Issue 5695, p. 471-473 https://doi.org/10.1126/science.1104404	journal	October 2004
In Situ Explosive Detection Using a Miniature Plasma Ion Source and a Portable Mass Spectrometer Dalgleish, Jon K.; Hou, Keyong; Ouyang, Zheng Analytical Letters, Vol. 45, Issue 11 https://doi.org/10.1080/00032719.2012.675485	journal	July 2012
Recent advances in ambient mass spectrometry of trace explosives Forbes, Thomas P.; Sisco, Edward The Analyst, Vol. 143, Issue 9 https://doi.org/10.1039/C7AN02066J	journal	January 2018
Detection of strep throat causing bacterium directly from medical swabs by touch spray-mass spectrometry Jarmusch, Alan K.; Pirro, Valentina; Kerian, Kevin S. The Analyst, Vol. 139, Issue 19 https://doi.org/10.1039/C4AN00959B	journal	January 2014

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