Mechanical properties of tropomyosin and implications for muscle regulation
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journal
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January 1996 |
Computational simulation of hypertrophic cardiomyopathy mutations in Troponin I: Influence of increased myofilament calcium sensitivity on isometric force, ATPase and [Ca2+]i
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journal
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January 2007 |
Shortening of the Elastic Tandem Immunoglobulin Segment of Titin Leads to Diastolic Dysfunction
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journal
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July 2013 |
The force exerted by a single kinesin molecule against a viscous load
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journal
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August 1994 |
The Sarcomeric Protein Nebulin: Another Multifunctional Giant in Charge of Muscle Strength Optimization
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January 2012 |
A Spatially Explicit Nanomechanical Model of the Half-Sarcomere: Myofilament Compliance Affects Ca 2+ -Activation
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journal
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November 2004 |
Thin filament length in the cardiac sarcomere varies with sarcomere length but is independent of titin and nebulin
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journal
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August 2016 |
X-ray diffraction from striated muscles and nerves in normal and dystrophic mice
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journal
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March 1982 |
Titin/connectin-based modulation of the Frank-Starling mechanism of the heart
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February 2006 |
Dilated cardiomyopathy myosin mutants have reduced force-generating capacity
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April 2018 |
Titin Determines the Frank-Starling Relation in Early Diastole
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January 2003 |
Identification of an N2 line protein of striated muscle.
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journal
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June 1980 |
Visualization of cardiac muscle thin filaments and measurement of their lengths by electron tomography
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journal
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January 2008 |
Titin Isoform Variance and Length Dependence of Activation in Skinned Bovine Cardiac Muscle
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journal
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November 2003 |
Steric-model for activation of muscle thin filaments 1 1 Edited by P.E. Wright
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journal
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February 1997 |
A comparison of muscle thin filament models obtained from electron microscopy reconstructions and low-angle X-ray fibre diagrams from non-overlap muscle
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journal
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August 2006 |
Resolution and uniqueness of estimated parameters of a model of thin filament regulation in solution
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journal
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February 2010 |
Cooperativity and Switching within the Three-State Model of Muscle Regulation †
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journal
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January 1999 |
Nebulin Alters Cross-bridge Cycling Kinetics and Increases Thin Filament Activation: A NOVEL MECHANISM FOR INCREASING TENSION AND REDUCING TENSION COST
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journal
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September 2009 |
Thick Filament Mechano-Sensing in Skeletal and Cardiac Muscles: A Common Mechanism Able to Adapt the Energetic Cost of the Contraction to the Task
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journal
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June 2018 |
Nebulin deficiency in adult muscle causes sarcomere defects and muscle-type-dependent changes in trophicity: novel insights in nemaline myopathy
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journal
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June 2015 |
Three-dimensional stochastic model of actin–myosin binding in the sarcomere lattice
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journal
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November 2016 |
The Giant Muscle Protein Titin is an Adjustable Molecular Spring
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journal
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January 2006 |
Mechanically Driven Contour-Length Adjustment in Rat Cardiac Titin’s Unique N2B Sequence: Titin Is an Adjustable Spring
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journal
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June 1999 |
The Shape and Flexibility of Tropomyosin Coiled Coils: Implications for Actin Filament Assembly and Regulation
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journal
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January 2010 |
Roles of Titin in the Structure and Elasticity of the Sarcomere
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journal
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January 2010 |
Nebulin, a major player in muscle health and disease
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journal
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March 2011 |
Sizes of components in frog skeletal muscle measured by methods of stereology
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journal
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July 1975 |
The myofilament elasticity and its effect on kinetics of force generation by the myosin motor
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journal
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June 2014 |
Cooperative Regulation of Myosin-Actin Interactions by a Continuous Flexible Chain II: Actin-Tropomyosin-Troponin and Regulation by Calcium
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journal
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May 2003 |
Myofilament length dependent activation
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journal
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May 2010 |
Titin-based tension in the cardiac sarcomere: Molecular origin and physiological adaptations
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journal
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October 2012 |
The role of super-relaxed myosin in skeletal and cardiac muscle
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journal
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December 2014 |
The amino acid sequence of bovine cardiac troponin-C. Comparison with rabbit skeletal troponin-C
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journal
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May 1975 |
Titin mutations in iPS cells define sarcomere insufficiency as a cause of dilated cardiomyopathy
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journal
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August 2015 |
Nebulin increases thin filament stiffness and force per cross-bridge in slow-twitch soleus muscle fibers
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journal
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October 2018 |
Nebulin stiffens the thin filament and augments cross-bridge interaction in skeletal muscle
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journal
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September 2018 |
Genetic Variation in Titin in Arrhythmogenic Right Ventricular Cardiomyopathy–Overlap Syndromes
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journal
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August 2011 |
Tropomyosin Length and Two-stranded F-actin Flexibility in the Thin Filament
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journal
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October 1994 |
Persistence Length of Human Cardiac α-Tropomyosin Measured by Single Molecule Direct Probe Microscopy
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journal
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June 2012 |
Myosin filament activation in the heart is tuned to the mechanical task
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journal
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March 2017 |
Nebulin regulates thin filament length, contractility, and Z-disk structure in vivo
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journal
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August 2006 |
Evidence for cross-bridge attachment in relaxed muscle at low ionic strength.
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journal
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December 1982 |
Compliant Realignment of Binding Sites in Muscle: Transient Behavior and Mechanical Tuning
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journal
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April 1998 |
Cooperative [Ca2+]-Dependent Regulation of the Rate of Myosin Binding to Actin: Solution Data and the Tropomyosin Chain Model
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journal
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June 2011 |
Filament Compliance Influences Cooperative Activation of Thin Filaments and the Dynamics of Force Production in Skeletal Muscle
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journal
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May 2012 |
Nebulette: A 107 kD nebulin-like protein in cardiac muscle
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journal
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January 1995 |
Titin and the sarcomere symmetry paradox11Edited by J. Karn
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journal
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January 2001 |
Proposed Mechanism of Force Generation in Striated Muscle
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October 1971 |
Titin Extensibility In Situ: Entropic Elasticity of Permanently Folded and Permanently Unfolded Molecular Segments
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journal
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February 1998 |
Experimentally Increasing Titin Compliance in a Novel Mouse Model Attenuates the Frank-Starling Mechanism But Has a Beneficial Effect on Diastole
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journal
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May 2014 |
Experimentally Increasing the Compliance of Titin Through RNA Binding Motif-20 (RBM20) Inhibition Improves Diastolic Function In a Mouse Model of Heart Failure With Preserved Ejection Fraction
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journal
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October 2016 |
Myosin binding-induced cooperative activation of the thin filament in cardiac myocytes and skeletal muscle fibers
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journal
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April 1995 |
Understanding the Organisation and Role of Myosin Binding Protein C in Normal Striated Muscle by Comparison with MyBP-C Knockout Cardiac Muscle
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journal
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December 2008 |
X-ray diffraction from nonuniformly stretched helical molecules
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journal
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April 2016 |
Structure of co-crystals of tropomyosin and troponin
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journal
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February 1987 |
Nebulin plays a direct role in promoting strong actin-myosin interactions
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journal
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December 2009 |
Mechanical properties of tropomyosin and implications for muscle regulation
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journal
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January 1996 |
A Spatially Explicit Model Shows How Titin Stiffness Modulates Muscle Mechanics and Energetics
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journal
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June 2018 |
Truncation of Titin’s Elastic PEVK Region Leads to Cardiomyopathy With Diastolic Dysfunction
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journal
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September 2009 |
The length–tension curve in muscle depends on lattice spacing
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journal
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September 2013 |
Refinement of the F-Actin Model against X-ray Fiber Diffraction Data by the Use of a Directed Mutation Algorithm
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journal
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December 1993 |
Path-integral theory of an axially confined worm-like chain
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journal
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May 2001 |
Variation of thin filament length in heart muscle
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journal
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May 1977 |
Cooperative regulation of myosin-S1 binding to actin filaments by a continuous flexible Tm–Tn chain
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journal
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October 2012 |
Recessive truncating titin gene, TTN, mutations presenting as centronuclear myopathy
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journal
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August 2013 |
Fast Skeletal Muscle Troponin Activation Increases Force of Mouse Fast Skeletal Muscle and Ameliorates Weakness Due to Nebulin-Deficiency
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journal
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February 2013 |
A Simple Model with Myofilament Compliance Predicts Activation-Dependent Crossbridge Kinetics in Skinned Skeletal Fibers
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journal
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December 2002 |
Elasticity of -Helical Coiled Coils
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journal
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December 2006 |
Mouse intact cardiac myocyte mechanics: cross-bridge and titin-based stress in unactivated cells
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journal
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December 2010 |
Length-dependent activation: its effect on the length-tension relation in cat ventricular muscle.
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journal
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March 1977 |
Electron Microscopy and Persistence Length Analysis of Semi-Rigid Smooth Muscle Tropomyosin Strands
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journal
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August 2010 |
Extensibility and Symmetry of Actin Filaments in Contracting Muscles
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journal
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December 1999 |
The Filament Lattice of Striated Muscle
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journal
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April 1998 |
Calcium binding to cardiac troponin C
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journal
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March 1978 |
Genotype?phenotype correlations in nemaline myopathy caused by mutations in the genes for nebulin and skeletal muscle ?-actin
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journal
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September 2004 |
Modeling the Actin.myosin ATPase Cross-Bridge Cycle for Skeletal and Cardiac Muscle Myosin Isoforms
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journal
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March 2017 |
Altered myofilament function depresses force generation in patients with nebulin-based nemaline myopathy (NEM2)
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journal
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May 2010 |
Cooperative Regulation of Myosin-Actin Interactions by a Continuous Flexible Chain I: Actin-Tropomyosin Systems
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journal
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May 2003 |
Sarcomere-length dependence of lattice volume and radial mass transfer of myosin cross-bridges in rat papillary muscle
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journal
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May 2004 |
Distinct contributions of the thin and thick filaments to length-dependent activation in heart muscle
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journal
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February 2017 |
Single Molecule Force Spectroscopy on Titin Implicates Immunoglobulin Domain Stability as a Cardiac Disease Mechanism
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journal
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January 2013 |
Mutations of TTN, encoding the giant muscle filament titin, cause familial dilated cardiomyopathy
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journal
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January 2002 |
Cardiac Titin and Heart Disease
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journal
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January 2014 |
Thin filament length dysregulation contributes to muscle weakness in nemaline myopathy patients with nebulin deficiency
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journal
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April 2009 |
Myofilament lattice spacing as a function of sarcomere length in isolated rat myocardium
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journal
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November 2000 |
The relationship between curvature, flexibility and persistence length in the tropomyosin coiled-coil
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journal
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May 2010 |
Myosin Head Configurations in Resting and Contracting Murine Skeletal Muscle
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journal
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September 2018 |
Congenital Titinopathy: Comprehensive characterization and pathogenic insights
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journal
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May 2018 |
Passive tension in cardiac muscle: contribution of collagen, titin, microtubules, and intermediate filaments
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journal
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March 1995 |
Nebulin as a length regulator of thin filaments of vertebrate skeletal muscles: correlation of thin filament length, nebulin size, and epitope profile
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journal
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October 1991 |
SH3 in muscles: solution structure of the SH3 domain from nebulin
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journal
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February 1998 |
Role of titin in cardiomyopathy: from DNA variants to patient stratification
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journal
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December 2017 |
Interactions Between Connected Half-Sarcomeres Produce Emergent Mechanical Behavior in a Mathematical Model of Muscle
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journal
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January 2010 |
Evidence that nebulin is a protein-ruler in muscle thin filaments
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journal
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May 1991 |
X-ray diffraction measurements of the extensibility of actin and myosin filaments in contracting muscle
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journal
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December 1994 |
Architecture and function in the muscle sarcomere
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journal
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April 1997 |
Novel mutations in NEB cause abnormal nebulin expression and markedly impaired muscle force generation in severe nemaline myopathy
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journal
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January 2011 |
Comparison between the sarcomere length-force relations of intact and skinned trabeculae from rat right ventricle. Influence of calcium concentrations on these relations.
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journal
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June 1986 |
Titin strain contributes to the Frank–Starling law of the heart by structural rearrangements of both thin- and thick-filament proteins
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journal
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February 2016 |
Titin: major myofibrillar components of striated muscle.
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journal
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August 1979 |
Regulation of the interaction between actin and myosin subfragment 1: evidence for three states of the thin filament
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journal
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August 1993 |
The Stiffness of Skeletal Muscle in Isometric Contraction and Rigor: The Fraction of Myosin Heads Bound to Actin
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journal
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May 1998 |
The Complete Mouse Nebulin Gene Sequence and the Identification of Cardiac Nebulin
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journal
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May 2003 |
Direct measurement of stiffness of single actin filaments with and without tropomyosin by in vitro nanomanipulation.
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journal
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December 1994 |
Titin-based modulation of active tension and interfilament lattice spacing in skinned rat cardiac muscle
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journal
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November 2004 |
Sarcoplasmic reticulum calcium uptake and speed of relaxation are depressed in nebulin-free skeletal muscle
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journal
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August 2008 |
Exploration of pathomechanisms triggered by a single-nucleotide polymorphism in titin's I-band: the cardiomyopathy-linked mutation T2580I
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journal
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September 2016 |
The Hill Model for Binding Myosin S1 to Regulated Actin Is not Equivalent to the McKillop–Geeves Model
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journal
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March 2012 |
Molecular model of muscle contraction
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journal
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March 1999 |
Effects of cross-bridge compliance on the force-velocity relationship and muscle power output
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journal
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December 2017 |
Interactions between Connected Half-Sarcomeres Produce Emergent Mechanical Behavior in a Mathematical Model of Muscle
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journal
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November 2009 |
The measurement and dynamic implications of thin filament lengths in heart muscle.
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journal
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January 1979 |
Regulation of Contraction by the Thick Filaments in Skeletal Muscle
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journal
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December 2017 |
Titin-Based Modulation of Calcium Sensitivity of Active Tension in Mouse Skinned Cardiac Myocytes
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journal
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May 2001 |
Compliance of thin filaments in skinned fibers of rabbit skeletal muscle
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journal
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September 1995 |
Titin Is a Major Human Disease Gene
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journal
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February 2013 |
Mutations in the nebulin gene associated with autosomal recessive nemaline myopathy
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journal
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March 1999 |
Connectin, an Elastic Protein of Muscle. Identification of “Titin” with Connectin1
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journal
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January 1981 |
Regulation of Contraction in Striated Muscle
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journal
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January 2000 |
X-ray diffraction evidence for the extensibility of actin and myosin filaments during muscle contraction
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journal
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December 1994 |
Single Particle Analysis of Relaxed and Activated Muscle Thin Filaments
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journal
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February 2005 |
Molecular Mechanics of Cardiac Titin's PEVK and N2B Spring Elements
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journal
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March 2002 |
Length, force, and Ca(2+)-troponin C affinity in cardiac and slow skeletal muscle
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journal
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April 1994 |
Force generation by skeletal muscle is controlled by mechanosensing in myosin filaments
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journal
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November 2015 |
Differential Expression of Cardiac Titin Isoforms and Modulation of Cellular Stiffness
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journal
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January 2000 |
Truncations of Titin Causing Dilated Cardiomyopathy
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journal
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February 2012 |
The calcium and magnesium binding sites on cardiac troponin and their role in the regulation of myofibrillar adenosine triphosphatase.
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journal
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December 1980 |
Proteolytic fragments of troponin C. Localization of high and low affinity Ca2+ binding sites and interactions with troponin I and troponin T
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journal
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August 1978 |
The calcium and magnesium binding sites on troponin and their role in the regulation of myofibrillar adenosine triphosphatase.
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journal
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June 1975 |