Cellobiohydrolase variants and polynucleotides encoding same

Wogulis, Mark

Title: Cellobiohydrolase variants and polynucleotides encoding same

Patent · Tue Dec 04 00:00:00 EST 2018

OSTI ID:1496628

Wogulis, Mark

The present invention relates to variants of a parent cellobiohydrolase II. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.

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Research Organization:: Novozymes, Inc., David, CA (United States)

Sponsoring Organization:: USDOE

DOE Contract Number:: FC36-08GO18080

Assignee:: Novozymes, Inc. (David, CA)

Patent Number(s):: 10,144,920

Application Number:: 15/446,676

OSTI ID:: 1496628

Resource Relation:: Patent File Date: 2017 Mar 01

Country of Publication:: United States

Language:: English

References (6)

Polypeptides having cellobiohydrolase activity and polynucleotides encoding same Brown, Kimberly; Harris, Paul; Lopez de Leon, Alfredo https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/7220565 US Patent Document 7,220,565	patent	May 2007
Polypeptides having cellobiohydrolase activity and polynucleotides encoding same Liu, Ye; Tang, Lan; Harris, Paul https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/8278507 US Patent Document 8,278,507	patent	October 2012
A family of thermostable fungal cellulases created by structure-guided recombination Heinzelman, P.; Snow, C. D.; Wu, I. Proceedings of the National Academy of Sciences, Vol. 106, Issue 14, p. 5610-5615 https://doi.org/10.1073/pnas.0901417106	journal	March 2009
SCHEMA Recombination of a Fungal Cellulase Uncovers a Single Mutation That Contributes Markedly to Stability Heinzelman, Pete; Snow, Christopher D.; Smith, Matthew A. Journal of Biological Chemistry, Vol. 284, Issue 39, p. 26229-26233 https://doi.org/10.1074/jbc.C109.034058	journal	July 2009
Protein tolerance to random amino acid change Guo, H. H.; Choe, J.; Loeb, L. A. Proceedings of the National Academy of Sciences, Vol. 101, Issue 25, p. 9205-9210 https://doi.org/10.1073/pnas.0403255101	journal	June 2004
Biomass Recalcitrance: Engineering Plants and Enzymes for Biofuels Production Himmel, M. E.; Ding, S.-Y.; Johnson, D. K. Science, Vol. 315, Issue 5813, p. 804-807 https://doi.org/10.1126/science.1137016	journal	February 2007

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