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|
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|
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Energetic Characterization of the Basic Fibroblast Growth Factor-Heparin Interaction: Identification of the Heparin Binding Domain
|
journal
|
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Vascular and Neurogenic Rejuvenation of the Aging Mouse Brain by Young Systemic Factors
|
journal
|
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Transforming growth factor-β superfamily ligand trap ACE-536 corrects anemia by promoting late-stage erythropoiesis
|
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|
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Gdf-8 Propeptide Binds to GDF-8 and Antagonizes Biological Activity by Inhibiting GDF-8 Receptor Binding
|
journal
|
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Ternary Complex of Transforming Growth Factor-β1 Reveals Isoform-specific Ligand Recognition and Receptor Recruitment in the Superfamily
|
journal
|
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Molecular recognition of BMP-2 and BMP receptor IA
|
journal
|
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Structural insights into BMP receptors: Specificity, activation and inhibition
|
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|
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A Novel Role of Follistatin, an Activin-binding Protein, in the Inhibition of Activin Action in Rat Pituitary Cells: ENDOCYTOTIC DEGRADATION OF ACTIVIN AND ITS ACCELERATION BY FOLLISTATIN ASSOCIATED WITH CELL-SURFACE HEPARAN SULFATE
|
journal
|
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Restoring Systemic GDF11 Levels Reverses Age-Related Dysfunction in Mouse Skeletal Muscle
|
journal
|
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Identification of Novel Inhibitors of the Transforming Growth Factor β1 (TGF-β1) Type 1 Receptor (ALK5)
|
journal
|
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Type I receptor binding of bone morphogenetic protein 6 is dependent on N-glycosylation of the ligand: Type I receptor specificity of BMP-6
|
journal
|
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Growth Differentiation Factor 11 Is a Circulating Factor that Reverses Age-Related Cardiac Hypertrophy
|
journal
|
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A Flexible Activin Explains the Membrane-Dependent Cooperative Assembly of TGF-β Family Receptors
|
journal
|
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Follistatin Gene Delivery Enhances Muscle Growth and Strength in Nonhuman Primates
|
journal
|
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Structural basis for the inhibition of activin signalling by follistatin
|
journal
|
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Differential regulation of follicle stimulating hormone by activin A and TGFB1 in murine gonadotropes
|
journal
|
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The structure of myostatin:follistatin 288: insights into receptor utilization and heparin binding
|
journal
|
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Identification of human activin and TGFβ type I receptors that form heteromeric kinase complexes with type II receptors
|
journal
|
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Structural basis for specificity of TGFβ family receptor small molecule inhibitors
|
journal
|
February 2012 |
A Novel BMP Expressed in Developing Mouse Limb, Spinal Cord, and Tail Bud Is a Potent Mesoderm Inducer inXenopusEmbryos
|
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|
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Beyond CDR-grafting: Structure-guided humanization of framework and CDR regions of an anti-myostatin antibody
|
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|
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Regulation of anterior/posterior patterning of the axial skeleton by growth/differentiation factor 11
|
journal
|
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Myostatin reduces Akt/TORC1/p70S6K signaling, inhibiting myoblast differentiation and myotube size
|
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|
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TGFβ Signaling and Cardiovascular Diseases
|
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|
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GDF11 Controls the Timing of Progenitor Cell Competence in Developing Retina
|
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|
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The Myostatin Propeptide and the Follistatin-related Gene Are Inhibitory Binding Proteins of Myostatin in Normal Serum
|
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|
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A Single Residue of GDF-5 Defines Binding Specificity to BMP Receptor IB
|
journal
|
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Bone morphogenetic protein 2 and activin A synergistically stimulate follicle-stimulating hormone β subunit transcription
|
journal
|
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Activin B can signal through both ALK4 and ALK7 in gonadotrope cells
|
journal
|
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Myostatin Signals through a Transforming Growth Factor -Like Signaling Pathway To Block Adipogenesis
|
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|
September 2003 |
Biological Activity of Follistatin Isoforms and Follistatin-Like-3 Is Dependent on Differential Cell Surface Binding and Specificity for Activin, Myostatin, and Bone Morphogenetic Proteins
|
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|
July 2006 |
Gene Therapy for Duchenne Muscular Dystrophy: Expectations and Challenges
|
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|
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Inhibition of myostatin with emphasis on follistatin as a therapy for muscle disease
|
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|
March 2009 |
Lack of evidence for GDF11 as a rejuvenator of aged skeletal muscle satellite cells
|
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|
March 2016 |
Inhibin A and B in Vitro Bioactivities Are Modified by Their Degree of Glycosylation and Their Affinities to Betaglycan
|
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|
May 2007 |
Regulation of skeletal muscle mass in mice by a new TGF-p superfamily member
|
journal
|
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Crystal structure of human GDF11
|
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|
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Reduced Circulating GDF11 Is Unlikely Responsible for Age-Dependent Changes in Mouse Heart, Muscle, and Brain
|
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|
November 2015 |
Repulsive guidance molecule is a structural bridge between neogenin and bone morphogenetic protein
|
journal
|
May 2015 |
Gdf11 Is a Negative Regulator of Chondrogenesis and Myogenesis in the Developing Chick Limb
|
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|
January 2001 |
Growth and differentiation factor-11 is developmentally regulated in skeletal muscle and inhibits myoblast differentiation
|
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|
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Development of a Small-Molecule Screening Method for Inhibitors of Cellular Response to Myostatin and Activin A
|
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|
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The bright and the dark sides of activin in wound healing and cancer
|
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|
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Biological Activity Differences between TGF-β1 and TGF-β3 Correlate with Differences in the Rigidity and Arrangement of Their Component Monomers
|
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|
September 2014 |
Induction of Cachexia in Mice by Systemically Administered Myostatin
|
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|
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BMP signalling: agony and antagony in the family
|
journal
|
May 2015 |
Regulation of myostatin activity and muscle growth
|
journal
|
July 2001 |
Activin isoforms signal through type I receptor serine/threonine kinase ALK7
|
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|
May 2004 |
GDF11 Increases with Age and Inhibits Skeletal Muscle Regeneration
|
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|
July 2015 |
Conformation and Self-association of Human Recombinant Transforming Growth Factor-β3 in Aqueous Solutions
|
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|
March 1999 |
Mammalian BMP-1/Tolloid-Related Metalloproteinases, Including Novel Family Member Mammalian Tolloid-Like 2, Have Differential Enzymatic Activities and Distributions of Expression Relevant to Patterning and Skeletogenesis
|
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|
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Structure of Myostatin·Follistatin-like 3: N-TERMINAL DOMAINS OF FOLLISTATIN-TYPE MOLECULES EXHIBIT ALTERNATE MODES OF BINDING
|
journal
|
November 2011 |
Structure of the ternary signaling complex of a TGF-beta superfamily member
|
journal
|
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GDF11 Does Not Rescue Aging-Related Pathological Hypertrophy
|
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|
November 2015 |
Latent TGF-β structure and activation
|
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|
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GDF11 modulates NGN3+ islet progenitor cell number and promotes -cell differentiation in pancreas development
|
journal
|
November 2004 |
Heparin and Activin-Binding Determinants in Follistatin and FSTL3
|
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|
January 2005 |
Regulation of GDF-11 and myostatin activity by GASP-1 and GASP-2
|
journal
|
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The Structure of the Follistatin:Activin Complex Reveals Antagonism of Both Type I and Type II Receptor Binding
|
journal
|
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The Structure of FSTL3·Activin A Complex
|
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|
September 2008 |
Differential Binding Activity of TGF- Family Proteins to Select TGF- Receptors
|
journal
|
June 2016 |
Direct binding of Smad3 and Smad4 to critical TGFbeta -inducible elements in the promoter of human plasminogen activator inhibitor-type 1gene
|
journal
|
June 1998 |
Cooperative Assembly of TGF-β Superfamily Signaling Complexes Is Mediated by Two Disparate Mechanisms and Distinct Modes of Receptor Binding
|
journal
|
February 2008 |
Inhibition of Transforming Growth Factor (TGF)-β1–Induced Extracellular Matrix with a Novel Inhibitor of the TGF-β Type I Receptor Kinase Activity: SB-431542
|
journal
|
July 2002 |
Circulating Growth Differentiation Factor 11/8 Levels Decline With Age
|
journal
|
January 2016 |
Crystal structure of human bone morphogenetic protein-2 at 2.7 Å resolution 1 1Edited by R. Huber
|
journal
|
March 1999 |
Extracellular Regulation of Myostatin: A Molecular Rheostat for Muscle Mass
|
journal
|
December 2010 |
Double muscling in cattle due to mutations in the myostatin gene
|
journal
|
November 1997 |
Regulation of Myostatin in Vivo by Growth and Differentiation Factor-Associated Serum Protein-1: A Novel Protein with Protease Inhibitor and Follistatin Domains
|
journal
|
June 2003 |
The function of growth/differentiation factor 11 (Gdf11) in rostrocaudal patterning of the developing spinal cord
|
journal
|
August 2006 |
Structures of an ActRIIB:activin A complex reveal a novel binding mode for TGF-beta ligand:receptor interactions
|
journal
|
April 2003 |
Characterization of Follistatin-Type Domains and Their Contribution to Myostatin and Activin A Antagonism
|
journal
|
July 2012 |
Characterization and identification of the inhibitory domain of GDF-8 propeptide
|
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|
March 2004 |
SB-431542 Is a Potent and Specific Inhibitor of Transforming Growth Factor-β Superfamily Type I Activin Receptor-Like Kinase (ALK) Receptors ALK4, ALK5, and ALK7
|
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|
July 2002 |
Functional improvement of dystrophic muscle by myostatin blockade
|
journal
|
November 2002 |
A human protein containing multiple types of protease-inhibitory modules
|
journal
|
March 2001 |
Activation of latent myostatin by the BMP-1/tolloid family of metalloproteinases
|
journal
|
December 2003 |
Growth differentiation factor 11 signals through the transforming growth factor-β receptor ALK5 to regionalize the anterior–posterior axis
|
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|
July 2006 |
Gene Therapy for Duchenne Muscular Dystrophy
|
book
|
June 2010 |
Type I receptors specify growth-inhibitory and transcriptional responses to transforming growth factor beta and activin
|
journal
|
June 1994 |
TGFβ Signaling and Cardiovascular Diseases
|
journal
|
January 2012 |
Understanding the role of Cripto-1 in cancer progression and therapeutic strategies
|
journal
|
December 2022 |
Cloning of a TGF$beta; type I receptor that forms a heteromeric complex with the TGF$beta; type II receptor
|
journal
|
November 1993 |
Purification and characterization of recombinant human activin B
|
journal
|
June 1990 |
Inhibition of myostatin in adult mice increases skeletal muscle mass and strength
|
journal
|
January 2003 |
Autoregulation of Neurogenesis by GDF11
|
journal
|
January 2003 |
Biological functions of the WAP domain-containing multidomain proteins WFIKKN1 and WFIKKN2
|
journal
|
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Alternative Binding Modes Identified for Growth and Differentiation Factor-associated Serum Protein (GASP) Family Antagonism of Myostatin
|
journal
|
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Dynamics-modulated Biological Activity of Transforming Growth Factor β3
|
journal
|
September 2002 |
Structural and Biophysical Coupling of Heparin and Activin Binding to Follistatin Isoform Functions
|
journal
|
April 2007 |
Identification of a Novel Pool of Extracellular Pro-myostatin in Skeletal Muscle
|
journal
|
January 2008 |
Both WFIKKN1 and WFIKKN2 Have High Affinity for Growth and Differentiation Factors 8 and 11
|
journal
|
July 2008 |
A Transforming Growth Factor β Type I Receptor that Signals to Activate Gene Expression
|
journal
|
January 1994 |
Type I receptors specify growth-inhibitory and transcriptional responses to transforming growth factor beta and activin.
|
journal
|
June 1994 |
GDF11 Forms a Bone Morphogenetic Protein 1-Activated Latent Complex That Can Modulate Nerve Growth Factor-Induced Differentiation of PC12 Cells
|
journal
|
June 2005 |
Is Growth Differentiation Factor 11 a Realistic Therapeutic for Aging-Dependent Muscle Defects?
|
journal
|
April 2016 |
Biochemistry and Biology of GDF11 and Myostatin: Similarities, Differences, and Questions for Future Investigation
|
journal
|
April 2016 |
Redundancy of myostatin and growth/differentiation factor 11 function
|
journal
|
March 2009 |
Distinct Expression Pattern of Two Related Human Proteins Containing Multiple Types of Protease-Inhibitory Modules
|
journal
|
January 2002 |