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Title: Metazen – metadata capture for metagenomes

Journal Article · · Standards in Genomic Sciences
 [1];  [1];  [1];  [1];  [1];  [1]
  1. Univ. of Chicago, Chicago, IL (United States); Argonne National Lab. (ANL), Argonne, IL (United States)

Background: As the impact and prevalence of large-scale metagenomic surveys grow, so does the acute need for more complete and standards compliant metadata. Metadata (data describing data) provides an essential complement to experimental data, helping to answer questions about its source, mode of collection, and reliability. Metadata collection and interpretation have become vital to the genomics and metagenomics communities, but considerable challenges remain, including exchange, curation, and distribution. Currently, tools are available for capturing basic field metadata during sampling, and for storing, updating and viewing it. These tools are not specifically designed for metagenomic surveys; in particular, they lack the appropriate metadata collection templates, a centralized storage repository, and a unique ID linking system that can be used to easily port complete and compatible metagenomic metadata into widely used assembly and sequence analysis tools. Results: Metazen was developed as a comprehensive framework designed to enable metadata capture for metagenomic sequencing projects. Specifically, Metazen provides a rapid, easy-to-use portal to encourage early deposition of project and sample metadata. Conclusion: Metazen is an interactive tool that aids users in recording their metadata in a complete and valid format. A defined set of mandatory fields captures vital information, while the option to add fields provides flexibility.

Research Organization:
Argonne National Laboratory (ANL), Argonne, IL (United States)
Sponsoring Organization:
USDOE Office of Science (SC)
Grant/Contract Number:
AC02-06CH11357
OSTI ID:
1224089
Journal Information:
Standards in Genomic Sciences, Vol. 9, Issue 1; ISSN 1944-3277
Publisher:
BioMed CentralCopyright Statement
Country of Publication:
United States
Language:
English
Citation Metrics:
Cited by: 4 works
Citation information provided by
Web of Science

References (12)

The minimum information about a genome sequence (MIGS) specification journal May 2008
VAMPS: a website for visualization and analysis of microbial population structures journal February 2014
A Standard MIGS/MIMS Compliant XML Schema: Toward the Development of the Genomic Contextual Data Markup Language (GCDML) journal June 2008
The metagenomics RAST server – a public resource for the automatic phylogenetic and functional analysis of metagenomes journal September 2008
IMG/M: the integrated metagenome data management and comparative analysis system journal November 2011
Sugars dominate the seagrass rhizosphere text January 2022
Minimum information about a marker gene sequence (MIMARKS) and minimum information about any (x) sequence (MIxS) specifications journal May 2011
Infant gut microbiota characteristics generally do not modify effects of lipid-based nutrient supplementation on growth or inflammation: secondary analysis of a randomized controlled trial in Malawi journal September 2020
QIIME allows analysis of high-throughput community sequencing data journal April 2010
The Genomes OnLine Database (GOLD) v.4: status of genomic and metagenomic projects and their associated metadata journal December 2011
Community cyberinfrastructure for Advanced Microbial Ecology Research and Analysis: the CAMERA resource journal November 2010
ISA software suite: supporting standards-compliant experimental annotation and enabling curation at the community level journal August 2010

Cited By (4)

Genomes OnLine Database (GOLD) v.6: data updates and feature enhancements journal October 2016
MG-RAST version 4—lessons learned from a decade of low-budget ultra-high-throughput metagenome analysis journal September 2017
Value, but high costs in post-deposition data curation journal January 2016
The MG-RAST metagenomics database and portal in 2015 journal December 2015