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Title: Samarium-145 and its use as a radiation source

Patent ·
OSTI ID:1176605

The present invention covers a new radiation source, samarium-145, with radiation energies slightly above those of I-125 and a half-life of 340 days. The samarium-145 source is produced by neutron irradiation of SM-144. This new source is useful as the implanted radiation source in photon activation therapy of malignant tumors to activate the stable I-127 contained in the IdUrd accumulated in the tumor, causing radiation sensitization and Auger cascades that irreperably damage the tumor cells. This new source is also useful as a brachytherapy source.

Research Organization:
Brookhaven National Laboratory (BNL), Upton, NY (United States)
Sponsoring Organization:
USDOE
DOE Contract Number:
AC02-76CH00016
Assignee:
United States Of America, Department Of Energy
Patent Number(s):
H000669
Application Number:
06/938839
OSTI ID:
1176605
Resource Relation:
Patent File Date: 1986 Dec 08
Country of Publication:
United States
Language:
English

References (1)

Radiation Enhancement with Iodinated Deoxyuridine journal July 1982