High Sensitivity SPECT for Small Animals and Plants

Technical Report · Wed Sep 01 00:00:00 EDT 2010

DOI:https://doi.org/10.2172/1171466· OSTI ID:1171466

Mitchell, Gregory S. ^[1]

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1. University of California, Davis, CA (United States)

Imaging systems using single gamma-ray emitting radioisotopes typically implement collimators in order to form the images. However, a tradeoff in sensitivity is inherent in the use of collimators, and modern preclinical single-photon emission computed tomography (SPECT) systems detect a very small fraction of emitted gamma-rays (<0.3%). We have built a collimator-less system, which can reach sensitivity of 40% for ⁹⁹mTc imaging, while still producing images of sufficient spatial resolution for certain applications in thin objects such as mice, small plants, and well plates used for in vitro experiments.

• Research Organization: Univ. of California, Davis, CA (United States)
• Sponsoring Organization: USDOE Office of Science (SC), Biological and Environmental Research (BER)
• DOE Contract Number: SC0005311
• OSTI ID: 1171466
• Report Number(s): DOE-UCDAVIS-05311
• Country of Publication: United States
• Language: English

Related Subjects

SPECT
nuclear imaging
plant imaging