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Title: DNA-based methods of geochemical prospecting

Patent ·
OSTI ID:1034343
 [1]
  1. Mill Valley, CA
+ Show Author Affiliations

The present invention relates to methods for performing surveys of the genetic diversity of a population. The invention also relates to methods for performing genetic analyses of a population. The invention further relates to methods for the creation of databases comprising the survey information and the databases created by these methods. The invention also relates to methods for analyzing the information to correlate the presence of nucleic acid markers with desired parameters in a sample. These methods have application in the fields of geochemical exploration, agriculture, bioremediation, environmental analysis, clinical microbiology, forensic science and medicine.

Research Organization:
Ashby Matt
Sponsoring Organization:
USDOE
DOE Contract Number:
FG36-01GO11016
Assignee:
Ashby Matt
Patent Number(s):
8,071,295
Application Number:
10/607,077
OSTI ID:
1034343
Country of Publication:
United States
Language:
English

References (21)

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Identification and Phylogenetic Analysis of Thermophilic Sulfate-Reducing Bacteria in Oil Field Samples by 16S rDNA Gene Cloning and Sequencing journal June 1998
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Distribution of Bifidobacterial Species in Human Intestinal Microflora Examined with 16S rRNA-Gene-Targeted Species-Specific Primers journal October 1999
Characterization of microbial diversity by determining terminal restriction fragment length polymorphisms of genes encoding 16S rRNA. journal January 1997
DNA recovery and PCR quantification of catechol 2,3-dioxygenase genes from different soil types journal December 1996
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Phylogeny of the Main Bacterial 16S rRNA Sequences in Drentse A Grassland Soils (The Netherlands) journal March 1998
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A phylogenetic tree of 16S rRNA sequences from sulfate-reducing bacteria in a sandy marine sediment. journal January 1994
A Molecular View of Microbial Diversity and the Biosphere journal May 1997
Non-cloning amplification of specific DNA fragments from whole genomic DNA digests using DNA ‘indexers’ journal August 1994
Serial Analysis of Gene Expression journal October 1995
Determination of microbial diversity in environmental samples: pitfalls of PCR-based rRNA analysis journal November 1997
Impact of Culture-Independent Studies on the Emerging Phylogenetic View of Bacterial Diversity journal September 1998
Detection and Identification of Previously Unrecognized Microbial Pathogens journal September 1998
Gene Expression Profiles in Normal and Cancer Cells journal May 1997
Frequency of formation of chimeric molecules as a consequence of PCR coamplification of 16S rRNA genes from mixed bacterial genomes. journal January 1997
Characterization of the diversity of sulfate-reducing bacteria in soil and mining waste water environments by nucleic acid hybridization techniques journal November 1994
Effect of genome size and rrn gene copy number on PCR amplification of 16S rRNA genes from a mixture of bacterial species. journal January 1995

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Related Subjects

59 BASIC BIOLOGICAL SCIENCES