Health effects models for nuclear power plant accident consequence analysis. Part 1, Introduction, integration, and summary: Revision 2
- Harvard School of Public Health, Boston, MA (United States)
- Wisconsin Univ., Madison, WI (United States)
- Brookhaven National Lab., Upton, NY (United States)
- Inhalation Toxicology Research Inst., Albuquerque, NM (United States)
- Battelle Pacific Northwest Lab., Richland, WA (United States)
This report is a revision of NUREG/CR-4214, Rev. 1, Part 1 (1990), Health Effects Models for Nuclear Power Plant Accident Consequence Analysis. This revision has been made to incorporate changes to the Health Effects Models recommended in two addenda to the NUREG/CR-4214, Rev. 1, Part 11, 1989 report. The first of these addenda provided recommended changes to the health effects models for low-LET radiations based on recent reports from UNSCEAR, ICRP and NAS/NRC (BEIR V). The second addendum presented changes needed to incorporate alpha-emitting radionuclides into the accident exposure source term. As in the earlier version of this report, models are provided for early and continuing effects, cancers and thyroid nodules, and genetic effects. Weibull dose-response functions are recommended for evaluating the risks of early and continuing health effects. Three potentially lethal early effects -- the hematopoietic, pulmonary, and gastrointestinal syndromes are considered. Linear and linear-quadratic models are recommended for estimating the risks of seven types of cancer in adults - leukemia, bone, lung, breast, gastrointestinal, thyroid, and ``other``. For most cancers, both incidence and mortality are addressed. Five classes of genetic diseases -- dominant, x-linked, aneuploidy, unbalanced translocations, and multifactorial diseases are also considered. Data are provided that should enable analysts to consider the timing and severity of each type of health risk.
- Research Organization:
- US Nuclear Regulatory Commission (NRC), Washington, DC (United States). Div. of Regulatory Applications; Inhalation Toxicology Research Inst., Albuquerque, NM (United States)
- Sponsoring Organization:
- Nuclear Regulatory Commission, Washington, DC (United States)
- OSTI ID:
- 10189279
- Report Number(s):
- NUREG/CR-4214-Rev.2-Pt.1; ITRI-141; ON: TI94001451; TRN: 93:025528
- Resource Relation:
- Other Information: PBD: Oct 1993
- Country of Publication:
- United States
- Language:
- English
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63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
NUCLEAR POWER PLANTS
REACTOR ACCIDENTS
HEALTH HAZARDS
REACTOR SAFETY
BIOLOGICAL RADIATION EFFECTS
RADIOISOTOPES
MORTALITY
NEOPLASMS
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RADIONUCLIDE EFFECTS, KINETICS, AND TOXICOLOGY