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Title: Passive chip-based droplet sorting

Patent ·
OSTI ID:1224965

An apparatus for passive sorting of microdroplets including a main flow channel, a flow stream of microdroplets in the main flow channel wherein the microdroplets have substantially the same diameter and wherein the flow stream of microdroplets includes first microdroplets having a first degree of stiffness and second microdroplets having a second degree of stiffness wherein the second degree of stiffness is different than the first degree of stiffness. A second flow channel is connected to the main flow channel for the second microdroplets having a second degree of stiffness. A separator separates the second microdroplets having a second degree of stiffness from the first microdroplets and directs the second microdroplets having a second degree of stiffness into the second flow channel.

Research Organization:
Lawrence Livermore National Laboratory (LLNL), Livermore, CA (United States)
Sponsoring Organization:
USDOE
DOE Contract Number:
AC52-07NA27344
Assignee:
Lawrence Livermore National Security, LLC
Patent Number(s):
9,174,213
Application Number:
14/629,930
OSTI ID:
1224965
Resource Relation:
Patent File Date: 2015 Feb 24
Country of Publication:
United States
Language:
English

References (12)

Microfluidic magnetophoretic device and methods for using the same patent October 2010
Particle quantifying systems and methods using acoustic radiation pressure patent November 2012
Methods and apparatus for sorting cells using an optical switch in a microfluidic channel network patent April 2013
Manipulation of microfluidic droplets patent September 2013
Microfabricated crossflow devices and methods patent-application May 2002
Methods and apparatus for sorting cells using an optical switch in a microfluidic channel network patent-application September 2005
The Cross-linking of Proteins with Glutaraldehyde and its use for the preparation of immunoadsorbents journal January 1969
Isothermal surface production and regulation for high heat flux applications utilizing porous inserts journal August 2001
Inducing and Sensing Protein–Protein Interactions in Living Cells by Selective Cross-linking journal June 2007
Self-Assembly and Cross-Linking of Bionanoparticles at Liquid-Liquid Interfaces journal April 2005
Metal-Mediated Self-Assembly of Protein Superstructures: Influence of Secondary Interactions on Protein Oligomerization and Aggregation journal May 2008
Photo-leucine and photo-methionine allow identification of protein-protein interactions in living cells journal March 2005

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